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Page 1
Harnessing the spatial and transcriptional regulation of monoterpenoid indole alkaloid metabolism in Alstonia scholaris leads to the identification of broad geissoschizine cyclase activities.
Méteignier LV, Szwarc S, Barunava P, Durand M, Zamar DL, Birer Williams C, Gautron N, Dutilleul C, Koudounas K, Lezin E, Perrot T, Oudin A, Pateyron S, Delannoy E, Brunaud V, Lanoue A, Abbasi BH, St-Pierre B, Jensen MK, Papon N, Sun C, Le Pogam P, Yuan L, Beniddir MA, Besseau S, Courdavault V. Méteignier LV, et al. Among authors: koudounas k. Plant Physiol Biochem. 2024 Nov 29;219:109363. doi: 10.1016/j.plaphy.2024.109363. Online ahead of print. Plant Physiol Biochem. 2024. PMID: 39657422 Free article.
Genome-based discovery of pachysiphine synthases in Tabernaemontana elegans.
Lezin E, Durand M, Birer Williams C, Lopez Vazquez AL, Perrot T, Gautron N, Pétrignet J, Cuello C, Jansen HJ, Magot F, Szwarc S, Le Pogam P, Beniddir MA, Koudounas K, Oudin A, St-Pierre B, Giglioli-Guivarc'h N, Sun C, Papon N, Jensen MK, Dirks RP, O'Connor SE, Besseau S, Courdavault V. Lezin E, et al. Among authors: koudounas k. Plant J. 2024 Dec;120(5):1880-1900. doi: 10.1111/tpj.17085. Epub 2024 Oct 20. Plant J. 2024. PMID: 39427334 Free PMC article.
Yeast Platforms for Production and Screening of Bioactive Derivatives of Rauwolscine.
Bradley SA, Hansson FG, Lehka BJ, Rago D, Pinho P, Peng H, Adhikari KB, Haidar AK, Hansen LG, Volkova D, Holtz M, Muyo Abad S, Ma X, Koudounas K, Besseau S, Gautron N, Mélin C, Marc J, Birer Williams C, Courdavault V, Jensen ED, Keasling JD, Zhang J, Jensen MK. Bradley SA, et al. Among authors: koudounas k. ACS Synth Biol. 2024 May 17;13(5):1498-1512. doi: 10.1021/acssynbio.4c00039. Epub 2024 Apr 18. ACS Synth Biol. 2024. PMID: 38635307
Biosynthesis of natural and halogenated plant monoterpene indole alkaloids in yeast.
Bradley SA, Lehka BJ, Hansson FG, Adhikari KB, Rago D, Rubaszka P, Haidar AK, Chen L, Hansen LG, Gudich O, Giannakou K, Lengger B, Gill RT, Nakamura Y, de Bernonville TD, Koudounas K, Romero-Suarez D, Ding L, Qiao Y, Frimurer TM, Petersen AA, Besseau S, Kumar S, Gautron N, Melin C, Marc J, Jeanneau R, O'Connor SE, Courdavault V, Keasling JD, Zhang J, Jensen MK. Bradley SA, et al. Among authors: koudounas k. Nat Chem Biol. 2023 Dec;19(12):1551-1560. doi: 10.1038/s41589-023-01430-2. Epub 2023 Nov 6. Nat Chem Biol. 2023. PMID: 37932529 Free PMC article.
Identification of a second 16-hydroxytabersonine-O-methyltransferase suggests an evolutionary relationship between alkaloid and flavonoid metabolisms in Catharanthus roseus.
Lemos Cruz P, Carqueijeiro I, Koudounas K, Bomzan DP, Stander EA, Abdallah C, Kulagina N, Oudin A, Lanoue A, Giglioli-Guivarc'h N, Nagegowda DA, Papon N, Besseau S, Clastre M, Courdavault V. Lemos Cruz P, et al. Among authors: koudounas k. Protoplasma. 2023 Mar;260(2):607-624. doi: 10.1007/s00709-022-01801-x. Epub 2022 Aug 10. Protoplasma. 2023. PMID: 35947213
Tonoplast and Peroxisome Targeting of γ-tocopherol N-methyltransferase Homologs Involved in the Synthesis of Monoterpene Indole Alkaloids.
Koudounas K, Guirimand G, Hoyos LFR, Carqueijeiro I, Cruz PL, Stander E, Kulagina N, Perrin J, Oudin A, Besseau S, Lanoue A, Atehortùa L, St-Pierre B, Giglioli-Guivarc'h N, Papon N, O'Connor SE, Courdavault V. Koudounas K, et al. Plant Cell Physiol. 2022 Feb 15;63(2):200-216. doi: 10.1093/pcp/pcab160. Plant Cell Physiol. 2022. PMID: 35166361
30 results