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NRF2 activation in the heart induces glucose metabolic reprogramming and reduces cardiac dysfunction via upregulation of the pentose phosphate pathway.
Zoccarato A, Smyrnias I, Reumiller CM, Hafstad AD, Chong M, Richards DA, Santos CXC, Visnagri A, Verma S, Bromage DI, Zhang M, Zhang X, Sawyer G, Thompson R, Shah AM. Zoccarato A, et al. Among authors: hafstad ad. Cardiovasc Res. 2024 Dec 6:cvae250. doi: 10.1093/cvr/cvae250. Online ahead of print. Cardiovasc Res. 2024. PMID: 39657243
Guidelines on models of diabetic heart disease.
Heather LC, Hafstad AD, Halade GV, Harmancey R, Mellor KM, Mishra PK, Mulvihill EE, Nabben M, Nakamura M, Rider OJ, Ruiz M, Wende AR, Ussher JR. Heather LC, et al. Among authors: hafstad ad. Am J Physiol Heart Circ Physiol. 2022 Jul 1;323(1):H176-H200. doi: 10.1152/ajpheart.00058.2022. Epub 2022 Jun 3. Am J Physiol Heart Circ Physiol. 2022. PMID: 35657616 Free PMC article. Review.
Nox4 regulates InsP3 receptor-dependent Ca2+ release into mitochondria to promote cell survival.
Beretta M, Santos CX, Molenaar C, Hafstad AD, Miller CC, Revazian A, Betteridge K, Schröder K, Streckfuß-Bömeke K, Doroshow JH, Fleck RA, Su TP, Belousov VV, Parsons M, Shah AM. Beretta M, et al. Among authors: hafstad ad. EMBO J. 2020 Oct 1;39(19):e103530. doi: 10.15252/embj.2019103530. Epub 2020 Aug 10. EMBO J. 2020. PMID: 33001475 Free PMC article.
NADPH Oxidase 2 Mediates Myocardial Oxygen Wasting in Obesity.
Hafstad AD, Hansen SS, Lund J, Santos CXC, Boardman NT, Shah AM, Aasum E. Hafstad AD, et al. Antioxidants (Basel). 2020 Feb 19;9(2):171. doi: 10.3390/antiox9020171. Antioxidants (Basel). 2020. PMID: 32093119 Free PMC article.
30 results