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Page 1
Structure of Plasmodium vivaxN-myristoyltransferase with inhibitor IMP-1088: exploring an NMT inhibitor for antimalarial therapy.
Mendez A, Bolling C, Taylor S, Makumire S, Staker B, Reers A, Hammerson B, Mayclin SJ, Abendroth J, Lorimer DD, Edwards TE, Tate EW, Subramanian S, Bell AS, Myler PJ, Asojo OA, Chakafana G. Mendez A, et al. Among authors: reers a. Acta Crystallogr F Struct Biol Commun. 2025 Jan 1. doi: 10.1107/S2053230X24011348. Online ahead of print. Acta Crystallogr F Struct Biol Commun. 2025. PMID: 39655507
Ternary structure of Plasmodium vivaxN-myristoyltransferase with myristoyl-CoA and inhibitor IMP-0001173.
Bolling C, Mendez A, Taylor S, Makumire S, Reers A, Zigweid R, Subramanian S, Dranow DM, Staker B, Edwards TE, Tate EW, Bell AS, Myler PJ, Asojo OA, Chakafana G. Bolling C, et al. Among authors: reers a. Acta Crystallogr F Struct Biol Commun. 2024 Oct 1;80(Pt 10):269-277. doi: 10.1107/S2053230X24008604. Epub 2024 Sep 18. Acta Crystallogr F Struct Biol Commun. 2024. PMID: 39291304 Free PMC article.
Nucleolin acute degradation reveals novel functions in cell cycle progression and division in TNBC.
Mills J, Tessari A, Anastas V, Kumar DS, Rad NS, Lamba S, Cosentini I, Reers A, Zhu Z, Miles WO, Coppola V, Cocucci E, Magliery TJ, Shive H, Davies AE, Rizzotto L, Croce CM, Palmieri D. Mills J, et al. Among authors: reers a. bioRxiv [Preprint]. 2024 Jun 22:2024.06.17.599429. doi: 10.1101/2024.06.17.599429. bioRxiv. 2024. PMID: 38948867 Free PMC article. Preprint.
Atypical B cells consist of subsets with distinct functional profiles.
Reyes RA, Batugedara G, Dutta P, Reers AB, Garza R, Ssewanyana I, Jagannathan P, Feeney ME, Greenhouse B, Bol S, Ay F, Bunnik EM. Reyes RA, et al. Among authors: reers ab. iScience. 2023 Nov 20;26(12):108496. doi: 10.1016/j.isci.2023.108496. eCollection 2023 Dec 15. iScience. 2023. PMID: 38098745 Free PMC article.
Identification of and Structural Insights into Hit Compounds Targeting N-Myristoyltransferase for Cryptosporidium Drug Development.
Fenwick MK, Reers AR, Liu Y, Zigweid R, Sankaran B, Shin J, Hulverson MA, Hammerson B, Fernández Álvaro E, Myler PJ, Kaushansky A, Van Voorhis WC, Fan E, Staker BL. Fenwick MK, et al. Among authors: reers ar. ACS Infect Dis. 2023 Oct 13;9(10):1821-1833. doi: 10.1021/acsinfecdis.3c00151. Epub 2023 Sep 18. ACS Infect Dis. 2023. PMID: 37722671 Free PMC article.
Identification of Selective Inhibitors of Plasmodium N-Myristoyltransferase by High-Throughput Screening.
Harupa A, De Las Heras L, Colmenarejo G, Lyons-Abbott S, Reers A, Caballero Hernandez I, Chung CW, Charter D, Myler PJ, Fernández-Menéndez RM, Calderón F, Palomo S, Rodríguez B, Berlanga M, Herreros-Avilés E, Staker BL, Fernández Álvaro E, Kaushansky A. Harupa A, et al. Among authors: reers a. J Med Chem. 2020 Jan 23;63(2):591-600. doi: 10.1021/acs.jmedchem.9b01343. Epub 2020 Jan 8. J Med Chem. 2020. PMID: 31850752
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