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A minimal physiologically-based pharmacokinetic modeling platform to predict intratumor exposure and receptor occupancy of an anti-LAG-3 monoclonal antibody.
Michelet R, Petersson K, Huisman MC, Menke-van der Houven van Oordt CW, Miedema IHC, Thiele A, Montaseri G, Pérez-Pitarch A, Busse D. Michelet R, et al. Among authors: perez pitarch a. CPT Pharmacometrics Syst Pharmacol. 2024 Dec 9. doi: 10.1002/psp4.13285. Online ahead of print. CPT Pharmacometrics Syst Pharmacol. 2024. PMID: 39654382 Free article.
Discovery and Characterization of Brigimadlin, a Novel and Highly Potent MDM2-p53 Antagonist Suitable for Intermittent Dose Schedules.
Gollner A, Rudolph D, Weyer-Czernilofsky U, Baumgartinger R, Jung P, Weinstabl H, Ramharter J, Grempler R, Quant J, Rinnenthal J, Pérez Pitarch A, Golubovic B, Gerlach D, Bader G, Wetzel K, Otto S, Mandl C, Boehmelt G, McConnell DB, Kraut N, Sini P. Gollner A, et al. Among authors: perez pitarch a. Mol Cancer Ther. 2024 Dec 3;23(12):1689-1702. doi: 10.1158/1535-7163.MCT-23-0783. Mol Cancer Ther. 2024. PMID: 39259562 Free PMC article. Clinical Trial.
Effect of Sirolimus Exposure on the Need for Preemptive Antiviral Therapy for Cytomeglovirus Infection after Allogeneic Hematopoietic Stem Cell Transplantation.
Guglieri-Lopez B, Perez-Pitarch A, Garcia-Cadenas I, Gimenez E, Barba P, Rabella N, Hernandez-Boluda JC, Fox L, Valcarcel D, Esquirol A, Ferriols-Lisart R, Sierra J, Solano C, Navarro D, Martino R, Piñana JL. Guglieri-Lopez B, et al. Among authors: perez pitarch a. Biol Blood Marrow Transplant. 2019 May;25(5):1022-1030. doi: 10.1016/j.bbmt.2019.01.012. Epub 2019 Jan 10. Biol Blood Marrow Transplant. 2019. PMID: 30639821 Free article.
23 results