Ghiaur G - Search Results

1

The Dual PIM/FLT3 Inhibitor MEN1703 Combines Synergistically With Gilteritinib in FLT3-ITD-Mutant Acute Myeloid Leukaemia.

Zicari S, Merlino G, Paoli A, Fiascarelli A, Tunici P, Bisignano D, Belli F, Irrissuto C, Talucci S, Cirigliano E, Iannitto ML, Bigioni M, Bressan A, Brzózka K, Ghiaur G, Bellarosa D, Binaschi M. Zicari S, et al. Among authors: ghiaur g. J Cell Mol Med. 2024 Dec;28(23):e70235. doi: 10.1111/jcmm.70235. J Cell Mol Med. 2024. PMID: 39653657 Free PMC article.

2

All-trans retinoic acid synergizes with FLT3 inhibition to eliminate FLT3/ITD+ leukemia stem cells in vitro and in vivo.

Ma HS, Greenblatt SM, Shirley CM, Duffield AS, Bruner JK, Li L, Nguyen B, Jung E, Aplan PD, Ghiaur G, Jones RJ, Small D. Ma HS, et al. Among authors: ghiaur g. Blood. 2016 Jun 9;127(23):2867-78. doi: 10.1182/blood-2015-05-646786. Epub 2016 Apr 21. Blood. 2016. PMID: 27103744 Free PMC article.

3

Mechanisms of Resistance to FLT3 Inhibitors and the Role of the Bone Marrow Microenvironment.

Ghiaur G, Levis M. Ghiaur G, et al. Hematol Oncol Clin North Am. 2017 Aug;31(4):681-692. doi: 10.1016/j.hoc.2017.04.005. Epub 2017 May 18. Hematol Oncol Clin North Am. 2017. PMID: 28673395 Free PMC article. Review.

4

Role of CYP3A4 in bone marrow microenvironment-mediated protection of FLT3/ITD AML from tyrosine kinase inhibitors.

Chang YT, Hernandez D, Alonso S, Gao M, Su M, Ghiaur G, Levis MJ, Jones RJ. Chang YT, et al. Among authors: ghiaur g. Blood Adv. 2019 Mar 26;3(6):908-916. doi: 10.1182/bloodadvances.2018022921. Blood Adv. 2019. PMID: 30898762 Free PMC article.

5

Regulation of drug metabolizing enzymes in the leukaemic bone marrow microenvironment.

Su M, Chang YT, Hernandez D, Jones RJ, Ghiaur G. Su M, et al. Among authors: ghiaur g. J Cell Mol Med. 2019 Jun;23(6):4111-4117. doi: 10.1111/jcmm.14298. Epub 2019 Mar 28. J Cell Mol Med. 2019. PMID: 30920135 Free PMC article.

6

CCRL2 affects the sensitivity of myelodysplastic syndrome and secondary acute myeloid leukemia cells to azacitidine.

Karantanos T, Teodorescu P, Arvanitis M, Perkins B, Jain T, DeZern AE, Dalton WB, Christodoulou I, Paun BC, Varadhan R, Esteb C, Rajkhowa T, Bonifant C, Gondek LP, Levis MJ, Yegnasubramanian S, Ghiaur G, Jones RJ. Karantanos T, et al. Among authors: ghiaur g. Haematologica. 2023 Jul 1;108(7):1886-1899. doi: 10.3324/haematol.2022.281444. Haematologica. 2023. PMID: 36519323 Free PMC article.

7

All-Trans Retinoic Acid Activity in Acute Myeloid Leukemia: Role of Cytochrome P450 Enzyme Expression by the Microenvironment.

Su M, Alonso S, Jones JW, Yu J, Kane MA, Jones RJ, Ghiaur G. Su M, et al. Among authors: ghiaur g. PLoS One. 2015 Jun 5;10(6):e0127790. doi: 10.1371/journal.pone.0127790. eCollection 2015. PLoS One. 2015. PMID: 26047326 Free PMC article.

8

Translating leukemia stem cells into the clinical setting: Harmonizing the heterogeneity.

Yanagisawa B, Ghiaur G, Smith BD, Jones RJ. Yanagisawa B, et al. Among authors: ghiaur g. Exp Hematol. 2016 Dec;44(12):1130-1137. doi: 10.1016/j.exphem.2016.08.010. Epub 2016 Sep 28. Exp Hematol. 2016. PMID: 27693555 Free PMC article. Review.

9

Fibroblast dynamics as an in vitro screening platform for anti-fibrotic drugs in primary myelofibrosis.

Tomuleasa C, Selicean S, Gafencu G, Petrushev B, Pop L, Berce C, Jurj A, Trifa A, Rosu AM, Pasca S, Magdo L, Zdrenghea M, Dima D, Tanase A, Frinc I, Bojan A, Berindan-Neagoe I, Ghiaur G, Ciurea SO. Tomuleasa C, et al. Among authors: ghiaur g. J Cell Physiol. 2018 Jan;233(1):422-433. doi: 10.1002/jcp.25902. Epub 2017 May 23. J Cell Physiol. 2018. PMID: 28294327

10

PARP inhibitors in acute myeloid leukaemia therapy: How a synthetic lethality approach can be a valid therapeutic alternative.

Gafencu GA, Tomuleasa CI, Ghiaur G. Gafencu GA, et al. Among authors: ghiaur g. Med Hypotheses. 2017 Jul;104:30-34. doi: 10.1016/j.mehy.2017.05.015. Epub 2017 May 22. Med Hypotheses. 2017. PMID: 28673584

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