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Page 1
Revisiting the Plasmodium falciparum druggable genome using predicted structures and data mining.
Godinez-Macias KP, Chen D, Wallis JL, Siegel MG, Adam A, Bopp S, Carolino K, Coulson LB, Durst G, Thathy V, Esherick L, Farringer MA, Flannery EL, Forte B, Liu T, Magalhaes LG, Gupta AK, Istvan ES, Jiang T, Kumpornsin K, Lobb K, McLean K, Moura IMR, Okombo J, Payne NC, Plater A, Rao SPS, Siqueira-Neto JL, Somsen BA, Summers RL, Zhang R, Gilson MK, Gamo FJ, Campo B, Baragaña B, Duffy J, Gilbert IH, Lukens AK, Dechering KJ, Niles JC, McNamara CW, Cheng X, Birkholtz LM, Bronkhorst AW, Fidock DA, Wirth DF, Goldberg DE, Lee MCS, Winzeler EA. Godinez-Macias KP, et al. Among authors: winzeler ea. Res Sq [Preprint]. 2024 Nov 26:rs.3.rs-5412515. doi: 10.21203/rs.3.rs-5412515/v1. Res Sq. 2024. PMID: 39649165 Free PMC article. Preprint.
Antiplasmodial peptaibols act through membrane directed mechanisms.
Collins JE, Lee JW, Rocamora F, Saggu GS, Wendt KL, Pasaje CFA, Smick S, Santos NM, Paes R, Jiang T, Mittal N, Luth MR, Chin T, Chang H, McLellan JL, Morales-Hernandez B, Hanson KK, Niles JC, Desai SA, Winzeler EA, Cichewicz RH, Chakrabarti D. Collins JE, et al. Among authors: winzeler ea. Cell Chem Biol. 2024 Feb 15;31(2):312-325.e9. doi: 10.1016/j.chembiol.2023.10.025. Epub 2023 Nov 22. Cell Chem Biol. 2024. PMID: 37995692 Free PMC article.
Exploration and characterization of the antimalarial activity of cyclopropyl carboxamides that target the mitochondrial protein, cytochrome b.
Awalt JK, Su W, Nguyen W, Loi K, Jarman KE, Penington JS, Ramesh S, Fairhurst KJ, Yeo T, Park H, Uhlemann AC, Chandra Maity B, De N, Mukherjee P, Chakraborty A, Churchyard A, Famodimu MT, Delves MJ, Baum J, Mittal N, Winzeler EA, Papenfuss AT, Chowdury M, de Koning-Ward TF, Maier AG, van Dooren GG, Baud D, Brand S, Fidock DA, Jackson PF, Cowman AF, Dans MG, Sleebs BE. Awalt JK, et al. Among authors: winzeler ea. Eur J Med Chem. 2024 Dec 15;280:116921. doi: 10.1016/j.ejmech.2024.116921. Epub 2024 Oct 3. Eur J Med Chem. 2024. PMID: 39388903 Free PMC article.
Plasma Lipid Metabolites, Clinical Glycemic Predictors, and Incident Type 2 Diabetes.
Begzati A, Godinez-Macias KP, Long T, Watrous JD, Moranchel R, Kantz ED, Tuomilehto J, Havulinna AS, Niiranen TJ, Jousilahti P, Salomaa V, Yu B, Norby F, Rebholz CM, Selvin E, Winzeler EA, Cheng S, Alotaibi M, Goyal R, Ideker T, Jain M, Majithia AR. Begzati A, et al. Among authors: winzeler ea. Diabetes Care. 2025 Jan 6:dc242266. doi: 10.2337/dc24-2266. Online ahead of print. Diabetes Care. 2025. PMID: 39761415
Transforming the Health Research Workforce in Mozambique: Achievements of the Mozambique Institute for Health Education and Research (MIHER) over a 13‑Year Journey.
Noormahomed EV, Noormahomed S, Cossa M, Joyce N, Miambo RD, Sousa IM, Nhacupe N, Mussá T, Sacarlal J, Gouveia L, Ferrão LJ, Carrilho C, Ismail M, Smith D, Martin NK, Goyal R, Barrett KE, Afonso SS, Mandane A, Saíde A, Vintuar P, Singo B, Aleixo B, Injage L, Winzeler EA, Correia-de-Sá P, Martins MDRO, Ferrinho P, Patel S, Mocumbi AO, Bickler SW, Benson CA, Badaró R, Schooley RT. Noormahomed EV, et al. Among authors: winzeler ea. Ann Glob Health. 2024 Dec 9;90(1):78. doi: 10.5334/aogh.4528. eCollection 2024. Ann Glob Health. 2024. PMID: 39678200 Free PMC article.
Systematic in vitro evolution in Plasmodium falciparum reveals key determinants of drug resistance.
Luth MR, Godinez-Macias KP, Chen D, Okombo J, Thathy V, Cheng X, Daggupati S, Davies H, Dhingra SK, Economy JM, Edgar RCS, Gomez-Lorenzo MG, Istvan ES, Jado JC, LaMonte GM, Melillo B, Mok S, Narwal SK, Ndiaye T, Ottilie S, Palomo Diaz S, Park H, Peña S, Rocamora F, Sakata-Kato T, Small-Saunders JL, Summers RL, Tumwebaze PK, Vanaerschot M, Xia G, Yeo T, You A, Gamo FJ, Goldberg DE, Lee MCS, McNamara CW, Ndiaye D, Rosenthal PJ, Schreiber SL, Serra G, De Siqueira-Neto JL, Skinner-Adams TS, Uhlemann AC, Kato N, Lukens AK, Wirth DF, Fidock DA, Winzeler EA. Luth MR, et al. Among authors: winzeler ea. Science. 2024 Nov 29;386(6725):eadk9893. doi: 10.1126/science.adk9893. Epub 2024 Nov 29. Science. 2024. PMID: 39607932
218 results