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Integrins in the kidney - beyond the matrix.
Bock F, Li S, Pozzi A, Zent R. Bock F, et al. Nat Rev Nephrol. 2024 Dec 6. doi: 10.1038/s41581-024-00906-1. Online ahead of print. Nat Rev Nephrol. 2024. PMID: 39643697 Review.
Rac1 promotes kidney collecting duct integrity by limiting actomyosin activity.
Bock F, Elias BC, Dong X, Parekh DV, Mernaugh G, Viquez OM, Hassan A, Amara VR, Liu J, Brown KL, Terker AS, Chiusa M, Gewin LS, Fogo AB, Brakebusch CH, Pozzi A, Zent R. Bock F, et al. J Cell Biol. 2021 Nov 1;220(11):e202103080. doi: 10.1083/jcb.202103080. Epub 2021 Oct 14. J Cell Biol. 2021. PMID: 34647970 Free PMC article.
Ligand-independent integrin β1 signaling supports lung adenocarcinoma development.
Haake SM, Plosa EJ, Kropski JA, Venton LA, Reddy A, Bock F, Chang BT, Luna AJ, Nabukhotna K, Xu ZQ, Prather RA, Lee S, Tanjore H, Polosukhin VV, Viquez OM, Jones A, Luo W, Wilson MH, Rathmell WK, Massion PP, Pozzi A, Blackwell TS, Zent R. Haake SM, et al. Among authors: bock f. JCI Insight. 2022 Aug 8;7(15):e154098. doi: 10.1172/jci.insight.154098. JCI Insight. 2022. PMID: 35763345 Free PMC article.
Reversal of the renal hyperglycemic memory in diabetic kidney disease by targeting sustained tubular p21 expression.
Al-Dabet MM, Shahzad K, Elwakiel A, Sulaj A, Kopf S, Bock F, Gadi I, Zimmermann S, Rana R, Krishnan S, Gupta D, Manoharan J, Fatima S, Nazir S, Schwab C, Baber R, Scholz M, Geffers R, Mertens PR, Nawroth PP, Griffin JH, Keller M, Dockendorff C, Kohli S, Isermann B. Al-Dabet MM, et al. Among authors: bock f. Nat Commun. 2022 Aug 27;13(1):5062. doi: 10.1038/s41467-022-32477-9. Nat Commun. 2022. PMID: 36030260 Free PMC article.
Activated Protein C Ameliorates Renal Ischemia-Reperfusion Injury by Restricting Y-Box Binding Protein-1 Ubiquitination.
Dong W, Wang H, Shahzad K, Bock F, Al-Dabet MM, Ranjan S, Wolter J, Kohli S, Hoffmann J, Dhople VM, Zhu C, Lindquist JA, Esmon CT, Gröne E, Gröne HJ, Madhusudhan T, Mertens PR, Schlüter D, Isermann B. Dong W, et al. Among authors: bock f. J Am Soc Nephrol. 2015 Nov;26(11):2789-99. doi: 10.1681/ASN.2014080846. Epub 2015 May 26. J Am Soc Nephrol. 2015. PMID: 26015455 Free PMC article.
502 results