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Page 1
Human adult neurogenesis loss corresponds with cognitive decline during epilepsy progression.
Ammothumkandy A, Corona L, Ravina K, Wolseley V, Nelson J, Atai N, Abedi A, Jimenez N, Armacost M, D'Orazio LM, Zuverza-Chavarria V, Cayce A, McCleary C, Nune G, Kalayjian L, Lee DJ, Lee B, Chow RH, Heck C, Russin JJ, Liu CY, Smith JAD, Bonaguidi MA. Ammothumkandy A, et al. Among authors: d orazio lm. Cell Stem Cell. 2024 Dec 3:S1934-5909(24)00401-6. doi: 10.1016/j.stem.2024.11.002. Online ahead of print. Cell Stem Cell. 2024. PMID: 39642885 Free article.
Brain delivery of supplemental docosahexaenoic acid (DHA): A randomized placebo-controlled clinical trial.
Arellanes IC, Choe N, Solomon V, He X, Kavin B, Martinez AE, Kono N, Buennagel DP, Hazra N, Kim G, D'Orazio LM, McCleary C, Sagare A, Zlokovic BV, Hodis HN, Mack WJ, Chui HC, Harrington MG, Braskie MN, Schneider LS, Yassine HN. Arellanes IC, et al. Among authors: d orazio lm. EBioMedicine. 2020 Sep;59:102883. doi: 10.1016/j.ebiom.2020.102883. Epub 2020 Jul 17. EBioMedicine. 2020. PMID: 32690472 Free PMC article. Clinical Trial.
APOE4 leads to blood-brain barrier dysfunction predicting cognitive decline.
Montagne A, Nation DA, Sagare AP, Barisano G, Sweeney MD, Chakhoyan A, Pachicano M, Joe E, Nelson AR, D'Orazio LM, Buennagel DP, Harrington MG, Benzinger TLS, Fagan AM, Ringman JM, Schneider LS, Morris JC, Reiman EM, Caselli RJ, Chui HC, Tcw J, Chen Y, Pa J, Conti PS, Law M, Toga AW, Zlokovic BV. Montagne A, et al. Nature. 2020 May;581(7806):71-76. doi: 10.1038/s41586-020-2247-3. Epub 2020 Apr 29. Nature. 2020. PMID: 32376954 Free PMC article.
Blood-brain barrier breakdown is an early biomarker of human cognitive dysfunction.
Nation DA, Sweeney MD, Montagne A, Sagare AP, D'Orazio LM, Pachicano M, Sepehrband F, Nelson AR, Buennagel DP, Harrington MG, Benzinger TLS, Fagan AM, Ringman JM, Schneider LS, Morris JC, Chui HC, Law M, Toga AW, Zlokovic BV. Nation DA, et al. Nat Med. 2019 Feb;25(2):270-276. doi: 10.1038/s41591-018-0297-y. Epub 2019 Jan 14. Nat Med. 2019. PMID: 30643288 Free PMC article.
Cerebroarterial pulsatility and resistivity indices are associated with cognitive impairment and white matter hyperintensity in elderly subjects: A phase-contrast MRI study.
Pahlavian SH, Wang X, Ma S, Zheng H, Casey M, D'Orazio LM, Shao X, Ringman JM, Chui H, Wang DJ, Yan L. Pahlavian SH, et al. J Cereb Blood Flow Metab. 2021 Mar;41(3):670-683. doi: 10.1177/0271678X20927101. Epub 2020 Jun 5. J Cereb Blood Flow Metab. 2021. PMID: 32501154 Free PMC article.
Evaluation of Cerebral Blood Flow Measured by 3D PCASL as Biomarker of Vascular Cognitive Impairment and Dementia (VCID) in a Cohort of Elderly Latinx Subjects at Risk of Small Vessel Disease.
Jann K, Shao X, Ma SJ, Cen SY, D'Orazio L, Barisano G, Yan L, Casey M, Lamas J, Staffaroni AM, Kramer JH, Ringman JM, Wang DJJ. Jann K, et al. Front Neurosci. 2021 Jan 27;15:627627. doi: 10.3389/fnins.2021.627627. eCollection 2021. Front Neurosci. 2021. PMID: 33584191 Free PMC article.
Baseline Findings of PreventE4: A Double-Blind Placebo Controlled Clinical Trial Testing High Dose DHA in APOE4 Carriers before the Onset of Dementia.
Yassine HN, Arellanes IC, Mazmanian A, De La Cruz L, Martinez J, Contreras L, Kono N, Liu BS, Badie D, Bantugan MA, Grindon A, Urich T, D'Orazio L, Emmanuel BA, Chui HC, Mack WJ, Harrington MG, Braskie MN, Schneider LS. Yassine HN, et al. J Prev Alzheimers Dis. 2023;10(4):810-820. doi: 10.14283/jpad.2023.77. J Prev Alzheimers Dis. 2023. PMID: 37874103 Clinical Trial.
25 results