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135 results

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Page 1
Tumor-derived CCL2 drives tumor growth and immunosuppression in IDH1-mutant cholangiocarcinoma.
Zabransky DJ, Kartalia E, Lee JW, Leatherman JM, Charmsaz S, Young SE, Chhabra Y, Franch-Expósito S, Kang M, Maru S, Rastkari N, Davis M, Dalton WB, Oshima K, Baretti M, Azad NS, Jaffee EM, Yarchoan M. Zabransky DJ, et al. Among authors: leatherman jm. Hepatology. 2024 Dec 3. doi: 10.1097/HEP.0000000000001185. Online ahead of print. Hepatology. 2024. PMID: 39626209
Entinostat in combination with nivolumab in metastatic pancreatic ductal adenocarcinoma: a phase 2 clinical trial.
Baretti M, Danilova L, Durham JN, Betts CB, Cope L, Sidiropoulos DN, Tandurella JA, Charmsaz S, Gross N, Hernandez A, Ho WJ, Thoburn C, Walker R, Leatherman J, Mitchell S, Christmas B, Saeed A, Gaykalova DA, Yegnasubramanian S, Fertig EJ, Coussens LM, Yarchoan M, Jaffee E, Azad NS. Baretti M, et al. Among authors: leatherman j. Nat Commun. 2024 Nov 12;15(1):9801. doi: 10.1038/s41467-024-52528-7. Nat Commun. 2024. PMID: 39532835 Free PMC article. Clinical Trial.
Immunotherapy response induces divergent tertiary lymphoid structure morphologies in hepatocellular carcinoma.
Shu DH, Ho WJ, Kagohara LT, Girgis A, Shin SM, Danilova L, Lee JW, Sidiropoulos DN, Mitchell S, Munjal K, Howe K, Bendinelli KJ, Kartalia E, Qi H, Mo G, Montagne J, Leatherman JM, Lopez-Vidal TY, Zhu Q, Huff AL, Yuan X, Hernandez A, Coyne EM, Zaidi N, Zabransky DJ, Engle LL, Ogurtsova A, Baretti M, Laheru D, Durham JN, Wang H, Sunshine JC, Johnston RJ, Deutsch JS, Taube JM, Anders RA, Jaffee EM, Fertig EJ, Yarchoan M. Shu DH, et al. Among authors: leatherman jm. Nat Immunol. 2024 Nov;25(11):2110-2123. doi: 10.1038/s41590-024-01992-w. Epub 2024 Oct 25. Nat Immunol. 2024. PMID: 39455893
Immune-related events in individuals with solid tumors on immunotherapy associate with Th17 and Th2 signatures.
Kao CJ, Charmsaz S, Alden SL, Brancati M, Li HL, Balaji A, Munjal K, Howe K, Mitchell S, Leatherman J, Griffin E, Nakazawa M, Tsai HL, Danilova L, Thoburn C, Gizzi J, Gross NE, Hernandez A, Coyne EM, Shin SM, Babu JS, Apostol GW, Durham J, Christmas BJ, Konig MF, Lipson EJ, Naidoo J, Cappelli LC, Pabani A, Ged Y, Baretti M, Brahmer J, Hoffman-Censits J, Seiwert TY, Garonce-Hediger R, Guha A, Bansal S, Tang L, Jaffee EM, Chandler GS, Mohindra R, Ho WJ, Yarchoan M. Kao CJ, et al. Among authors: leatherman j. J Clin Invest. 2024 Aug 29;134(20):e176567. doi: 10.1172/JCI176567. J Clin Invest. 2024. PMID: 39403935 Free PMC article. Clinical Trial.
Spatial multi-omics reveal intratumoral humoral immunity niches associated with tertiary lymphoid structures in pancreatic cancer immunotherapy pathologic responders.
Sidiropoulos DN, Shin SM, Wetzel M, Girgis AA, Bergman D, Danilova L, Perikala S, Shu DH, Montagne JM, Deshpande A, Leatherman J, Dequiedt L, Jacobs V, Ogurtsova A, Mo G, Yuan X, Lvovs D, Stein-O'Brien G, Yarchoan M, Zhu Q, Harper EI, Weeraratna AT, Kiemen AL, Jaffee EM, Zheng L, Ho WJ, Anders RA, Fertig EJ, Kagohara LT. Sidiropoulos DN, et al. Among authors: leatherman j. bioRxiv [Preprint]. 2024 Sep 23:2024.09.22.613714. doi: 10.1101/2024.09.22.613714. bioRxiv. 2024. PMID: 39386736 Free PMC article. Preprint.
A new Neu-a syngeneic model of spontaneously metastatic HER2-positive breast cancer.
Baugh AG, Gonzalez E, Narumi VH, Kreger J, Liu Y, Rafie C, Castanon S, Jang J, Kagohara LT, Anastasiadou DP, Leatherman J, Armstrong T, Chan I, Karagiannis GS, Jaffee EM, MacLean A, Roussos Torres ET. Baugh AG, et al. Among authors: leatherman j. Clin Exp Metastasis. 2024 Oct;41(5):733-746. doi: 10.1007/s10585-024-10289-z. Epub 2024 May 8. Clin Exp Metastasis. 2024. PMID: 38717519 Free PMC article.
Headpulse measurement can reliably identify large-vessel occlusion stroke in prehospital suspected stroke patients: Results from the EPISODE-PS-COVID study.
Paxton JH, Keenan KJ, Wilburn JM, Wise SL, Klausner HA, Ball MT, Dunne RB, Kreitel KD, Morgan LF, Fales WD, Madhok D, Barazangi N, McLean ST, Cross K, Distenfield L, Sykes J, Lovoi P, Johnson B, Smith WS; EPISODE‐PS‐COVID Collaborators. Paxton JH, et al. Acad Emerg Med. 2024 Sep;31(9):848-859. doi: 10.1111/acem.14919. Epub 2024 Apr 21. Acad Emerg Med. 2024. PMID: 38643419
Entinostat, nivolumab and ipilimumab for women with advanced HER2-negative breast cancer: a phase Ib trial.
Roussos Torres ET, Ho WJ, Danilova L, Tandurella JA, Leatherman J, Rafie C, Wang C, Brufsky A, LoRusso P, Chung V, Yuan Y, Downs M, O'Connor A, Shin SM, Hernandez A, Engle EL, Piekarz R, Streicher H, Talebi Z, Rudek MA, Zhu Q, Anders RA, Cimino-Mathews A, Fertig EJ, Jaffee EM, Stearns V, Connolly RM. Roussos Torres ET, et al. Among authors: leatherman j. Nat Cancer. 2024 Jun;5(6):866-879. doi: 10.1038/s43018-024-00729-w. Epub 2024 Feb 14. Nat Cancer. 2024. PMID: 38355777 Clinical Trial.
135 results