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Page 1
RANK drives structured intestinal epithelial expansion during pregnancy.
Onji M, Sigl V, Lendl T, Novatchkova M, Ullate-Agote A, Andersson-Rolf A, Kozieradzki I, Koglgruber R, Pai TP, Lichtscheidl D, Nayak K, Zilbauer M, Carranza García NA, Sievers LK, Falk-Paulsen M, Cronin SJF, Hagelkruys A, Sawa S, Osborne LC, Rosenstiel P, Pasparakis M, Ruland J, Takayanagi H, Clevers H, Koo BK, Penninger JM. Onji M, et al. Among authors: sievers lk. Nature. 2025 Jan;637(8044):156-166. doi: 10.1038/s41586-024-08284-1. Epub 2024 Dec 4. Nature. 2025. PMID: 39633049 Free PMC article.
Selection of cross-reactive T cells by commensal and food-derived yeasts drives cytotoxic TH1 cell responses in Crohn's disease.
Martini GR, Tikhonova E, Rosati E, DeCelie MB, Sievers LK, Tran F, Lessing M, Bergfeld A, Hinz S, Nikolaus S, Kümpers J, Matysiak A, Hofmann P, Saggau C, Schneiders S, Kamps AK, Jacobs G, Lieb W, Maul J, Siegmund B, Seegers B, Hinrichsen H, Oberg HH, Wesch D, Bereswill S, Heimesaat MM, Rupp J, Kniemeyer O, Brakhage AA, Brunke S, Hube B, Aden K, Franke A, Iliev ID, Scheffold A, Schreiber S, Bacher P. Martini GR, et al. Among authors: sievers lk. Nat Med. 2023 Oct;29(10):2602-2614. doi: 10.1038/s41591-023-02556-5. Epub 2023 Sep 25. Nat Med. 2023. PMID: 37749331 Free PMC article.
Decreased Serum Tryptophan and Severe Ulcerative Damage of Colon Mucosa Identify Inflammatory Bowel Disease Patients With High Risk of Cytomegalovirus Colitis.
Rüsing S, Welz L, Pfitzer C, Harris DM, Röcken C, Rosenstiel P, Nikolaus S, Tran F, Schreiber S, Aden K, Sievers LK. Rüsing S, et al. Among authors: sievers lk. Clin Transl Gastroenterol. 2024 Aug 1;15(8):e00731. doi: 10.14309/ctg.0000000000000731. Clin Transl Gastroenterol. 2024. PMID: 38934504 Free PMC article.
Defective Atg16l1 in intestinal epithelial cells links to altered fecal microbiota and metabolic shifts during pregnancy in mice.
López-Agudelo VA, Falk-Paulsen M, Bharti R, Rehman A, Sommer F, Wacker EM, Ellinghaus D, Luzius A, Sievers LK, Liebeke M, Kaser A, Rosenstiel P. López-Agudelo VA, et al. Among authors: sievers lk. Gut Microbes. 2024 Jan-Dec;16(1):2429267. doi: 10.1080/19490976.2024.2429267. Epub 2024 Dec 2. Gut Microbes. 2024. PMID: 39620359 Free PMC article.
A metabolic constraint in the kynurenine pathway drives mucosal inflammation in IBD.
Welz L, Harris DM, Kim NM, Alsaadi AI, Wu Q, Oumari M, Taubenheim J, Volk V, Credido G, Koncina E, Mukherjee PK, Tran F, Sievers LK, Pavlidis P, Powell N, Rieder F, Letellier E, Waschina S, Kaleta C, Feuerhake F, Verstockt B, McReynolds MR, Rosenstiel P, Schreiber S, Aden K. Welz L, et al. Among authors: sievers lk. medRxiv [Preprint]. 2024 Aug 8:2024.08.08.24311598. doi: 10.1101/2024.08.08.24311598. medRxiv. 2024. PMID: 39211892 Free PMC article. Preprint.
Dynamic changes in extracellular vesicle-associated miRNAs elicited by ultrasound in inflammatory bowel disease patients.
Tran F, Scharmacher A, Baran N, Mishra N, Wozny M, Chavez SP, Bhardwaj A, Hinz S, Juzenas S, Bernardes JP, Sievers LK, Lessing M, Aden K, Lassen A, Bergfeld A, Weber HJ, Neas L, Vetrano S, Schreiber S, Rosenstiel P. Tran F, et al. Among authors: sievers lk. Sci Rep. 2024 May 13;14(1):10925. doi: 10.1038/s41598-024-61532-2. Sci Rep. 2024. PMID: 38740826 Free PMC article.
FixNCut: single-cell genomics through reversible tissue fixation and dissociation.
Jiménez-Gracia L, Marchese D, Nieto JC, Caratù G, Melón-Ardanaz E, Gudiño V, Roth S, Wise K, Ryan NK, Jensen KB, Hernando-Momblona X, Bernardes JP, Tran F, Sievers LK, Schreiber S, van den Berge M, Kole T, van der Velde PL, Nawijn MC, Rosenstiel P, Batlle E, Butler LM, Parish IA, Plummer J, Gut I, Salas A, Heyn H, Martelotto LG. Jiménez-Gracia L, et al. Among authors: sievers lk. Genome Biol. 2024 Mar 29;25(1):81. doi: 10.1186/s13059-024-03219-5. Genome Biol. 2024. PMID: 38553769 Free PMC article.
[Mirikizumab for ulcerative colitis].
Sievers LK, Schreiber S, Nitschmann S. Sievers LK, et al. Inn Med (Heidelb). 2023 Dec;64(12):1230-1231. doi: 10.1007/s00108-023-01592-0. Epub 2023 Oct 17. Inn Med (Heidelb). 2023. PMID: 37847261 German. No abstract available.
14 results