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Amelioration of Alzheimer's disease pathology by mitophagy inducers identified via machine learning and a cross-species workflow.
Xie C, Zhuang XX, Niu Z, Ai R, Lautrup S, Zheng S, Jiang Y, Han R, Gupta TS, Cao S, Lagartos-Donate MJ, Cai CZ, Xie LM, Caponio D, Wang WW, Schmauck-Medina T, Zhang J, Wang HL, Lou G, Xiao X, Zheng W, Palikaras K, Yang G, Caldwell KA, Caldwell GA, Shen HM, Nilsen H, Lu JH, Fang EF. Xie C, et al. Among authors: xiao x. Nat Biomed Eng. 2022 Jan;6(1):76-93. doi: 10.1038/s41551-021-00819-5. Epub 2022 Jan 6. Nat Biomed Eng. 2022. PMID: 34992270 Free PMC article.
PharmaBench: Enhancing ADMET benchmarks with large language models.
Niu Z, Xiao X, Wu W, Cai Q, Jiang Y, Jin W, Wang M, Yang G, Kong L, Jin X, Yang G, Chen H. Niu Z, et al. Among authors: xiao x. Sci Data. 2024 Sep 10;11(1):985. doi: 10.1038/s41597-024-03793-0. Sci Data. 2024. PMID: 39256394 Free PMC article.
NR1D1 Inhibition Enhances Autophagy and Mitophagy in Alzheimer's Disease Models.
Zhang SQ, Niu Z, Anisimov A, Shi F, Deng S, Xiao X, Cao SQ, Pan JP, Wang HL, Lagartos-Donate MJ, Bozbas NG, Wang PJ, Ai R, Li Y, Yang G, Lautrup S, Fang EF. Zhang SQ, et al. Among authors: xiao x. Aging Dis. 2025 Jan 14. doi: 10.14336/AD.2024.1654. Online ahead of print. Aging Dis. 2025. PMID: 39812544
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