Knappe C - Search Results

1

Tilting the Scales toward EGFR Mutant Selectivity: Expanding the Scope of Bivalent "Type V" Kinase Inhibitors.

Wittlinger F, Chitnis SP, Pham CD, Damghani T, Patel KB, Möllers M, Schaeffner IK, Abidakun OA, Deng MQ, Ogboo BC, Rasch A, Beyett TS, Buckley B, Feru F, Shaurova T, Knappe C, Eck MJ, Hershberger PA, Scott DA, Brandt AL, Laufer SA, Heppner DE. Wittlinger F, et al. Among authors: knappe c. J Med Chem. 2024 Dec 12;67(23):21438-21469. doi: 10.1021/acs.jmedchem.4c02311. Epub 2024 Dec 3. J Med Chem. 2024. PMID: 39626019

2

Determination of double bond positions in unsaturated fatty acids by pre-column derivatization with dimethyl and dipyridyl disulfide followed by LC-SWATH-MS analysis.

Olfert M, Knappe C, Sievers-Engler A, Masberg B, Lämmerhofer M. Olfert M, et al. Among authors: knappe c. Anal Bioanal Chem. 2024 Oct 5. doi: 10.1007/s00216-024-05542-z. Online ahead of print. Anal Bioanal Chem. 2024. PMID: 39367908

3

Triphenyl-Modified Mixed-Mode Stationary Phases With and Without Embedded Ion-Exchange Sites for High-Performance Liquid Chromatography.

Wolter M, Maalouf M, Janek M, Knappe C, Kramer M, Lämmerhofer M. Wolter M, et al. Among authors: knappe c. J Sep Sci. 2024 Dec;47(24):e70058. doi: 10.1002/jssc.70058. J Sep Sci. 2024. PMID: 39716842 Free PMC article.

4

Covalent Fragments Acting as Tyrosine Mimics for Mutant p53-Y220C Rescue by Nucleophilic Aromatic Substitution.

Klett T, Stahlecker J, Jaag S, Masberg B, Knappe C, Lämmerhofer M, Coles M, Stehle T, Boeckler FM. Klett T, et al. Among authors: knappe c. ACS Pharmacol Transl Sci. 2024 Nov 18;7(12):3984-3999. doi: 10.1021/acsptsci.4c00414. eCollection 2024 Dec 13. ACS Pharmacol Transl Sci. 2024. PMID: 39698266

5

Evaluation of a Covalent Library of Diverse Warheads (CovLib) Binding to JNK3, USP7, or p53.

Klett T, Schwer M, Ernst LN, Engelhardt MU, Jaag SJ, Masberg B, Knappe C, Lämmerhofer M, Gehringer M, Boeckler FM. Klett T, et al. Among authors: knappe c. Drug Des Devel Ther. 2024 Jul 1;18:2653-2679. doi: 10.2147/DDDT.S466829. eCollection 2024. Drug Des Devel Ther. 2024. PMID: 38974119 Free PMC article.

6

Isomer selectivity of one- and two-dimensional approaches of mixed-mode and hydrophilic interaction liquid chromatography coupled to tandem mass spectrometry for sugar phosphates of glycolysis and pentose phosphate pathways.

Su M, Serafimov K, Li P, Knappe C, Lämmerhofer M. Su M, et al. Among authors: knappe c. J Chromatogr A. 2023 Jan 11;1688:463727. doi: 10.1016/j.chroma.2022.463727. Epub 2022 Dec 18. J Chromatogr A. 2023. PMID: 36566570

7

Solving the retention time repeatability problem of hydrophilic interaction liquid chromatography.

Serafimov K, Knappe C, Li F, Sievers-Engler A, Lämmerhofer M. Serafimov K, et al. Among authors: knappe c. J Chromatogr A. 2024 Aug 16;1730:465060. doi: 10.1016/j.chroma.2024.465060. Epub 2024 Jun 8. J Chromatogr A. 2024. PMID: 38861823 Free article.

8

Two-dimensional sequential selective comprehensive chiral×reversed-phase liquid chromatography of synthetic phosphorothioate oligonucleotide diastereomers.

Li F, Knappe C, Carstensen N, Favorat E, Gao M, Holkenjans W, Hetzel T, Pell R, Lämmerhofer M. Li F, et al. Among authors: knappe c. J Chromatogr A. 2024 Aug 16;1730:465076. doi: 10.1016/j.chroma.2024.465076. Epub 2024 Jun 11. J Chromatogr A. 2024. PMID: 38879975 Free article.

9

Branched medium-chain fatty acid profiling and enantiomer separation of anteiso-forms of teicoplanin fatty acyl side chain RS3 using UHPLC-MS/MS with polysaccharide columns.

Geibel C, Olfert M, Knappe C, Serafimov K, Lämmerhofer M. Geibel C, et al. Among authors: knappe c. J Pharm Biomed Anal. 2023 Feb 5;224:115162. doi: 10.1016/j.jpba.2022.115162. Epub 2022 Nov 14. J Pharm Biomed Anal. 2023. PMID: 36423498

10

Non-enantioselective, enantioselective, and two-dimensional liquid chromatography coupled with tandem mass spectrometry for the study of stereochemical disposition of oxylipins in cGMP-regulated hemin-treated platelets.

Fu X, Knappe C, Rohlfing AK, Gawaz MP, Lämmerhofer M. Fu X, et al. Among authors: knappe c. J Pharm Biomed Anal. 2024 Sep 15;248:116328. doi: 10.1016/j.jpba.2024.116328. Epub 2024 Jun 26. J Pharm Biomed Anal. 2024. PMID: 38943819 Free article.

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