Cohen DE - Search Results

1

ChREBP-mediated up-regulation of Them1 coordinates thermogenesis with glycolysis and lipogenesis in response to chronic stress.

Xu X, Mendoza A, Krumm CS, Su S, Acuña M, Bare CJ, Holman CD, Cortopassi M, Nicholls HT, Dartigue V, Hollenberg AN, Lee AH, Hagen SJ, Cohen DE. Xu X, et al. Among authors: cohen de. Sci Signal. 2024 Dec 3;17(865):eadk7971. doi: 10.1126/scisignal.adk7971. Epub 2024 Dec 3. Sci Signal. 2024. PMID: 39626011

2

Preemptive Activation of the Integrated Stress Response Protects Mice From Diet-Induced Obesity and Insulin Resistance by Fibroblast Growth Factor 21 Induction.

Xu X, Krumm C, So JS, Bare CJ, Holman C, Gromada J, Cohen DE, Lee AH. Xu X, et al. Among authors: cohen de. Hepatology. 2018 Dec;68(6):2167-2181. doi: 10.1002/hep.30060. Epub 2018 Nov 5. Hepatology. 2018. PMID: 29698569 Free PMC article.

3

Thyroid hormone signaling promotes hepatic lipogenesis through the transcription factor ChREBP.

Mendoza A, Tang C, Choi J, Acuña M, Logan M, Martin AG, Al-Sowaimel L, Desai BN, Tenen DE, Jacobs C, Lyubetskaya A, Fu Y, Liu H, Tsai L, Cohen DE, Forrest D, Wilson AA, Hollenberg AN. Mendoza A, et al. Among authors: cohen de. Sci Signal. 2021 Nov 16;14(709):eabh3839. doi: 10.1126/scisignal.abh3839. Epub 2021 Nov 16. Sci Signal. 2021. PMID: 34784250 Free PMC article.

4

Mice lacking Pctp /StarD2 exhibit increased adaptive thermogenesis and enlarged mitochondria in brown adipose tissue.

Kang HW, Ribich S, Kim BW, Hagen SJ, Bianco AC, Cohen DE. Kang HW, et al. Among authors: cohen de. J Lipid Res. 2009 Nov;50(11):2212-21. doi: 10.1194/jlr.M900013-JLR200. Epub 2009 Jun 6. J Lipid Res. 2009. PMID: 19502644 Free PMC article.

5

Thioesterase superfamily member 2/Acyl-CoA thioesterase 13 (Them2/Acot13) regulates adaptive thermogenesis in mice.

Kang HW, Ozdemir C, Kawano Y, LeClair KB, Vernochet C, Kahn CR, Hagen SJ, Cohen DE. Kang HW, et al. Among authors: cohen de. J Biol Chem. 2013 Nov 15;288(46):33376-86. doi: 10.1074/jbc.M113.481408. Epub 2013 Sep 26. J Biol Chem. 2013. PMID: 24072708 Free PMC article.

6

Phosphatidylcholine transfer protein/StarD2 promotes microvesicular steatosis and liver injury in murine experimental steatohepatitis.

Nicholls HT, Hornick JL, Cohen DE. Nicholls HT, et al. Among authors: cohen de. Am J Physiol Gastrointest Liver Physiol. 2017 Jul 1;313(1):G50-G61. doi: 10.1152/ajpgi.00379.2016. Epub 2017 Apr 6. Am J Physiol Gastrointest Liver Physiol. 2017. PMID: 28385694 Free PMC article.

7

Regulation of fatty acid trafficking in liver by thioesterase superfamily member 1.

Desai A, Alves-Bezerra M, Li Y, Ozdemir C, Bare CJ, Li Y, Hagen SJ, Cohen DE. Desai A, et al. Among authors: cohen de. J Lipid Res. 2018 Feb;59(2):368-379. doi: 10.1194/jlr.M081455. Epub 2017 Dec 5. J Lipid Res. 2018. PMID: 29208699 Free PMC article.

8

Knockout of the X-linked Fgf13 in the hypothalamic paraventricular nucleus impairs sympathetic output to brown fat and causes obesity.

Sinden DS, Holman CD, Bare CJ, Sun X, Gade AR, Cohen DE, Pitt GS. Sinden DS, et al. Among authors: cohen de. FASEB J. 2019 Oct;33(10):11579-11594. doi: 10.1096/fj.201901178R. Epub 2019 Jul 24. FASEB J. 2019. PMID: 31339804 Free PMC article.

9

Dissociation of Adaptive Thermogenesis from Glucose Homeostasis in Microbiome-Deficient Mice.

Krisko TI, Nicholls HT, Bare CJ, Holman CD, Putzel GG, Jansen RS, Sun N, Rhee KY, Banks AS, Cohen DE. Krisko TI, et al. Among authors: cohen de. Cell Metab. 2020 Mar 3;31(3):592-604.e9. doi: 10.1016/j.cmet.2020.01.012. Epub 2020 Feb 20. Cell Metab. 2020. PMID: 32084379 Free PMC article.

10

Inducible hepatic expression of CREBH mitigates diet-induced obesity, insulin resistance, and hepatic steatosis in mice.

Krumm CS, Xu X, Bare CJ, Holman CD, Kersten S, Dow LE, Lee AH, Cohen DE. Krumm CS, et al. Among authors: cohen de. J Biol Chem. 2021 Jul;297(1):100815. doi: 10.1016/j.jbc.2021.100815. Epub 2021 May 21. J Biol Chem. 2021. PMID: 34023388 Free PMC article.

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