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Novel Benzimidazole Derivatives as Potent Inhibitors of Microsomal Prostaglandin E₂ Synthase 1 for the Potential Treatment of Inflammation, Pain, and Fever.

Ergül AG, Jordan PM, Dahlke P, Bal NB, Olğaç A, Uludağ O, Werz O, Çalışkan B, Banoglu E. Ergül AG, et al. J Med Chem. 2024 Dec 12;67(23):21143-21162. doi: 10.1021/acs.jmedchem.4c01883. Epub 2024 Dec 2. J Med Chem. 2024. PMID: 39622054

Quinazoline-4(3H)-one-7-carboxamide Derivatives as Human Soluble Epoxide Hydrolase Inhibitors with Developable 5-Lipoxygenase Activating Protein Inhibition.

Turanlı S, Ergül AG, Jordan PM, Olğaç A, Çalışkan B, Werz O, Banoglu E. Turanlı S, et al. Among authors: ergul ag. ACS Omega. 2022 Oct 5;7(41):36354-36365. doi: 10.1021/acsomega.2c04039. eCollection 2022 Oct 18. ACS Omega. 2022. PMID: 36278102 Free PMC article.

Novel potent benzimidazole-based microsomal prostaglandin E₂ synthase-1 (mPGES-1) inhibitors derived from BRP-201 that also inhibit leukotriene C₄ synthase.

Ergül AG, Maz TG, Kretzer C, Olğaç A, Jordan PM, Çalışkan B, Werz O, Banoglu E. Ergül AG, et al. Eur J Med Chem. 2022 Mar 5;231:114167. doi: 10.1016/j.ejmech.2022.114167. Epub 2022 Feb 1. Eur J Med Chem. 2022. PMID: 35152061

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