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Gene therapy for guanidinoacetate methyltransferase deficiency restores cerebral and myocardial creatine while resolving behavioral abnormalities.
Khoja S, Lambert J, Nitzahn M, Eliav A, Zhang Y, Tamboline M, Le CT, Nasser E, Li Y, Patel P, Zhuravka I, Lueptow LM, Tkachyova I, Xu S, Nissim I, Schulze A, Lipshutz GS. Khoja S, et al. Among authors: xu s. Mol Ther Methods Clin Dev. 2022 Mar 28;25:278-296. doi: 10.1016/j.omtm.2022.03.015. eCollection 2022 Jun 9. Mol Ther Methods Clin Dev. 2022. PMID: 35505663 Free PMC article.
A humanized monoclonal antibody targeting an ectonucleotidase rescues cardiac metabolism and heart function after myocardial infarction.
Li S, Tao B, Wan J, Montecino-Rodriguez E, Wang P, Ma F, Sun B, Gu Y, Ramadoss S, Su L, Sun Q, Hoeve JT, Stiles L, Collins J, van Dam RM, Tamboline M, Taschereau R, Shirihai O, Kitchen DB, Pellegrini M, Graeber T, Dorshkind K, Xu S, Deb A. Li S, et al. Among authors: xu s. Cell Rep Med. 2024 Nov 19;5(11):101795. doi: 10.1016/j.xcrm.2024.101795. Epub 2024 Oct 24. Cell Rep Med. 2024. PMID: 39454569 Free PMC article.
PPARγ-dependent remodeling of translational machinery in adipose progenitors is impaired in obesity.
De Siqueira MK, Li G, Zhao Y, Wang S, Ahn IS, Tamboline M, Hildreth AD, Larios J, Schcolnik-Cabrera A, Nouhi Z, Zhang Z, Tol MJ, Pandey V, Xu S, O'Sullivan TE, Mack JJ, Tontonoz P, Sallam T, Wohlschlegel JA, Hulea L, Xiao X, Yang X, Villanueva CJ. De Siqueira MK, et al. Among authors: xu s. Cell Rep. 2024 Dec 24;43(12):114945. doi: 10.1016/j.celrep.2024.114945. Epub 2024 Nov 22. Cell Rep. 2024. PMID: 39579770 Free article.
A Glucose-Responsive Glucagon-Micelle for the Prevention of Hypoglycemia.
Vinciguerra D, Rajalakshmi P S, Yang J, Georgiou PG, Snell K, Pesenti T, Collins J, Tamboline M, Xu S, van Dam RM, Messina KMM, Hevener AL, Maynard HD. Vinciguerra D, et al. Among authors: xu s. ACS Cent Sci. 2024 Oct 2;10(11):2036-2047. doi: 10.1021/acscentsci.4c00937. eCollection 2024 Nov 27. ACS Cent Sci. 2024. PMID: 39634211 Free PMC article.
Spatial mapping of mitochondrial networks and bioenergetics in lung cancer.
Han M, Bushong EA, Segawa M, Tiard A, Wong A, Brady MR, Momcilovic M, Wolf DM, Zhang R, Petcherski A, Madany M, Xu S, Lee JT, Poyurovsky MV, Olszewski K, Holloway T, Gomez A, John MS, Dubinett SM, Koehler CM, Shirihai OS, Stiles L, Lisberg A, Soatto S, Sadeghi S, Ellisman MH, Shackelford DB. Han M, et al. Among authors: xu s. Nature. 2023 Mar;615(7953):712-719. doi: 10.1038/s41586-023-05793-3. Epub 2023 Mar 15. Nature. 2023. PMID: 36922590 Free PMC article.
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