Ishikawa F - Search Results

1

Biosynthetic Incorporation of Non-native Aryl Acid Building Blocks into Peptide Products Using Engineered Adenylation Domains.

Ishikawa F, Nohara M, Miyanaga A, Kuramoto S, Miyano N, Asamizu S, Kudo F, Onaka H, Eguchi T, Tanabe G. Ishikawa F, et al. ACS Chem Biol. 2024 Dec 20;19(12):2569-2579. doi: 10.1021/acschembio.4c00663. Epub 2024 Dec 2. ACS Chem Biol. 2024. PMID: 39620357

2

An Engineered Aryl Acid Adenylation Domain with an Enlarged Substrate Binding Pocket.

Ishikawa F, Miyanaga A, Kitayama H, Nakamura S, Nakanishi I, Kudo F, Eguchi T, Tanabe G. Ishikawa F, et al. Angew Chem Int Ed Engl. 2019 May 20;58(21):6906-6910. doi: 10.1002/anie.201900318. Epub 2019 Apr 23. Angew Chem Int Ed Engl. 2019. PMID: 30945421

3

Probing the Compatibility of an Enzyme-Linked Immunosorbent Assay toward the Reprogramming of Nonribosomal Peptide Synthetase Adenylation Domains.

Ishikawa F, Nohara M, Takashima K, Tanabe G. Ishikawa F, et al. Chembiochem. 2020 Nov 2;21(21):3056-3061. doi: 10.1002/cbic.202000206. Epub 2020 Jul 17. Chembiochem. 2020. PMID: 32533653

4

Mutational Biosynthesis of Hitachimycin Analogs Controlled by the β-Amino Acid-Selective Adenylation Enzyme HitB.

Kudo F, Takahashi S, Miyanaga A, Nakazawa Y, Nishino K, Hayakawa Y, Kawamura K, Ishikawa F, Tanabe G, Iwai N, Nagumo Y, Usui T, Eguchi T. Kudo F, et al. Among authors: ishikawa f. ACS Chem Biol. 2021 Mar 19;16(3):539-547. doi: 10.1021/acschembio.1c00003. Epub 2021 Feb 24. ACS Chem Biol. 2021. PMID: 33625847

5

Biosynthetic diversification of non-ribosomal peptides through activity-based protein profiling of adenylation domains.

Ishikawa F, Tsukumo N, Morishita E, Asamizu S, Kusuhara S, Marumoto S, Takashima K, Onaka H, Tanabe G. Ishikawa F, et al. Chem Commun (Camb). 2023 Aug 1;59(62):9473-9476. doi: 10.1039/d3cc02633g. Chem Commun (Camb). 2023. PMID: 37477345

6

Proteolytic Regulation in the Biosynthesis of Natural Product Via a ClpP Protease System.

Ishikawa F, Uchida C, Tanabe G. Ishikawa F, et al. ACS Chem Biol. 2024 Aug 16;19(8):1794-1802. doi: 10.1021/acschembio.4c00304. Epub 2024 Aug 3. ACS Chem Biol. 2024. PMID: 39096241

7

Visualizing the Adenylation Activities and Protein-Protein Interactions of Aryl Acid Adenylating Enzymes.

Ishikawa F, Kasai S, Kakeya H, Tanabe G. Ishikawa F, et al. Chembiochem. 2017 Nov 16;18(22):2199-2204. doi: 10.1002/cbic.201700361. Epub 2017 Oct 11. Chembiochem. 2017. PMID: 28871667

8

Structural Basis of Protein-Protein Interactions between a trans-Acting Acyltransferase and Acyl Carrier Protein in Polyketide Disorazole Biosynthesis.

Miyanaga A, Ouchi R, Ishikawa F, Goto E, Tanabe G, Kudo F, Eguchi T. Miyanaga A, et al. Among authors: ishikawa f. J Am Chem Soc. 2018 Jun 27;140(25):7970-7978. doi: 10.1021/jacs.8b04162. Epub 2018 Jun 13. J Am Chem Soc. 2018. PMID: 29870659

9

Activity-Based Protein Profiling of Non-ribosomal Peptide Synthetases.

Ishikawa F, Tanabe G, Kakeya H. Ishikawa F, et al. Curr Top Microbiol Immunol. 2019;420:321-349. doi: 10.1007/82_2018_133. Curr Top Microbiol Immunol. 2019. PMID: 30178264 Review.

10

Chemical Strategies for Visualizing and Analyzing Endogenous Nonribosomal Peptide Synthetase (NRPS) Megasynthetases.

Ishikawa F, Tanabe G. Ishikawa F, et al. Chembiochem. 2019 Aug 16;20(16):2032-2040. doi: 10.1002/cbic.201900186. Epub 2019 Jul 22. Chembiochem. 2019. PMID: 31134733 Review.

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