Hinck CS - Search Results

1

The TGF-β mimic TGM4 achieves cell specificity through combinatorial surface co-receptor binding.

Singh SP, Smyth DJ, Cunningham KT, Mukundan A, Byeon CH, Hinck CS, White MPJ, Ciancia C, Wąsowska N, Sanders A, Jin R, White RF, Lilla S, Zanivan S, Schoenherr C, Inman GJ, van Dinther M, Ten Dijke P, Hinck AP, Maizels RM. Singh SP, et al. Among authors: hinck cs. EMBO Rep. 2025 Jan;26(1):218-244. doi: 10.1038/s44319-024-00323-2. Epub 2024 Nov 28. EMBO Rep. 2025. PMID: 39609640 Free PMC article.

2

Demonstration of differential quantitative requirements for NSF among multiple vesicle fusion pathways of GLUT4 using a dominant-negative ATPase-deficient NSF.

Chen X, Matsumoto H, Hinck CS, Al-Hasani H, St-Denis JF, Whiteheart SW, Cushman SW. Chen X, et al. Among authors: hinck cs. Biochem Biophys Res Commun. 2005 Jul 22;333(1):28-34. doi: 10.1016/j.bbrc.2005.05.075. Biochem Biophys Res Commun. 2005. PMID: 15935991

3

Activation of phenylalanine hydroxylase by phenylalanine does not require binding in the active site.

Roberts KM, Khan CA, Hinck CS, Fitzpatrick PF. Roberts KM, et al. Among authors: hinck cs. Biochemistry. 2014 Dec 16;53(49):7846-53. doi: 10.1021/bi501183x. Epub 2014 Dec 2. Biochemistry. 2014. PMID: 25453233 Free PMC article.

4

Mechanism of the Flavoprotein d-6-Hydroxynicotine Oxidase: Substrate Specificity, pH and Solvent Isotope Effects, and Roles of Key Active-Site Residues.

Fitzpatrick PF, Dougherty V, Subedi B, Quilantan J, Hinck CS, Lujan AI, Tormos JR. Fitzpatrick PF, et al. Among authors: hinck cs. Biochemistry. 2019 May 28;58(21):2534-2541. doi: 10.1021/acs.biochem.9b00297. Epub 2019 May 10. Biochemistry. 2019. PMID: 31046245 Free PMC article.

5

Mechanism of the Flavoprotein L-Hydroxynicotine Oxidase: Kinetic Mechanism, Substrate Specificity, Reaction Product, and Roles of Active-Site Residues.

Fitzpatrick PF, Chadegani F, Zhang S, Roberts KM, Hinck CS. Fitzpatrick PF, et al. Among authors: hinck cs. Biochemistry. 2016 Feb 2;55(4):697-703. doi: 10.1021/acs.biochem.5b01325. Epub 2016 Jan 15. Biochemistry. 2016. PMID: 26744768 Free PMC article.

6

Crystal structure of the human TbetaR2 ectodomain--TGF-beta3 complex.

Hart PJ, Deep S, Taylor AB, Shu Z, Hinck CS, Hinck AP. Hart PJ, et al. Among authors: hinck cs, hinck ap. Nat Struct Biol. 2002 Mar;9(3):203-8. doi: 10.1038/nsb766. Nat Struct Biol. 2002. PMID: 11850637

7

Cooperative assembly of TGF-beta superfamily signaling complexes is mediated by two disparate mechanisms and distinct modes of receptor binding.

Groppe J, Hinck CS, Samavarchi-Tehrani P, Zubieta C, Schuermann JP, Taylor AB, Schwarz PM, Wrana JL, Hinck AP. Groppe J, et al. Among authors: hinck cs, hinck ap. Mol Cell. 2008 Feb 1;29(2):157-68. doi: 10.1016/j.molcel.2007.11.039. Mol Cell. 2008. PMID: 18243111 Free article.

8

TbetaR-II discriminates the high- and low-affinity TGF-beta isoforms via two hydrogen-bonded ion pairs.

Baardsnes J, Hinck CS, Hinck AP, O'Connor-McCourt MD. Baardsnes J, et al. Among authors: hinck cs, hinck ap. Biochemistry. 2009 Mar 17;48(10):2146-55. doi: 10.1021/bi8019004. Biochemistry. 2009. PMID: 19161338 Free PMC article.

9

Characterization of the SRP68/72 interface of human signal recognition particle by systematic site-directed mutagenesis.

Iakhiaeva E, Hinck CS, Hinck AP, Zwieb C. Iakhiaeva E, et al. Among authors: hinck cs, hinck ap. Protein Sci. 2009 Oct;18(10):2183-95. doi: 10.1002/pro.232. Protein Sci. 2009. PMID: 19693936 Free PMC article.

10

A novel highly potent trivalent TGF-β receptor trap inhibits early-stage tumorigenesis and tumor cell invasion in murine Pten-deficient prostate glands.

Qin T, Barron L, Xia L, Huang H, Villarreal MM, Zwaagstra J, Collins C, Yang J, Zwieb C, Kodali R, Hinck CS, Kim SK, Reddick RL, Shu C, O'Connor-McCourt MD, Hinck AP, Sun LZ. Qin T, et al. Among authors: hinck cs, hinck ap. Oncotarget. 2016 Dec 27;7(52):86087-86102. doi: 10.18632/oncotarget.13343. Oncotarget. 2016. PMID: 27863384 Free PMC article.

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