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Page 1
Circulating tumor-reactive KIR+CD8+ T cells suppress anti-tumor immunity in patients with melanoma.
Lu BY, Lucca LE, Lewis W, Wang J, Nogueira CV, Heer S, Rayon-Estrada V, Axisa PP, Reeves SM, Buitrago-Pocasangre NC, Pham GH, Kojima ML, Wei W, Aizenbud L, Bacchiocchi A, Zhang L, Walewski JJ, Chiang V, Olino K, Clune J, Halaban R, Kluger Y, Coyle AJ, Kisielow J, Obermair FJ, Kluger HM, Hafler DA. Lu BY, et al. Among authors: nogueira cv. Nat Immunol. 2024 Nov 28. doi: 10.1038/s41590-024-02023-4. Online ahead of print. Nat Immunol. 2024. PMID: 39609626
The Vacuolar Pathway in Macrophages Plays a Major Role in Antigen Cross-Presentation Induced by the Pore-Forming Protein Sticholysin II Encapsulated Into Liposomes.
Cruz-Leal Y, Grubaugh D, Nogueira CV, Lopetegui-González I, Del Valle A, Escalona F, Laborde RJ, Alvarez C, Fernández LE, Starnbach MN, Higgins DE, Lanio ME. Cruz-Leal Y, et al. Among authors: nogueira cv. Front Immunol. 2018 Nov 5;9:2473. doi: 10.3389/fimmu.2018.02473. eCollection 2018. Front Immunol. 2018. PMID: 30455685 Free PMC article.
Sticholysins, pore-forming proteins from a marine anemone can induce maturation of dendritic cells through a TLR4 dependent-pathway.
Laborde RJ, Ishimura ME, Abreu-Butin L, Nogueira CV, Grubaugh D, Cruz-Leal Y, Luzardo MC, Fernández A, Mesa C, Pazos F, Álvarez C, Alonso ME, Starnbach MN, Higgins DE, Fernández LE, Longo-Maugéri IM, Lanio ME. Laborde RJ, et al. Among authors: nogueira cv. Mol Immunol. 2021 Mar;131:144-154. doi: 10.1016/j.molimm.2020.12.032. Epub 2021 Jan 6. Mol Immunol. 2021. PMID: 33422341
Novel Adjuvant Based on the Pore-Forming Protein Sticholysin II Encapsulated into Liposomes Effectively Enhances the Antigen-Specific CTL-Mediated Immune Response.
Laborde RJ, Sanchez-Ferras O, Luzardo MC, Cruz-Leal Y, Fernández A, Mesa C, Oliver L, Canet L, Abreu-Butin L, Nogueira CV, Tejuca M, Pazos F, Álvarez C, Alonso ME, Longo-Maugéri IM, Starnbach MN, Higgins DE, Fernández LE, Lanio ME. Laborde RJ, et al. Among authors: nogueira cv. J Immunol. 2017 Apr 1;198(7):2772-2784. doi: 10.4049/jimmunol.1600310. Epub 2017 Mar 3. J Immunol. 2017. PMID: 28258198 Free PMC article.
Sticholysin II shows similar immunostimulatory properties to LLO stimulating dendritic cells and MHC-I restricted T cell responses of heterologous antigen.
Del Valle A, Acosta-Rivero N, Laborde RJ, Cruz-Leal Y, Cabezas S, Luzardo MC, Alvarez C, Labrada M, Rodríguez A, Rodríguez GL, Raymond J, Nogueira CV, Grubaugh D, Fernández LE, Higgins D, Lanio ME. Del Valle A, et al. Among authors: nogueira cv. Toxicon. 2021 Sep;200:38-47. doi: 10.1016/j.toxicon.2021.06.020. Epub 2021 Jul 6. Toxicon. 2021. PMID: 34237340
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