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Circulating tumor-reactive KIR+CD8+ T cells suppress anti-tumor immunity in patients with melanoma.
Lu BY, Lucca LE, Lewis W, Wang J, Nogueira CV, Heer S, Rayon-Estrada V, Axisa PP, Reeves SM, Buitrago-Pocasangre NC, Pham GH, Kojima ML, Wei W, Aizenbud L, Bacchiocchi A, Zhang L, Walewski JJ, Chiang V, Olino K, Clune J, Halaban R, Kluger Y, Coyle AJ, Kisielow J, Obermair FJ, Kluger HM, Hafler DA. Lu BY, et al. Among authors: lucca le. Nat Immunol. 2024 Nov 28. doi: 10.1038/s41590-024-02023-4. Online ahead of print. Nat Immunol. 2024. PMID: 39609626
PD-1 marks dysfunctional regulatory T cells in malignant gliomas.
Lowther DE, Goods BA, Lucca LE, Lerner BA, Raddassi K, van Dijk D, Hernandez AL, Duan X, Gunel M, Coric V, Krishnaswamy S, Love JC, Hafler DA. Lowther DE, et al. Among authors: lucca le. JCI Insight. 2016 Apr 21;1(5):e85935. doi: 10.1172/jci.insight.85935. JCI Insight. 2016. PMID: 27182555 Free PMC article.
TIGIT signaling restores suppressor function of Th1 Tregs.
Lucca LE, Axisa PP, Singer ER, Nolan NM, Dominguez-Villar M, Hafler DA. Lucca LE, et al. JCI Insight. 2019 Feb 7;4(3):e124427. doi: 10.1172/jci.insight.124427. JCI Insight. 2019. PMID: 30728325 Free PMC article.
Differential expression of the T-cell inhibitor TIGIT in glioblastoma and MS.
Lucca LE, Lerner BA, Park C, DeBartolo D, Harnett B, Kumar VP, Ponath G, Raddassi K, Huttner A, Hafler DA, Pitt D. Lucca LE, et al. Neurol Neuroimmunol Neuroinflamm. 2020 Apr 8;7(3):e712. doi: 10.1212/NXI.0000000000000712. Print 2020 May 4. Neurol Neuroimmunol Neuroinflamm. 2020. PMID: 32269065 Free PMC article.
28 results