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Protocol of the IntenSify-Trial: An open-label phase I trial of the CYP3A inhibitor cobicistat and the cytostatics gemcitabine and nab-paclitaxel in patients with advanced stage or metastatic pancreatic ductal adenocarcinoma to evaluate the combination's pharmacokinetics, safety, and efficacy.
Hohmann N, Sprick MR, Pohl M, Ahmed A, Burhenne J, Kirchner M, Le Cornet L, Kratzmann M, Hajda J, Stenzinger A, Steindorf K, Delorme S, Schlemmer HP, Riethdorf S, van Schaik R, Pantel K, Siveke J, Seufferlein T, Jäger D, Haefeli WE, Trumpp A, Springfeld C. Hohmann N, et al. Among authors: pantel k. Clin Transl Sci. 2023 Dec;16(12):2483-2493. doi: 10.1111/cts.13661. Epub 2023 Nov 3. Clin Transl Sci. 2023. PMID: 37920921 Free PMC article.
Circulating tumor cell plasticity determines breast cancer therapy resistance via neuregulin 1-HER3 signaling.
Würth R, Donato E, Michel LL, Saini M, Becker L, Cheytan T, Doncevic D, Messmer T, Gutjahr E, Weber R, Klein C, Alborzinia H, Yildiz U, Vogel V, Hlevnjak M, Kozyulina P, Neuberth SJ, Schwerd-Kleine P, Jakab S, Pfarr N, Angeles AK, Laut AK, Karpova D, Falcone M, Hardt O, Theek B, Wagner CV, Becker M, Wagner S, Haselmayr M, Schmitt A, Müller-Tidow C, Riethdorf S, Pantel K, Zapatka M, Sültmann H, Herrmann C, Thewes V, Lichter P, Schneeweiss A, Sprick MR, Trumpp A. Würth R, et al. Among authors: pantel k. Nat Cancer. 2025 Jan 3. doi: 10.1038/s43018-024-00882-2. Online ahead of print. Nat Cancer. 2025. PMID: 39753722
Evaluation of S100A8/A9 and neutrophils as prognostic markers in metastatic melanoma patients under immune-checkpoint inhibition.
Melzer YF, Fergen NL, Mess C, Stadler JC, Geidel G, Schwietzer YA, Kött J, Pantel K, Schneider SW, Utikal J, Wladykowski E, Vidal-Y-Sy S, Bauer AT, Gebhardt C. Melzer YF, et al. Among authors: pantel k. Transl Oncol. 2024 Dec 18;52:102224. doi: 10.1016/j.tranon.2024.102224. Online ahead of print. Transl Oncol. 2024. PMID: 39700646 Free article.
Two decades of advances in clinical oncology - lessons learned and future directions.
Banerjee S, Booth CM, Bruera E, Büchler MW, Drilon A, Fry TJ, Ghobrial IM, Gianni L, Jain RK, Kroemer G, Llovet JM, Long GV, Pantel K, Pritchard-Jones K, Scher HI, Tabernero J, Weichselbaum RR, Weller M, Wu YL. Banerjee S, et al. Among authors: pantel k. Nat Rev Clin Oncol. 2024 Nov;21(11):771-780. doi: 10.1038/s41571-024-00945-4. Epub 2024 Oct 1. Nat Rev Clin Oncol. 2024. PMID: 39354161 No abstract available.
Plasma ctDNA as a Treatment Response Biomarker in Metastatic Cancers: Evaluation by the RECIST Working Group.
Wyatt AW, Litiere S, Bidard FC, Cabel L, Dyrskjøt L, Karlovich CA, Pantel K, Petrie J, Philip R, Andrews HS, Vellanki PJ, Tolmeijer SH, Villalobos Alberu X, Alfano C, Bogaerts J, Calvo E, Chen AP, Toledo RA, de Vries EGE, Seymour L, Laurie SA, Garralda E; RECIST ctDNA workshop group. Wyatt AW, et al. Among authors: pantel k. Clin Cancer Res. 2024 Nov 15;30(22):5034-5041. doi: 10.1158/1078-0432.CCR-24-1883. Clin Cancer Res. 2024. PMID: 39269996 Review.
KRAS and GNAS mutations in cell-free DNA and in circulating epithelial cells in patients with intraductal papillary mucinous neoplasms-an observational pilot study.
Nitschke C, Tölle M, Walter P, Meißner K, Goetz M, Kropidlowski J, Berger AW, Izbicki JR, Nickel F, Hackert T, Pantel K, Wikman H, Uzunoglu FG. Nitschke C, et al. Among authors: pantel k. Mol Oncol. 2024 Sep 1. doi: 10.1002/1878-0261.13719. Online ahead of print. Mol Oncol. 2024. PMID: 39219164 Free article.
682 results