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21 results

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Page 1
Integration of single cell omics with biobank data discovers trans effects of SREBF1 abdominal obesity risk variants on adipocyte expression of more than 100 genes.
Sukhatme MG, Kar A, Arasu UT, Lee SHT, Alvarez M, Garske KM, Gelev KZ, Rajkumar S, Das SS, Kaminska D, Männistö V, Peltoniemi H, Heinonen S, Säiläkivi U, Saarinen T, Juuti A, Pietiläinen KH, Pihlajamäki J, Kaikkonen MU, Pajukanta P. Sukhatme MG, et al. Among authors: garske km. medRxiv [Preprint]. 2024 Nov 23:2024.11.22.24317804. doi: 10.1101/2024.11.22.24317804. medRxiv. 2024. PMID: 39606332 Free PMC article. Preprint.
Single nucleus RNA-sequencing integrated into risk variant colocalization discovers 17 cell-type-specific abdominal obesity genes for metabolic dysfunction-associated steatotic liver disease.
Lee SHT, Garske KM, Arasu UT, Kar A, Miao Z, Alvarez M, Koka A, Darci-Maher N, Benhammou JN, Pan DZ, Örd T, Kaminska D, Männistö V, Heinonen S, Wabitsch M, Laakso M, Agopian VG, Pisegna JR, Pietiläinen KH, Pihlajamäki J, Kaikkonen MU, Pajukanta P. Lee SHT, et al. Among authors: garske km. EBioMedicine. 2024 Aug;106:105232. doi: 10.1016/j.ebiom.2024.105232. Epub 2024 Jul 10. EBioMedicine. 2024. PMID: 38991381 Free PMC article.
Age-dependent genes in adipose stem and precursor cells affect regulation of fat cell differentiation and link aging to obesity via cellular and genetic interactions.
Kar A, Alvarez M, Garske KM, Huang H, Lee SHT, Deal M, Das SS, Koka A, Jamal Z, Mohlke KL, Laakso M, Heinonen S, Pietiläinen KH, Pajukanta P. Kar A, et al. Among authors: garske km. Genome Med. 2024 Jan 31;16(1):19. doi: 10.1186/s13073-024-01291-x. Genome Med. 2024. PMID: 38297378 Free PMC article.
Characterizing the landscape of gene expression variance in humans.
Wolf S, Melo D, Garske KM, Pallares LF, Lea AJ, Ayroles JF. Wolf S, et al. Among authors: garske km. PLoS Genet. 2023 Jul 6;19(7):e1010833. doi: 10.1371/journal.pgen.1010833. eCollection 2023 Jul. PLoS Genet. 2023. PMID: 37410774 Free PMC article.
Adaptations to water stress and pastoralism in the Turkana of northwest Kenya.
Lea AJ, Caldas IV, Garske KM, Echwa J, Gurven M, Handley C, Kahumbu J, Kamau, Kinyua P, Lotukoi F, Lopurudoi A, Lowasa S, Mallarino R, Martins D, Messer PW, Miano C, Muhoya B, Peng J, Phung T, Rabinowitz JD, Roichman A, Siford R, Stone A, Oill AT, Mathew S, Wilson MA, Ayroles JF. Lea AJ, et al. Among authors: garske km. bioRxiv [Preprint]. 2023 Jan 19:2023.01.17.524066. doi: 10.1101/2023.01.17.524066. bioRxiv. 2023. PMID: 36711473 Free PMC article. Preprint.
Correction to: Identification of TBX15 as an adipose master trans regulator of abdominal obesity genes.
Pan DZ, Miao Z, Comenho C, Rajkumar S, Koka A, Lee SHT, Alvarez M, Kaminska D, Ko A, Sinsheimer JS, Mohlke KL, Mancuso N, Muñoz-Hernandez LL, Herrera-Hernandez M, Tusié-Luna MT, Aguilar-Salinas C, Pietiläinen KH, Pihlajamäki J, Laakso M, Garske KM, Pajukanta P. Pan DZ, et al. Among authors: garske km. Genome Med. 2021 Aug 30;13(1):139. doi: 10.1186/s13073-021-00954-3. Genome Med. 2021. PMID: 34461981 Free PMC article. No abstract available.
Identification of TBX15 as an adipose master trans regulator of abdominal obesity genes.
Pan DZ, Miao Z, Comenho C, Rajkumar S, Koka A, Lee SHT, Alvarez M, Kaminska D, Ko A, Sinsheimer JS, Mohlke KL, Mancuso N, Muñoz-Hernandez LL, Herrera-Hernandez M, Tusié-Luna MT, Aguilar-Salinas C, Pietiläinen KH, Pihlajamäki J, Laakso M, Garske KM, Pajukanta P. Pan DZ, et al. Among authors: garske km. Genome Med. 2021 Aug 2;13(1):123. doi: 10.1186/s13073-021-00939-2. Genome Med. 2021. PMID: 34340684 Free PMC article.
21 results