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Targeting GOF p53 and c-MYC through LZK Inhibition or Degradation Suppresses Head and Neck Tumor Growth.
Funk AL, Katerji M, Afifi M, Nyswaner K, Woodroofe CC, Edwards ZC, Lindberg E, Bergman KL, Gough NR, Rubin MR, Karpińska K, Trotter EW, Dash S, Ries AL, James A, Robinson CM, Difilippantonio S, Karim BO, Chang TC, Chen L, Xu X, Doroshow JH, Ahel I, Marusiak AA, Swenson RE, Cappell SD, Brognard J. Funk AL, et al. Among authors: chang tc. bioRxiv [Preprint]. 2024 Nov 20:2024.11.19.623840. doi: 10.1101/2024.11.19.623840. bioRxiv. 2024. PMID: 39605563 Free PMC article. Preprint.
Safety, Antitumor Activity, and Biomarker Analysis in a Phase I Trial of the Once-daily Wee1 Inhibitor Adavosertib (AZD1775) in Patients with Advanced Solid Tumors.
Takebe N, Naqash AR, O'Sullivan Coyne G, Kummar S, Do K, Bruns A, Juwara L, Zlott J, Rubinstein L, Piekarz R, Sharon E, Streicher H, Mittra A, Miller SB, Ji J, Wilsker D, Kinders RJ, Parchment RE, Chen L, Chang TC, Das B, Mugundu G, Doroshow JH, Chen AP. Takebe N, et al. Among authors: chang tc. Clin Cancer Res. 2021 Jul 15;27(14):3834-3844. doi: 10.1158/1078-0432.CCR-21-0329. Epub 2021 Apr 16. Clin Cancer Res. 2021. PMID: 33863809 Free PMC article. Clinical Trial.
Pharmacodynamic effects of the PARP inhibitor talazoparib (MDV3800, BMN 673) in patients with BRCA-mutated advanced solid tumors.
Mittra A, Coyne GHOS, Zlott J, Kummar S, Meehan R, Rubinstein L, Juwara L, Wilsker D, Ji J, Miller B, Navas T, Ferry-Galow KV, Voth AR, Chang TC, Jiwani S, Parchment RE, Doroshow JH, Chen AP. Mittra A, et al. Among authors: chang tc. Cancer Chemother Pharmacol. 2024 Mar;93(3):177-189. doi: 10.1007/s00280-023-04600-0. Epub 2023 Nov 27. Cancer Chemother Pharmacol. 2024. PMID: 38010394 Free PMC article. Clinical Trial.
Lactiplantibacillus plantarum 1008 Promotes Reproductive Function and Cognitive Activity in Aged Male Mice with High-Fat-Diet-Induced Obesity by Altering Metabolic Parameters and Alleviating Testicular Oxidative Damage, Inflammation and Apoptosis.
Liu CY, Tsai TY, Liu TH, Chang TC, Chen YW, Tsao CW. Liu CY, et al. Among authors: chang tc. Antioxidants (Basel). 2024 Dec 9;13(12):1498. doi: 10.3390/antiox13121498. Antioxidants (Basel). 2024. PMID: 39765826 Free PMC article.
MedShapeNet - a large-scale dataset of 3D medical shapes for computer vision.
Li J, Zhou Z, Yang J, Pepe A, Gsaxner C, Luijten G, Qu C, Zhang T, Chen X, Li W, Wodzinski M, Friedrich P, Xie K, Jin Y, Ambigapathy N, Nasca E, Solak N, Melito GM, Vu VD, Memon AR, Schlachta C, De Ribaupierre S, Patel R, Eagleson R, Chen X, Mächler H, Kirschke JS, de la Rosa E, Christ PF, Li HB, Ellis DG, Aizenberg MR, Gatidis S, Küstner T, Shusharina N, Heller N, Andrearczyk V, Depeursinge A, Hatt M, Sekuboyina A, Löffler MT, Liebl H, Dorent R, Vercauteren T, Shapey J, Kujawa A, Cornelissen S, Langenhuizen P, Ben-Hamadou A, Rekik A, Pujades S, Boyer E, Bolelli F, Grana C, Lumetti L, Salehi H, Ma J, Zhang Y, Gharleghi R, Beier S, Sowmya A, Garza-Villarreal EA, Balducci T, Angeles-Valdez D, Souza R, Rittner L, Frayne R, Ji Y, Ferrari V, Chatterjee S, Dubost F, Schreiber S, Mattern H, Speck O, Haehn D, John C, Nürnberger A, Pedrosa J, Ferreira C, Aresta G, Cunha A, Campilho A, Suter Y, Garcia J, Lalande A, Vandenbossche V, Van Oevelen A, Duquesne K, Mekhzoum H, Vandemeulebroucke J, Audenaert E, Krebs C, van Leeuwen T, Vereecke E, Heidemeyer H, Röhrig R, Hölzle F, Badeli V, Krieger K, Gunzer M, Chen J, van Meegdenburg T, Dada A, Balzer M, Fragemann J, Jonske F, Rempe M, Malorodov S,… See abstract for full author list ➔ Li J, et al. Among authors: chang tc. Biomed Tech (Berl). 2024 Dec 30. doi: 10.1515/bmt-2024-0396. Online ahead of print. Biomed Tech (Berl). 2024. PMID: 39733351
Reply to: Accurate Determinants of Outcome in ALL.
Chang TC, Chen W, Qu C, Cheng Z, Elsayed A, Pounds SB, Shago M, Rabin KR, Raetz EA, Devidas M, Cheng C, Angiolillo A, Baviskar P, Borowitz M, Burke MJ, Carroll A, Carroll WL, Chen IM, Harvey R, Heerema N, Iacobucci I, Wang JR, Jeha S, Larsen E, Mattano L, Maloney K, Pui CH, Ramirez NC, Salzer W, Willman C, Winick N, Wood B, Hunger SP, Wu G, Mullighan CG, Loh ML. Chang TC, et al. J Clin Oncol. 2024 Dec 23:JCO2402335. doi: 10.1200/JCO-24-02335. Online ahead of print. J Clin Oncol. 2024. PMID: 39715469 No abstract available.
1,448 results