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Page 1
Multi-stage-mixing to create a core-then-shell structure improves DNA-loaded lipid nanoparticles' transfection by orders of magnitude.
Nong J, Gong X, Dang QM, Tiwari S, Patel M, Wu J, Hanna A, Park WJ, Atochina-Vasserman EN, Huang HT, Marcos-Contreras OA, Morris-Blanco KC, Miner JJ, Weissman D, Muzykantov VR, Gupta K, Issadore D, Myerson JW, Wang Z, Brenner JS. Nong J, et al. Among authors: myerson jw. bioRxiv [Preprint]. 2024 Nov 15:2024.11.12.623321. doi: 10.1101/2024.11.12.623321. bioRxiv. 2024. PMID: 39605450 Free PMC article. Preprint.
Systems approaches to design of targeted therapeutic delivery.
Myerson JW, Brenner JS, Greineder CF, Muzykantov VR. Myerson JW, et al. Wiley Interdiscip Rev Syst Biol Med. 2015 Sep-Oct;7(5):253-65. doi: 10.1002/wsbm.1304. Epub 2015 May 6. Wiley Interdiscip Rev Syst Biol Med. 2015. PMID: 25946066 Free PMC article. Review.
Red blood cell-hitchhiking boosts delivery of nanocarriers to chosen organs by orders of magnitude.
Brenner JS, Pan DC, Myerson JW, Marcos-Contreras OA, Villa CH, Patel P, Hekierski H, Chatterjee S, Tao JQ, Parhiz H, Bhamidipati K, Uhler TG, Hood ED, Kiseleva RY, Shuvaev VS, Shuvaeva T, Khoshnejad M, Johnston I, Gregory JV, Lahann J, Wang T, Cantu E, Armstead WM, Mitragotri S, Muzykantov V. Brenner JS, et al. Among authors: myerson jw. Nat Commun. 2018 Jul 11;9(1):2684. doi: 10.1038/s41467-018-05079-7. Nat Commun. 2018. PMID: 29992966 Free PMC article.
Unintended effects of drug carriers: Big issues of small particles.
Parhiz H, Khoshnejad M, Myerson JW, Hood E, Patel PN, Brenner JS, Muzykantov VR. Parhiz H, et al. Among authors: myerson jw. Adv Drug Deliv Rev. 2018 May;130:90-112. doi: 10.1016/j.addr.2018.06.023. Epub 2018 Jul 3. Adv Drug Deliv Rev. 2018. PMID: 30149885 Free PMC article. Review.
Combining vascular targeting and the local first pass provides 100-fold higher uptake of ICAM-1-targeted vs untargeted nanocarriers in the inflamed brain.
Marcos-Contreras OA, Brenner JS, Kiseleva RY, Zuluaga-Ramirez V, Greineder CF, Villa CH, Hood ED, Myerson JW, Muro S, Persidsky Y, Muzykantov VR. Marcos-Contreras OA, et al. Among authors: myerson jw. J Control Release. 2019 May 10;301:54-61. doi: 10.1016/j.jconrel.2019.03.008. Epub 2019 Mar 11. J Control Release. 2019. PMID: 30871995 Free PMC article.
Selective targeting of nanomedicine to inflamed cerebral vasculature to enhance the blood-brain barrier.
Marcos-Contreras OA, Greineder CF, Kiseleva RY, Parhiz H, Walsh LR, Zuluaga-Ramirez V, Myerson JW, Hood ED, Villa CH, Tombacz I, Pardi N, Seliga A, Mui BL, Tam YK, Glassman PM, Shuvaev VV, Nong J, Brenner JS, Khoshnejad M, Madden T, Weissmann D, Persidsky Y, Muzykantov VR. Marcos-Contreras OA, et al. Among authors: myerson jw. Proc Natl Acad Sci U S A. 2020 Feb 18;117(7):3405-3414. doi: 10.1073/pnas.1912012117. Epub 2020 Jan 31. Proc Natl Acad Sci U S A. 2020. PMID: 32005712 Free PMC article.
Targeting drug delivery in the vascular system: Focus on endothelium.
Glassman PM, Myerson JW, Ferguson LT, Kiseleva RY, Shuvaev VV, Brenner JS, Muzykantov VR. Glassman PM, et al. Among authors: myerson jw. Adv Drug Deliv Rev. 2020;157:96-117. doi: 10.1016/j.addr.2020.06.013. Epub 2020 Jun 21. Adv Drug Deliv Rev. 2020. PMID: 32579890 Free PMC article. Review.
Monoclonal antibody 2C5 specifically targets neutrophil extracellular traps.
Mendes LP, Rostamizadeh K, Gollomp K, Myerson JW, Marcos-Contreras OA, Zamora M, Luther E, Brenner JS, Filipczak N, Li X, Torchilin VP. Mendes LP, et al. Among authors: myerson jw. MAbs. 2020 Jan-Dec;12(1):1850394. doi: 10.1080/19420862.2020.1850394. MAbs. 2020. PMID: 33323006 Free PMC article.
Supramolecular arrangement of protein in nanoparticle structures predicts nanoparticle tropism for neutrophils in acute lung inflammation.
Myerson JW, Patel PN, Rubey KM, Zamora ME, Zaleski MH, Habibi N, Walsh LR, Lee YW, Luther DC, Ferguson LT, Marcos-Contreras OA, Glassman PM, Mazaleuskaya LL, Johnston I, Hood ED, Shuvaeva T, Wu J, Zhang HY, Gregory JV, Kiseleva RY, Nong J, Grosser T, Greineder CF, Mitragotri S, Worthen GS, Rotello VM, Lahann J, Muzykantov VR, Brenner JS. Myerson JW, et al. Nat Nanotechnol. 2022 Jan;17(1):86-97. doi: 10.1038/s41565-021-00997-y. Epub 2021 Nov 18. Nat Nanotechnol. 2022. PMID: 34795440 Free PMC article.
50 results