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59 results

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A large-scale CRISPR screen reveals context-specific genetic regulation of retinal ganglion cell regeneration.
Emmerich K, Hageter J, Hoang T, Lyu P, Sharrock AV, Ceisel A, Thierer J, Chunawala Z, Nimmagadda S, Palazzo I, Matthews F, Zhang L, White DT, Rodriguez C, Graziano G, Marcos P, May A, Mulligan T, Reibman B, Saxena MT, Ackerley DF, Qian J, Blackshaw S, Horstick E, Mumm JS. Emmerich K, et al. Among authors: mumm js. Development. 2024 Aug 1;151(15):dev202754. doi: 10.1242/dev.202754. Epub 2024 Aug 12. Development. 2024. PMID: 39007397 Free PMC article.
Molecular regulation of retinal regeneration is context specific.
Emmerich K, Hageter J, Hoang T, Lyu P, Sharrock AV, Ceisel A, Thierer J, Chunawala Z, Nimmagadda S, Palazzo I, Matthews F, Zhang L, White DT, Rodriquez C, Graziano G, Marcos P, May A, Mulligan T, Reibman B, Saxena MT, Ackerley DF, Qian J, Blackshaw S, Horstick E, Mumm JS. Emmerich K, et al. Among authors: mumm js. bioRxiv [Preprint]. 2023 Nov 21:2023.11.20.567904. doi: 10.1101/2023.11.20.567904. bioRxiv. 2023. PMID: 38045256 Free PMC article. Preprint.
A metagenomic library cloning strategy that promotes high-level expression of captured genes to enable efficient functional screening.
Rich MH, Sharrock AV, Mulligan TS, Matthews F, Brown AS, Lee-Harwood HR, Williams EM, Copp JN, Little RF, Francis JJB, Horvat CN, Stevenson LJ, Owen JG, Saxena MT, Mumm JS, Ackerley DF. Rich MH, et al. Among authors: mumm js. Cell Chem Biol. 2023 Dec 21;30(12):1680-1691.e6. doi: 10.1016/j.chembiol.2023.10.001. Epub 2023 Oct 27. Cell Chem Biol. 2023. PMID: 37898120 Free PMC article.
Transcriptomic comparison of two selective retinal cell ablation paradigms in zebrafish reveals shared and cell-specific regenerative responses.
Emmerich K, Walker SL, Wang G, White DT, Ceisel A, Wang F, Teng Y, Chunawala Z, Graziano G, Nimmagadda S, Saxena MT, Qian J, Mumm JS. Emmerich K, et al. Among authors: mumm js. PLoS Genet. 2023 Oct 11;19(10):e1010905. doi: 10.1371/journal.pgen.1010905. eCollection 2023 Oct. PLoS Genet. 2023. PMID: 37819938 Free PMC article.
Retinal ganglion cell repopulation for vision restoration in optic neuropathy: a roadmap from the RReSTORe Consortium.
Soucy JR, Aguzzi EA, Cho J, Gilhooley MJ, Keuthan C, Luo Z, Monavarfeshani A, Saleem MA, Wang XW, Wohlschlegel J; RReSTORe Consortium; Baranov P, Di Polo A, Fortune B, Gokoffski KK, Goldberg JL, Guido W, Kolodkin AL, Mason CA, Ou Y, Reh TA, Ross AG, Samuels BC, Welsbie D, Zack DJ, Johnson TV. Soucy JR, et al. Mol Neurodegener. 2023 Sep 21;18(1):64. doi: 10.1186/s13024-023-00655-y. Mol Neurodegener. 2023. PMID: 37735444 Free PMC article. Review.
An inducible model of chronic hyperglycemia.
Tucker TR, Knitter CA, Khoury DM, Eshghi S, Tran S, Sharrock AV, Wiles TJ, Ackerley DF, Mumm JS, Parsons MJ. Tucker TR, et al. Among authors: mumm js. Dis Model Mech. 2023 Aug 1;16(8):dmm050215. doi: 10.1242/dmm.050215. Epub 2023 Aug 4. Dis Model Mech. 2023. PMID: 37401381 Free PMC article.
59 results