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Novel Uveal Melanoma Patient-Derived Organoid Models Recapitulate Human Disease to Support Translational Research.
Dalvin LA, Andrews-Pfannkoch CM, Miley DR, Hogenson TL, Erickson SA, Malpotra S, Anderson KJ, Omer ME, Almada LL, Zhang C, Li H, Salomao DR, Shields CL, Lally SE, Malsch RM, Armitage JA, Holmes HL, Romero MF, Fautsch MP, Markovic SN, Fernandez-Zapico ME. Dalvin LA, et al. Among authors: fernandez zapico me. Invest Ophthalmol Vis Sci. 2024 Nov 4;65(13):60. doi: 10.1167/iovs.65.13.60. Invest Ophthalmol Vis Sci. 2024. PMID: 39601636 Free PMC article.
Tumor-derived GLI1 promotes remodeling of the immune tumor microenvironment in melanoma.
Giammona A, De Vellis C, Crivaro E, Maresca L, Amoriello R, Ricci F, Anichini G, Pietrobono S, Pease DR, Fernandez-Zapico ME, Ballerini C, Stecca B. Giammona A, et al. Among authors: fernandez zapico me. J Exp Clin Cancer Res. 2024 Aug 2;43(1):214. doi: 10.1186/s13046-024-03138-0. J Exp Clin Cancer Res. 2024. PMID: 39090759 Free PMC article.
KRAS Promotes GLI2-Dependent Transcription during Pancreatic Carcinogenesis.
Sigafoos AN, Tolosa EJ, Carr RM, Fernandez-Barrena MG, Almada LL, Pease DR, Hogenson TL, Raja Arul GL, Mousavi F, Sen S, Vera RE, Marks DL, Flores LF, LaRue-Nolan KC, Wu C, Bamlet WR, Vrabel AM, Sicotte H, Schenk EL, Smyrk TC, Zhang L, Rabe KG, Oberg AL, Zaphiropoulos PG, Chevet E, Graham RP, Hagen CE, di Magliano MP, Elsawa SF, Pin CL, Mao J, McWilliams RR, Fernandez-Zapico ME. Sigafoos AN, et al. Among authors: fernandez zapico me. Cancer Res Commun. 2024 Jul 1;4(7):1677-1689. doi: 10.1158/2767-9764.CRC-23-0464. Cancer Res Commun. 2024. PMID: 38896052 Free PMC article.
PFKFB3 controls acinar IP3R-mediated Ca2+ overload to regulate acute pancreatitis severity.
Zhang T, Chen S, Li L, Jin Y, Liu S, Liu Z, Shi F, Xie L, Guo P, Cannon AC, Ergashev A, Yao H, Huang C, Zhang B, Wu L, Sun H, Chen S, Shan Y, Yu Z, Tolosa EJ, Liu J, Fernandez-Zapico ME, Ma F, Chen G. Zhang T, et al. Among authors: fernandez zapico me. JCI Insight. 2024 May 23;9(13):e169481. doi: 10.1172/jci.insight.169481. JCI Insight. 2024. PMID: 38781030 Free PMC article.
Reconstitution of human PDAC using primary cells reveals oncogenic transcriptomic features at tumor onset.
Xu Y, Nipper MH, Dominguez AA, Ye Z, Akanuma N, Lopez K, Deng JJ, Arenas D, Sanchez A, Sharkey FE, Court CM, Singhi AD, Wang H, Fernandez-Zapico ME, Sun LZ, Zheng S, Chen Y, Liu J, Wang P. Xu Y, et al. Among authors: fernandez zapico me. Nat Commun. 2024 Jan 27;15(1):818. doi: 10.1038/s41467-024-45097-2. Nat Commun. 2024. PMID: 38280869 Free PMC article.
Tumor Explants Elucidate a Cascade of Paracrine SHH, WNT, and VEGF Signals Driving Pancreatic Cancer Angiosuppression.
Hasselluhn MC, Decker-Farrell AR, Vlahos L, Thomas DH, Curiel-Garcia A, Maurer HC, Wasko UN, Tomassoni L, Sastra SA, Palermo CF, Dalton TC, Ma A, Li F, Tolosa EJ, Hibshoosh H, Fernandez-Zapico ME, Muir A, Califano A, Olive KP. Hasselluhn MC, et al. Among authors: fernandez zapico me. Cancer Discov. 2024 Feb 8;14(2):348-361. doi: 10.1158/2159-8290.CD-23-0240. Cancer Discov. 2024. PMID: 37966260 Free PMC article.
Ectopic expression of DOCK8 regulates lysosome-mediated pancreatic tumor cell invasion.
Gutierrez-Ruiz OL, Johnson KM, Krueger EW, Nooren RE, Cruz-Reyes N, Heppelmann CJ, Hogenson TL, Fernandez-Zapico ME, McNiven MA, Razidlo GL. Gutierrez-Ruiz OL, et al. Among authors: fernandez zapico me. Cell Rep. 2023 Sep 26;42(9):113042. doi: 10.1016/j.celrep.2023.113042. Epub 2023 Aug 30. Cell Rep. 2023. PMID: 37651233 Free PMC article.
177 results