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Transforming growth factor-beta2 suppresses collagen cleavage in cultured human osteoarthritic cartilage, reduces expression of genes associated with chondrocyte hypertrophy and degradation, and increases prostaglandin E(2) production.
Tchetina EV, Antoniou J, Tanzer M, Zukor DJ, Poole AR. Tchetina EV, et al. Among authors: antoniou j. Am J Pathol. 2006 Jan;168(1):131-40. doi: 10.2353/ajpath.2006.050369. Am J Pathol. 2006. PMID: 16400016 Free PMC article.
Prostaglandin PGE2 at very low concentrations suppresses collagen cleavage in cultured human osteoarthritic articular cartilage: this involves a decrease in expression of proinflammatory genes, collagenases and COL10A1, a gene linked to chondrocyte hypertrophy.
Tchetina EV, Di Battista JA, Zukor DJ, Antoniou J, Poole AR. Tchetina EV, et al. Among authors: antoniou j. Arthritis Res Ther. 2007;9(4):R75. doi: 10.1186/ar2273. Arthritis Res Ther. 2007. PMID: 17683641 Free PMC article.
Short Link N promotes disc repair in a rabbit model of disc degeneration.
Mwale F, Masuda K, Grant MP, Epure LM, Kato K, Miyazaki S, Cheng K, Yamada J, Bae WC, Muehleman C, Roughley PJ, Antoniou J. Mwale F, et al. Among authors: antoniou j. Arthritis Res Ther. 2018 Aug 29;20(1):201. doi: 10.1186/s13075-018-1625-9. Arthritis Res Ther. 2018. PMID: 30157962 Free PMC article.
226 results