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Thiadiazolidinone (TDZD) Analogs Inhibit Aggregation-Mediated Pathology in Diverse Neurodegeneration Models, and Extend C. elegans Life- and Healthspan.
Kakraba S, Ayyadevara S, Mainali N, Balasubramaniam M, Bowroju S, Penthala NR, Atluri R, Barger SW, Griffin ST, Crooks PA, Shmookler Reis RJ. Kakraba S, et al. Among authors: balasubramaniam m. Pharmaceuticals (Basel). 2023 Oct 20;16(10):1498. doi: 10.3390/ph16101498. Pharmaceuticals (Basel). 2023. PMID: 37895969 Free PMC article.
A Novel Microtubule-Binding Drug Attenuates and Reverses Protein Aggregation in Animal Models of Alzheimer's Disease.
Kakraba S, Ayyadevara S, Penthala NR, Balasubramaniam M, Ganne A, Liu L, Alla R, Bommagani SB, Barger SW, Griffin WST, Crooks PA, Shmookler Reis RJ. Kakraba S, et al. Among authors: balasubramaniam m. Front Mol Neurosci. 2019 Dec 12;12:310. doi: 10.3389/fnmol.2019.00310. eCollection 2019. Front Mol Neurosci. 2019. PMID: 31920540 Free PMC article.
Ezetimibe Lowers Risk of Alzheimer's and Related Dementias over Sevenfold, Reducing Aggregation in Model Systems by Inhibiting 14-3-3G::Hexokinase Interaction.
Ganne A, Mainali N, Balasubramaniam M, Atluri R, Pahal S, Asante J, Nagel C, Vallurupalli S, Shmookler Reis RJ, Ayyadevara S. Ganne A, et al. Among authors: balasubramaniam m. Aging Biol. 2024;2:20240028. doi: 10.59368/agingbio.20240028. Epub 2024 Jun 26. Aging Biol. 2024. PMID: 39263528 Free PMC article.
221 results