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Staggered immunization with mRNA vaccines encoding SARS-CoV-2 polymerase or spike antigens broadens the T cell epitope repertoire.
Abt ER, Lam AK, Noguchi M, Rashid K, McLaughlin J, Teng PL, Tran W, Cheng D, Nesterenko PA, Mao Z, Creech AL, Burton Sojo G, Jeyachandran AV, Tam YK, Henley JE, Comai L, Pardi N, Arumugaswami V, Witte ON, Radu CG, Wu TT. Abt ER, et al. Among authors: witte on. Proc Natl Acad Sci U S A. 2024 Dec 3;121(49):e2406332121. doi: 10.1073/pnas.2406332121. Epub 2024 Nov 26. Proc Natl Acad Sci U S A. 2024. PMID: 39589869 Free PMC article.
HLA-A02:01 restricted T cell receptors against the highly conserved SARS-CoV-2 polymerase cross-react with human coronaviruses.
Nesterenko PA, McLaughlin J, Tsai BL, Burton Sojo G, Cheng D, Zhao D, Mao Z, Bangayan NJ, Obusan MB, Su Y, Ng RH, Chour W, Xie J, Li YR, Lee D, Noguchi M, Carmona C, Phillips JW, Kim JT, Yang L, Heath JR, Boutros PC, Witte ON. Nesterenko PA, et al. Among authors: witte on. Cell Rep. 2021 Dec 28;37(13):110167. doi: 10.1016/j.celrep.2021.110167. Epub 2021 Dec 10. Cell Rep. 2021. PMID: 34919800 Free PMC article.
Physical and in silico immunopeptidomic profiling of a cancer antigen prostatic acid phosphatase reveals targets enabling TCR isolation.
Mao Z, Nesterenko PA, McLaughlin J, Deng W, Burton Sojo G, Cheng D, Noguchi M, Chour W, DeLucia DC, Finton KA, Qin Y, Obusan MB, Tran W, Wang L, Bangayan NJ, Ta L, Chen CC, Seet CS, Crooks GM, Phillips JW, Heath JR, Strong RK, Lee JK, Wohlschlegel JA, Witte ON. Mao Z, et al. Among authors: witte on. Proc Natl Acad Sci U S A. 2022 Aug 2;119(31):e2203410119. doi: 10.1073/pnas.2203410119. Epub 2022 Jul 25. Proc Natl Acad Sci U S A. 2022. PMID: 35878026 Free PMC article.
T cell chemotaxis to lysophosphatidylcholine through the G2A receptor.
Radu CG, Yang LV, Riedinger M, Au M, Witte ON. Radu CG, et al. Among authors: witte on. Proc Natl Acad Sci U S A. 2004 Jan 6;101(1):245-50. doi: 10.1073/pnas.2536801100. Epub 2003 Dec 17. Proc Natl Acad Sci U S A. 2004. PMID: 14681556 Free PMC article.
Sustained suppression of Bcr-Abl-driven lymphoid leukemia by microRNA mimics.
McLaughlin J, Cheng D, Singer O, Lukacs RU, Radu CG, Verma IM, Witte ON. McLaughlin J, et al. Among authors: witte on. Proc Natl Acad Sci U S A. 2007 Dec 18;104(51):20501-6. doi: 10.1073/pnas.0710532105. Epub 2007 Dec 13. Proc Natl Acad Sci U S A. 2007. PMID: 18079287 Free PMC article.
384 results