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Page 1
Structure of Plasmodium vivaxN-myristoyltransferase with inhibitor IMP-1088: exploring an NMT inhibitor for antimalarial therapy.
Mendez A, Bolling C, Taylor S, Makumire S, Staker B, Reers A, Hammerson B, Mayclin SJ, Abendroth J, Lorimer DD, Edwards TE, Tate EW, Subramanian S, Bell AS, Myler PJ, Asojo OA, Chakafana G. Mendez A, et al. Among authors: abendroth j. Acta Crystallogr F Struct Biol Commun. 2025 Jan 1;81(Pt 1):1-10. doi: 10.1107/S2053230X24011348. Epub 2025 Jan 1. Acta Crystallogr F Struct Biol Commun. 2025. PMID: 39655507 Free PMC article.
Exquisite selectivity of griselimycin extends to beta subunit of DNA polymerases from Gram-negative bacterial pathogens.
Fenwick MK, Pierce PG, Abendroth J, Barrett KF, Barrett LK, Bowatte K, Choi R, Chun I, Conrady DG, Craig JK, Dranow DM, Hammerson B, Higgins T, Lorimer DD, Lukat P, Mayclin SJ, Hewitt SN, Peng YP, Shanbhogue A, Smutney H, Stigliano MZZ, Tillery LM, Udell HS, Wallace EG, DeRocher AE, Phan IQ, Staker BL, Subramanian S, Van Voorhis WC, Blankenfeldt W, Müller R, Edwards TE, Myler PJ. Fenwick MK, et al. Among authors: abendroth j. Commun Biol. 2024 Dec 5;7(1):1622. doi: 10.1038/s42003-024-07175-5. Commun Biol. 2024. PMID: 39639052 Free PMC article.
Discovery of UCB9386: A Potent, Selective, and Brain-Penetrant Nuak1 Inhibitor Suitable for In Vivo Pharmacological Studies.
Poullennec KG, Jnoff E, Abendroth J, Bhuma N, Calmiano M, Calmus L, Cardenas A, Courade JP, Delatour C, Hall A, de Haro T, Delker SL, Demaude T, Gaikwad N, Ghavate D, Gholap AR, Kierkowicz M, Le Mestre R, Van Hijfte N, Verheijden S, Vernerova K, De Wever V, Waghmode N. Poullennec KG, et al. Among authors: abendroth j. J Med Chem. 2024 Dec 12;67(23):20879-20910. doi: 10.1021/acs.jmedchem.4c01237. Epub 2024 Nov 26. J Med Chem. 2024. PMID: 39588908
Structures of Brucella ovis leucine-, isoleucine-, valine-, threonine- and alanine-binding protein reveal a conformationally flexible peptide-binding cavity.
Chakafana G, Boswell R, Chandler A, Jackson KA, Neblett S, Postal T, Subramanian S, Abendroth J, Myler PJ, Asojo OA. Chakafana G, et al. Among authors: abendroth j. Acta Crystallogr F Struct Biol Commun. 2024 Sep 1;80(Pt 9):193-199. doi: 10.1107/S2053230X24007027. Epub 2024 Aug 23. Acta Crystallogr F Struct Biol Commun. 2024. PMID: 39177244 Free PMC article.
Structural and functional characterization of FabG4 from Mycolicibacterium smegmatis.
Ran X, Parikh P, Abendroth J, Arakaki TL, Clifton MC, Edwards TE, Lorimer DD, Mayclin S, Staker BL, Myler P, McLaughlin KJ. Ran X, et al. Among authors: abendroth j. Acta Crystallogr F Struct Biol Commun. 2024 Apr 1;80(Pt 4):82-91. doi: 10.1107/S2053230X2400356X. Epub 2024 Apr 24. Acta Crystallogr F Struct Biol Commun. 2024. PMID: 38656226
Multidimensional Spectroscopy of Nuclear Spin Clusters in Diamond.
Herb K, Segawa TF, Völker LA, Abendroth JM, Janitz E, Zhu T, Degen CL. Herb K, et al. Among authors: abendroth jm. Phys Rev Lett. 2024 Mar 29;132(13):133002. doi: 10.1103/PhysRevLett.132.133002. Phys Rev Lett. 2024. PMID: 38613260
Characterization of an Acinetobacter baumannii Monofunctional Phosphomethylpyrimidine Kinase That Is Inhibited by Pyridoxal Phosphate.
De Vitto H, Belfon KKJ, Sharma N, Toay S, Abendroth J, Dranow DM, Lukacs CM, Choi R, Udell HS, Willis S, Barrera G, Beyer O, Li TD, Hicks KA, Torelli AT, French JB. De Vitto H, et al. Among authors: abendroth j. Biochemistry. 2024 Feb 2:10.1021/acs.biochem.3c00640. doi: 10.1021/acs.biochem.3c00640. Online ahead of print. Biochemistry. 2024. PMID: 38306231
140 results