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163 results

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Macrophages and nociceptor neurons form a sentinel unit around fenestrated capillaries to defend the synovium from circulating immune challenge.
Hasegawa T, Lee CYC, Hotchen AJ, Fleming A, Singh R, Suzuki K, Yuzaki M, Watanabe M, Birch MA, McCaskie AW, Lénárt N, Tóth K, Dénes Á, Liu Z, Ginhoux F, Richoz N, Clatworthy MR. Hasegawa T, et al. Among authors: clatworthy mr. Nat Immunol. 2024 Dec;25(12):2270-2283. doi: 10.1038/s41590-024-02011-8. Epub 2024 Nov 25. Nat Immunol. 2024. PMID: 39587345 Free PMC article.
Profiling immune cell tissue niches in the spatial -omics era.
Lee CYC, McCaffrey J, McGovern D, Clatworthy MR. Lee CYC, et al. Among authors: clatworthy mr. J Allergy Clin Immunol. 2024 Nov 8:S0091-6749(24)01178-3. doi: 10.1016/j.jaci.2024.11.001. Online ahead of print. J Allergy Clin Immunol. 2024. PMID: 39522655 Free article. Review.
The IBEX Knowledge-Base: Achieving more together with open science.
Radtke AJ, Anidi I, Arakkal L, Arroyo-Mejias A, Beuschel RT, Börner K, Chu CJ, Clark B, Clatworthy MR, Colautti J, Croteau J, Denha S, Dever R, Dutra WO, Fritzsche S, Fullam S, Gerner MY, Gola A, Gollob KJ, Hernandez JM, Hor JL, Ichise H, Jing Z, Jonigk D, Kandov E, Kastenmüller W, Koenig JFE, Kothurkar A, Kreins AY, Lamborn I, Lin Y, Luciano Pereira Morais K, Lunich A, Luz JCS, MacDonald RB, Makranz C, Maltez VI, Moriaty RV, Ocampo-Godinez JM, Olyntho VM, Padhan K, Remmert K, Richoz N, Schrom EC, Shang W, Shi L, Shih RM, Speranza E, Stierli S, Teichmann SA, Veres TZ, Vierhout M, Wachter BT, Wade-Vallance AK, Williams M, Zangger N, Germain RN, Yaniv Z. Radtke AJ, et al. Among authors: clatworthy mr. ArXiv [Preprint]. 2024 Jul 26:arXiv:2407.19059v1. ArXiv. 2024. PMID: 39398203 Free PMC article. Preprint.
Neutrophil extracellular traps protect the kidney from ascending infection and are required for a positive leukocyte dipstick test.
Stewart AP, Loudon KW, Routledge M, Lee CYC, Trotter P, Richoz N, Gillman E, Antrobus R, Mccaffrey J, Posner D, Conway Morris A, Karet Frankl FE, Clatworthy MR. Stewart AP, et al. Among authors: clatworthy mr. Sci Transl Med. 2024 Sep 25;16(766):eadh5090. doi: 10.1126/scitranslmed.adh5090. Epub 2024 Sep 25. Sci Transl Med. 2024. PMID: 39321268
Multifocal, multiphenotypic tumours arising from an MTOR mutation acquired in early embryogenesis.
Pacyna CN, Anandapadamanaban M, Loudon KW, Hay IM, Perisic O, Li R, Byrne M, Allen L, Roberts K, Hooks Y, Warren AY, Stewart GD, Clatworthy MR, Teichmann SA, Behjati S, Campbell PJ, Williams RL, Mitchell TJ. Pacyna CN, et al. Among authors: clatworthy mr. Oncogene. 2024 Oct;43(44):3268-3276. doi: 10.1038/s41388-024-03137-7. Epub 2024 Sep 13. Oncogene. 2024. PMID: 39271965 Free PMC article.
Chronic social defeat stress induces meningeal neutrophilia via type I interferon signaling.
Kigar SL, Lynall ME, DePuyt AE, Atkinson R, Sun VH, Samuels JD, Eassa NE, Poffenberger CN, Lehmann ML, Listwak SJ, Livak F, Elkahloun AG, Clatworthy MR, Bullmore ET, Herkenham M. Kigar SL, et al. Among authors: clatworthy mr. bioRxiv [Preprint]. 2024 Aug 31:2024.08.30.610447. doi: 10.1101/2024.08.30.610447. bioRxiv. 2024. PMID: 39257811 Free PMC article. Preprint.
Study protocol for a randomised, phase II, double-blind, experimental medicine study of obinutuzumab versus rituximab in ANCA-associated vasculitis: ObiVas.
McGovern DP, McClure ME, Coates M, Bond S, Martinez Del Pero M, Mynard K, Lee J, Smith RM, Jayne DR, Clatworthy MR, Jones RB; ObiVas Investigators. McGovern DP, et al. Among authors: clatworthy mr. BMJ Open. 2024 Jul 17;14(7):e083277. doi: 10.1136/bmjopen-2023-083277. BMJ Open. 2024. PMID: 39019638 Free PMC article.
Patient-derived organoid biobank identifies epigenetic dysregulation of intestinal epithelial MHC-I as a novel mechanism in severe Crohn's Disease.
Dennison TW, Edgar RD, Payne F, Nayak KM, Ross ADB, Cenier A, Glemas C, Giachero F, Foster AR, Harris R, Kraiczy J, Salvestrini C, Stavrou G, Torrente F, Brook K, Trayers C, Elmentaite R, Youssef G, Tél B, Winton DJ, Skoufou-Papoutsaki N, Adler S, Bufler P, Azabdaftari A, Jenke A, G N, Thomas N, Miele E, Al-Mohammad A, Guarda G, Kugathasan S, Venkateswaran S, Clatworthy MR, Castro-Dopico T, Suchanek O, Strisciuglio C, Gasparetto M, Lee S, Xu X, Bello E, Han N, Zerbino DR, Teichmann SA, Nys J, Heuschkel R, Perrone F, Zilbauer M. Dennison TW, et al. Among authors: clatworthy mr. Gut. 2024 Aug 8;73(9):1464-1477. doi: 10.1136/gutjnl-2024-332043. Gut. 2024. PMID: 38857990 Free PMC article.
163 results