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Development of an asthma health-care burden score as a measure of severity and predictor of remission in SARP III and U-BIOPRED: results from two major longitudinal asthma cohorts.
Zein JG, Zounemat-Kerman N, Adcock IM, Hu B, Attaway A, Castro M, Dahlén SE, Denlinger LC, Erzurum SC, Fahy JV, Gaston B, Hastie AT, Israel E, Jarjour NN, Levy BD, Mauger DT, Moore W, Peters MC, Sumino K, Townsend E, Woodruff P, Ortega VE, Wenzel SE, Meyers DA, Chung KF, Bleecker ER; Unbiased Biomarkers for the Prediction of Respiratory Disease Outcomes (U-BIOPRED) Consortium and the the US National Heart, Lung, and Blood Institute Severe Asthma Research Program (SARP III). Zein JG, et al. Among authors: israel e. Lancet Respir Med. 2024 Nov 22:S2213-2600(24)00250-9. doi: 10.1016/S2213-2600(24)00250-9. Online ahead of print. Lancet Respir Med. 2024. PMID: 39586307
Alterations of the arginine metabolome in asthma.
Lara A, Khatri SB, Wang Z, Comhair SA, Xu W, Dweik RA, Bodine M, Levison BS, Hammel J, Bleecker E, Busse W, Calhoun WJ, Castro M, Chung KF, Curran-Everett D, Gaston B, Israel E, Jarjour N, Moore W, Peters SP, Teague WG, Wenzel S, Hazen SL, Erzurum SC; National Heart, Lung, and Blood Institute's Severe Asthma Research Program. Lara A, et al. Among authors: israel e. Am J Respir Crit Care Med. 2008 Oct 1;178(7):673-81. doi: 10.1164/rccm.200710-1542OC. Epub 2008 Jul 17. Am J Respir Crit Care Med. 2008. PMID: 18635886 Free PMC article.
Bronchial epithelial cell transcriptional responses to inhaled corticosteroids dictate severe asthmatic outcomes.
Ginebaugh SP, Hagner M, Ray A, Erzurum SC, Comhair SAA, Denlinger LC, Jarjour NN, Castro M, Woodruff PG, Christenson SA, Bleecker ER, Meyers DA, Hastie AT, Moore WC, Mauger DT, Israel E, Levy BD, Wenzel SE, Camiolo MJ. Ginebaugh SP, et al. Among authors: israel e. J Allergy Clin Immunol. 2023 Jun;151(6):1513-1524. doi: 10.1016/j.jaci.2023.01.028. Epub 2023 Feb 14. J Allergy Clin Immunol. 2023. PMID: 36796454 Free PMC article.
CCL5 is a potential bridge between type 1 and type 2 inflammation in asthma.
Gauthier M, Kale SL, Oriss TB, Gorry M, Ramonell RP, Dalton K, Ray P, Fahy JV, Seibold MA, Castro M, Jarjour N, Gaston B, Bleecker ER, Meyers DA, Moore W, Hastie AT, Israel E, Levy BD, Mauger D, Erzurum S, Comhair SA, Wenzel SE, Ray A. Gauthier M, et al. Among authors: israel e. J Allergy Clin Immunol. 2023 Jul;152(1):94-106.e12. doi: 10.1016/j.jaci.2023.02.028. Epub 2023 Mar 8. J Allergy Clin Immunol. 2023. PMID: 36893862 Free PMC article.
Investigations of a combination of atopic status and age of asthma onset identify asthma subphenotypes.
Li H, Castro M, Denlinger LC, Erzurum SC, Fahy JV, Gaston B, Israel E, Jarjour NN, Levy BD, Mauger DT, Moore WC, Wenzel SE, Zein J, Bleecker ER, Meyers DA, Chen Y, Li X; NHLBI Severe Asthma Research Program (SARP). Li H, et al. Among authors: israel e. J Asthma. 2023 Oct;60(10):1843-1852. doi: 10.1080/02770903.2023.2193634. Epub 2023 Apr 21. J Asthma. 2023. PMID: 36940238 Free PMC article.
Genetic analyses of chr11p15.5 region identify MUC5AC-MUC5B associated with asthma-related phenotypes.
Li X, Li H, Christenson SA, Castro M, Denlinger LC, Erzurum SC, Fahy JV, Gaston BM, Israel E, Jarjour NN, Levy BD, Mauger DT, Moore WC, Zein J, Kaminski N, Wenzel SE, Woodruff PG, Bleecker ER, Meyers DA; NHLBI Severe Asthma Research Program (SARP). Li X, et al. Among authors: israel e. J Asthma. 2023 Oct;60(10):1824-1835. doi: 10.1080/02770903.2023.2193631. Epub 2023 Apr 21. J Asthma. 2023. PMID: 36946148 Free PMC article.
Questions in Mild Asthma: An Official American Thoracic Society Research Statement.
Mohan A, Lugogo NL, Hanania NA, Reddel HK, Akuthota P, O'Byrne PM, Guilbert T, Papi A, Price D, Jenkins CR, Kraft M, Bacharier LB, Boulet LP, Yawn BP, Pleasants R, Lazarus SC, Beasley R, Gauvreau G, Israel E, Schneider-Futschik EK, Yorgancioglu A, Martinez F, Moore W, Sumino K. Mohan A, et al. Among authors: israel e. Am J Respir Crit Care Med. 2023 Jun 1;207(11):e77-e96. doi: 10.1164/rccm.202304-0642ST. Am J Respir Crit Care Med. 2023. PMID: 37260227 Free PMC article.
Association of Sputum Eosinophilia With Easily Measured Type-2 Inflammatory Biomarkers in Untreated Mild Persistent Asthma.
Covar R, Lazarus SC, Krishnan JA, Blake KV, Sorkness CA, Dyer AM, Lang JE, Lugogo NL, Mauger DT, Wechsler ME, Wenzel SE, Cardet JC, Castro M, Israel E, Phipatanakul W, King TS; National Heart, Lung, and Blood Institute AsthmaNet. Covar R, et al. Among authors: israel e. J Allergy Clin Immunol Pract. 2024 Apr;12(4):960-969.e6. doi: 10.1016/j.jaip.2023.12.010. Epub 2023 Dec 12. J Allergy Clin Immunol Pract. 2024. PMID: 38097180
Mitochondrial DNA Copy Number Variation in Asthma Risk, Severity, and Exacerbations.
Xu W, Hong YS, Hu B, Comhair SAA, Janocha AJ, Zein JG, Chen R, Meyers DA, Mauger DT, Ortega VE, Bleecker ER, Castro M, Denlinger LC, Fahy JV, Israel E, Levy BD, Jarjour NN, Moore WC, Wenzel SE, Gaston B, Liu C, Arking DE, Erzurum SC; National Heart, Lung, and Blood Institute (NHLBI) Severe Asthma Research Program (SARP) and TOPMed mtDNA Working Group in NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium. Xu W, et al. Among authors: israel e. medRxiv [Preprint]. 2023 Dec 5:2023.12.05.23299392. doi: 10.1101/2023.12.05.23299392. medRxiv. 2023. Update in: J Allergy Clin Immunol. 2024 Sep 3:S0091-6749(24)00906-0. doi: 10.1016/j.jaci.2024.08.022 PMID: 38106101 Free PMC article. Updated. Preprint.
694 results