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Page 1
Development of an asthma health-care burden score as a measure of severity and predictor of remission in SARP III and U-BIOPRED: results from two major longitudinal asthma cohorts.
Zein JG, Zounemat-Kerman N, Adcock IM, Hu B, Attaway A, Castro M, Dahlén SE, Denlinger LC, Erzurum SC, Fahy JV, Gaston B, Hastie AT, Israel E, Jarjour NN, Levy BD, Mauger DT, Moore W, Peters MC, Sumino K, Townsend E, Woodruff P, Ortega VE, Wenzel SE, Meyers DA, Chung KF, Bleecker ER; Unbiased Biomarkers for the Prediction of Respiratory Disease Outcomes (U-BIOPRED) Consortium and the the US National Heart, Lung, and Blood Institute Severe Asthma Research Program (SARP III). Zein JG, et al. Among authors: denlinger lc. Lancet Respir Med. 2024 Nov 22:S2213-2600(24)00250-9. doi: 10.1016/S2213-2600(24)00250-9. Online ahead of print. Lancet Respir Med. 2024. PMID: 39586307
Evidence for Exacerbation-Prone Asthma and Predictive Biomarkers of Exacerbation Frequency.
Peters MC, Mauger D, Ross KR, Phillips B, Gaston B, Cardet JC, Israel E, Levy BD, Phipatanakul W, Jarjour NN, Castro M, Wenzel SE, Hastie A, Moore W, Bleecker E, Fahy JV, Denlinger LC. Peters MC, et al. Among authors: denlinger lc. Am J Respir Crit Care Med. 2020 Oct 1;202(7):973-982. doi: 10.1164/rccm.201909-1813OC. Am J Respir Crit Care Med. 2020. PMID: 32479111 Free PMC article.
Mixed Sputum Granulocyte Longitudinal Impact on Lung Function in the Severe Asthma Research Program.
Hastie AT, Mauger DT, Denlinger LC, Coverstone A, Castro M, Erzurum S, Jarjour N, Levy BD, Meyers DA, Moore WC, Phillips BR, Wenzel SE, Fahy JV, Israel E, Bleecker ER. Hastie AT, et al. Among authors: denlinger lc. Am J Respir Crit Care Med. 2021 Apr 1;203(7):882-892. doi: 10.1164/rccm.202009-3713OC. Am J Respir Crit Care Med. 2021. PMID: 33545021 Free PMC article.
Low CC16 mRNA Expression Levels in Bronchial Epithelial Cells Are Associated with Asthma Severity.
Li X, Guerra S, Ledford JG, Kraft M, Li H, Hastie AT, Castro M, Denlinger LC, Erzurum SC, Fahy JV, Gaston B, Israel E, Jarjour NN, Levy BD, Mauger DT, Moore WC, Zein J, Kaminski N, Wenzel SE, Woodruff PG, Meyers DA, Bleecker ER. Li X, et al. Among authors: denlinger lc. Am J Respir Crit Care Med. 2023 Feb 15;207(4):438-451. doi: 10.1164/rccm.202206-1230OC. Am J Respir Crit Care Med. 2023. PMID: 36066606 Free PMC article.
Comparison of Asthma Phenotypes in Severe Asthma Cohorts (SARP, U-BIOPRED, ProAR and COREA) From 4 Continents.
Park SY, Fowler S, Shaw DE, Adcock IM, Sousa AR, Djukanovic R, Dahlen SE, Sterk PJ, Kermani NZ, Calhoun W, Israel E, Castro M, Mauger D, Meyers D, Bleecker E, Moore W, Busse W, Jarjour N, Denlinger L, Levy B, Choi BH, Kim SH, Jang AS, Lee T, Cho YJ, Shin YS, Cho SH, Won S, Cruz AA, Wenzel SE, Chung KF, Kim TB. Park SY, et al. Allergy Asthma Immunol Res. 2024 Jul;16(4):338-352. doi: 10.4168/aair.2024.16.4.338. Allergy Asthma Immunol Res. 2024. PMID: 39155735 Free PMC article.
Vitamin D Supplementation and the Risk of Colds in Patients with Asthma.
Denlinger LC, King TS, Cardet JC, Craig T, Holguin F, Jackson DJ, Kraft M, Peters SP, Ross K, Sumino K, Boushey HA, Jarjour NN, Wechsler ME, Wenzel SE, Castro M, Avila PC; NHLBI AsthmaNet Investigators. Denlinger LC, et al. Am J Respir Crit Care Med. 2016 Mar 15;193(6):634-41. doi: 10.1164/rccm.201506-1169OC. Am J Respir Crit Care Med. 2016. PMID: 26540136 Free PMC article. Clinical Trial.
Inflammatory and Comorbid Features of Patients with Severe Asthma and Frequent Exacerbations.
Denlinger LC, Phillips BR, Ramratnam S, Ross K, Bhakta NR, Cardet JC, Castro M, Peters SP, Phipatanakul W, Aujla S, Bacharier LB, Bleecker ER, Comhair SA, Coverstone A, DeBoer M, Erzurum SC, Fain SB, Fajt M, Fitzpatrick AM, Gaffin J, Gaston B, Hastie AT, Hawkins GA, Holguin F, Irani AM, Israel E, Levy BD, Ly N, Meyers DA, Moore WC, Myers R, Opina MT, Peters MC, Schiebler ML, Sorkness RL, Teague WG, Wenzel SE, Woodruff PG, Mauger DT, Fahy JV, Jarjour NN; National Heart, Lung, and Blood Institute’s Severe Asthma Research Program-3 Investigators. Denlinger LC, et al. Am J Respir Crit Care Med. 2017 Feb 1;195(3):302-313. doi: 10.1164/rccm.201602-0419OC. Am J Respir Crit Care Med. 2017. PMID: 27556234 Free PMC article. Clinical Trial.
ALX receptor ligands define a biochemical endotype for severe asthma.
Ricklefs I, Barkas I, Duvall MG, Cernadas M, Grossman NL, Israel E, Bleecker ER, Castro M, Erzurum SC, Fahy JV, Gaston BM, Denlinger LC, Mauger DT, Wenzel SE, Comhair SA, Coverstone AM, Fajt ML, Hastie AT, Johansson MW, Peters MC, Phillips BR, Levy BD; National Heart Lung and Blood Institute’s Severe Asthma Research Program-3 Investigators. Ricklefs I, et al. Among authors: denlinger lc. JCI Insight. 2017 Jul 20;2(14):e93534. doi: 10.1172/jci.insight.93534. eCollection 2017 Jul 20. JCI Insight. 2017. PMID: 28724795 Free PMC article.
Baseline Features of the Severe Asthma Research Program (SARP III) Cohort: Differences with Age.
Teague WG, Phillips BR, Fahy JV, Wenzel SE, Fitzpatrick AM, Moore WC, Hastie AT, Bleecker ER, Meyers DA, Peters SP, Castro M, Coverstone AM, Bacharier LB, Ly NP, Peters MC, Denlinger LC, Ramratnam S, Sorkness RL, Gaston BM, Erzurum SC, Comhair SAA, Myers RE, Zein J, DeBoer MD, Irani AM, Israel E, Levy B, Cardet JC, Phipatanakul W, Gaffin JM, Holguin F, Fajt ML, Aujla SJ, Mauger DT, Jarjour NN. Teague WG, et al. Among authors: denlinger lc. J Allergy Clin Immunol Pract. 2018 Mar-Apr;6(2):545-554.e4. doi: 10.1016/j.jaip.2017.05.032. Epub 2017 Aug 31. J Allergy Clin Immunol Pract. 2018. PMID: 28866107 Free PMC article.
Internet-Based Monitoring in the Severe Asthma Research Program Identifies a Subgroup of Patients With Labile Asthma Control.
Wong-McGrath K, Denlinger LC, Bleecker ER, Castro M, Gaston B, Israel E, Jarjour NN, Mauger DT, Peters S, Phillips BR, Wenzel SE, Fahy JV, Peters MC; National Heart Lung and Blood Institute’s Severe Asthma Research Program-3 Investigators. Wong-McGrath K, et al. Among authors: denlinger lc. Chest. 2018 Feb;153(2):378-386. doi: 10.1016/j.chest.2017.10.017. Epub 2017 Oct 26. Chest. 2018. PMID: 29080709 Free PMC article.
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