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The strand exchange domain of tumor suppressor PALB2 is intrinsically disordered and promotes oligomerization-dependent DNA compaction.
Kyriukha Y, Watkins MB, Redington JM, Dastvan R, Uversky VN, Hopkins JB, Pozzi N, Korolev S. Kyriukha Y, et al. bioRxiv [Preprint]. 2024 May 29:2023.06.01.543259. doi: 10.1101/2023.06.01.543259. bioRxiv. 2024. Update in: iScience. 2024 Oct 28;27(12):111259. doi: 10.1016/j.isci.2024.111259 PMID: 37333393 Free PMC article. Updated. Preprint.
α-Synuclein Dimers as Potent Inhibitors of Fibrillization.
Kyriukha YA, Afitska K, Kurochka AS, Sachan S, Galkin M, Yushchenko DA, Shvadchak VV. Kyriukha YA, et al. J Med Chem. 2019 Nov 27;62(22):10342-10351. doi: 10.1021/acs.jmedchem.9b01400. Epub 2019 Nov 4. J Med Chem. 2019. PMID: 31625739