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Page 1
Thermal sensitivity and flexibility of the Cε3 domains in immunoglobulin E.
Doré KA, Davies AM, Drinkwater N, Beavil AJ, McDonnell JM, Sutton BJ. Doré KA, et al. Among authors: mcdonnell jm. Biochim Biophys Acta Proteins Proteom. 2017 Nov;1865(11 Pt A):1336-1347. doi: 10.1016/j.bbapap.2017.08.005. Epub 2017 Aug 24. Biochim Biophys Acta Proteins Proteom. 2017. PMID: 28844738 Free PMC article.
Crystal structure of IgE bound to its B-cell receptor CD23 reveals a mechanism of reciprocal allosteric inhibition with high affinity receptor FcεRI.
Dhaliwal B, Yuan D, Pang MO, Henry AJ, Cain K, Oxbrow A, Fabiane SM, Beavil AJ, McDonnell JM, Gould HJ, Sutton BJ. Dhaliwal B, et al. Among authors: mcdonnell jm. Proc Natl Acad Sci U S A. 2012 Jul 31;109(31):12686-91. doi: 10.1073/pnas.1207278109. Epub 2012 Jul 16. Proc Natl Acad Sci U S A. 2012. PMID: 22802656 Free PMC article.
Conformational plasticity at the IgE-binding site of the B-cell receptor CD23.
Dhaliwal B, Pang MO, Yuan D, Yahya N, Fabiane SM, McDonnell JM, Gould HJ, Beavil AJ, Sutton BJ. Dhaliwal B, et al. Among authors: mcdonnell jm. Mol Immunol. 2013 Dec;56(4):693-7. doi: 10.1016/j.molimm.2013.07.005. Epub 2013 Aug 7. Mol Immunol. 2013. PMID: 23933509 Free PMC article.
IgE binds asymmetrically to its B cell receptor CD23.
Dhaliwal B, Pang MO, Keeble AH, James LK, Gould HJ, McDonnell JM, Sutton BJ, Beavil AJ. Dhaliwal B, et al. Among authors: mcdonnell jm. Sci Rep. 2017 Mar 31;7:45533. doi: 10.1038/srep45533. Sci Rep. 2017. PMID: 28361904 Free PMC article.
Allosteric mechanism of action of the therapeutic anti-IgE antibody omalizumab.
Davies AM, Allan EG, Keeble AH, Delgado J, Cossins BP, Mitropoulou AN, Pang MOY, Ceska T, Beavil AJ, Craggs G, Westwood M, Henry AJ, McDonnell JM, Sutton BJ. Davies AM, et al. Among authors: mcdonnell jm. J Biol Chem. 2017 Jun 16;292(24):9975-9987. doi: 10.1074/jbc.M117.776476. Epub 2017 Apr 24. J Biol Chem. 2017. PMID: 28438838 Free PMC article.
146 results