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Multi-omic and single-cell profiling of chromothriptic medulloblastoma reveals genomic and transcriptomic consequences of genome instability.
Smirnov P, Przybilla MJ, Simovic-Lorenz M, Parra RG, Susak H, Ratnaparkhe M, Wong JK, Körber V, Mallm JP, Philippos G, Sill M, Kolb T, Kumar R, Casiraghi N, Okonechnikov K, Ghasemi DR, Maaß KK, Pajtler KW, Jauch A, Korshunov A, Höfer T, Zapatka M, Pfister SM, Huber W, Stegle O, Ernst A. Smirnov P, et al. Among authors: hofer t. Nat Commun. 2024 Nov 23;15(1):10183. doi: 10.1038/s41467-024-54547-w. Nat Commun. 2024. PMID: 39580568 Free PMC article.
Carbon ion radiotherapy eradicates medulloblastomas with chromothripsis in an orthotopic Li-Fraumeni patient-derived mouse model.
Simovic M, Bolkestein M, Moustafa M, Wong JKL, Körber V, Benedetto S, Khalid U, Schreiber HS, Jugold M, Korshunov A, Hübschmann D, Mack N, Brons S, Wei PC, Breckwoldt MO, Heiland S, Bendszus M, Debus J, Höfer T, Zapatka M, Kool M, Pfister SM, Abdollahi A, Ernst A. Simovic M, et al. Among authors: hofer t. Neuro Oncol. 2021 Dec 1;23(12):2028-2041. doi: 10.1093/neuonc/noab127. Neuro Oncol. 2021. PMID: 34049392 Free PMC article.
Chromothripsis in Human Breast Cancer.
Bolkestein M, Wong JKL, Thewes V, Körber V, Hlevnjak M, Elgaafary S, Schulze M, Kommoss FKF, Sinn HP, Anzeneder T, Hirsch S, Devens F, Schröter P, Höfer T, Schneeweiss A, Lichter P, Zapatka M, Ernst A. Bolkestein M, et al. Among authors: hofer t. Cancer Res. 2020 Nov 15;80(22):4918-4931. doi: 10.1158/0008-5472.CAN-20-1920. Epub 2020 Sep 24. Cancer Res. 2020. PMID: 32973084
Polylox barcoding reveals haematopoietic stem cell fates realized in vivo.
Pei W, Feyerabend TB, Rössler J, Wang X, Postrach D, Busch K, Rode I, Klapproth K, Dietlein N, Quedenau C, Chen W, Sauer S, Wolf S, Höfer T, Rodewald HR. Pei W, et al. Among authors: hofer t. Nature. 2017 Aug 24;548(7668):456-460. doi: 10.1038/nature23653. Epub 2017 Aug 16. Nature. 2017. PMID: 28813413 Free PMC article.
Specificity, propagation, and memory of pericentric heterochromatin.
Müller-Ott K, Erdel F, Matveeva A, Mallm JP, Rademacher A, Hahn M, Bauer C, Zhang Q, Kaltofen S, Schotta G, Höfer T, Rippe K. Müller-Ott K, et al. Among authors: hofer t. Mol Syst Biol. 2014 Aug 18;10(8):746. doi: 10.15252/msb.20145377. Mol Syst Biol. 2014. PMID: 25134515 Free PMC article.
669 results