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Mutation burden and anti-PD-1 outcomes are not universally associated with immune cell infiltration or lymphoid activation.
Hsiehchen D, Elliott A, Xiu J, Seeber A, El-Deiry W, Antonarakis ES, Graff SL, Hall MJ, Borghaei H, Hoon DSB, Liu SV, Ma PC, McKay RR, Wise-Draper T, Marshall J, Sledge GW, Spetzler D, Zhu H. Hsiehchen D, et al. Among authors: graff sl. Cancer Cell. 2024 Dec 9;42(12):1985-1987. doi: 10.1016/j.ccell.2024.10.017. Epub 2024 Nov 21. Cancer Cell. 2024. PMID: 39577419
Tissue-specific thresholds of mutation burden associated with anti-PD-1/L1 therapy benefit and prognosis in microsatellite-stable cancers.
Muquith M, Espinoza M, Elliott A, Xiu J, Seeber A, El-Deiry W, Antonarakis ES, Graff SL, Hall MJ, Borghaei H, Hoon DSB, Liu SV, Ma PC, McKay RR, Wise-Draper T, Marshall J, Sledge GW, Spetzler D, Zhu H, Hsiehchen D. Muquith M, et al. Among authors: graff sl. Nat Cancer. 2024 Jul;5(7):1121-1129. doi: 10.1038/s43018-024-00752-x. Epub 2024 Mar 25. Nat Cancer. 2024. PMID: 38528112
Genomic and transcriptomic landscape of HER2-low breast cancer.
Bansal R, Adeyelu T, Elliott A, Walker P, Bustos MA, Rodriguez E, Accordino MK, Meisel J, Gatti-Mays ME, Hsu E, Lathrop K, Kaklamani V, Oberley M, Sledge G, Sammons SL, Graff SL. Bansal R, et al. Among authors: graff sl. Breast Cancer Res Treat. 2025 Jan;209(2):323-330. doi: 10.1007/s10549-024-07495-4. Epub 2024 Sep 20. Breast Cancer Res Treat. 2025. PMID: 39302579
TRAIL agonists rescue mice from radiation-induced lung, skin or esophageal injury.
Strandberg J, Louie A, Lee S, Hahn M, Srinivasan P, George A, De La Cruz A, Zhang L, Hernandez Borrero L, Huntington KE, De La Cruz P, Seyhan AA, Koffer PP, Wazer DE, DiPetrillo TA, Graff SL, Azzoli CG, Rounds SI, Klein-Szanto AJ, Tavora F, Yakirevich E, Abbas AE, Zhou L, El-Deiry WS. Strandberg J, et al. Among authors: graff sl. J Clin Invest. 2025 Jan 14:e173649. doi: 10.1172/JCI173649. Online ahead of print. J Clin Invest. 2025. PMID: 39808500 Free article.
54 results