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Page 1
Clinicogenomic landscape of pancreatic adenocarcinoma identifies KRAS mutant dosage as prognostic of overall survival.
Varghese AM, Perry MA, Chou JF, Nandakumar S, Muldoon D, Erakky A, Zucker A, Fong C, Mehine M, Nguyen B, Basturk O, Balogun F, Kelsen DP, Brannon AR, Mandelker D, Vakiani E, Park W, Yu KH, Stadler ZK, Schattner MA, Jarnagin WR, Wei AC, Chakravarty D, Capanu M, Schultz N, Berger MF, Iacobuzio-Donahue CA, Bandlamudi C, O'Reilly EM. Varghese AM, et al. Among authors: iacobuzio donahue ca. Nat Med. 2025 Jan 3. doi: 10.1038/s41591-024-03362-3. Online ahead of print. Nat Med. 2025. PMID: 39753968
Islands of genomic stability in the face of genetically unstable metastatic cancer.
Bowland K, Lai J, Skaist A, Zhang Y, Teh SSK, Roberts NJ, Thompson E, Wheelan SJ, Hruban RH, Karchin R, Bailey MH, Iacobuzio-Donahue CA, Eshleman JR. Bowland K, et al. Among authors: iacobuzio donahue ca. PLoS One. 2024 Dec 19;19(12):e0298490. doi: 10.1371/journal.pone.0298490. eCollection 2024. PLoS One. 2024. PMID: 39700179 Free PMC article.
Cancer cells restrict immunogenicity of retrotransposon expression via distinct mechanisms.
Sun S, You E, Hong J, Hoyos D, Del Priore I, Tsanov KM, Mattagajasingh O, Di Gioacchino A, Marhon SA, Chacon-Barahona J, Li H, Jiang H, Hozeifi S, Rosas-Bringas O, Xu KH, Song Y, Lang ER, Rojas AS, Nieman LT, Patel BK, Murali R, Chanda P, Karacay A, Vabret N, De Carvalho DD, Zenklusen D, LaCava J, Lowe SW, Ting DT, Iacobuzio-Donahue CA, Solovyov A, Greenbaum BD. Sun S, et al. Among authors: iacobuzio donahue ca. Immunity. 2024 Dec 10;57(12):2879-2894.e11. doi: 10.1016/j.immuni.2024.10.015. Epub 2024 Nov 21. Immunity. 2024. PMID: 39577413 Free article.
The Evolutionary Forest of Pancreatic Cancer.
Mullen KM, Hong J, Attiyeh MA, Hayashi A, Sakamoto H, Kohutek ZA, McIntyre CA, Zhang H, Makohon-Moore AP, Zucker A, Wood LD, Myers MA, Arnold BJ, Zaccaria S, Chou JF, Capanu M, Socci ND, Raphael BJ, Iacobuzio-Donahue CA. Mullen KM, et al. Among authors: iacobuzio donahue ca. Cancer Discov. 2024 Oct 8. doi: 10.1158/2159-8290.CD-23-1541. Online ahead of print. Cancer Discov. 2024. PMID: 39378050
Mechanism of neurodegeneration mediated by clonal inflammatory microglia.
Vicario R, Fragkogianni S, Pokrovskii M, Mayer C, Lopez-Rodrigo E, Hu Y, Ogishi M, Alberdi A, Baako A, Ay O, Plu I, Sazdovitch V, Heritier S, Cohen-Aubart F, Shor N, Miyara M, Nguyen-Khac F, Viale A, Idbaih A, Amoura Z, Rosenblum MK, Zhang H, Karnoub ER, Sashittal P, Jakatdar A, Iacobuzio-Donahue CA, Abdel-Wahab O, Tabar V, Socci ND, Elemento O, Diamond EL, Boisson B, Casanova JL, Seilhean D, Haroche J, Donadieu J, Geissmann F. Vicario R, et al. Among authors: iacobuzio donahue ca. bioRxiv [Preprint]. 2024 Jul 31:2024.07.30.605867. doi: 10.1101/2024.07.30.605867. bioRxiv. 2024. PMID: 39131366 Free PMC article. Preprint.
Combination immunohistochemistry for CK5/6, p63, GATA6, and HNF4a predicts clinical outcome in treatment-naïve pancreatic ductal adenocarcinoma.
Shibayama T, Hayashi A, Toki M, Kitahama K, Ho YJ, Kato K, Yamada T, Kawamoto S, Kambayashi K, Ochiai K, Gondo K, Okano N, Melchor JP, Iacobuzio-Donahue CA, Sakamoto Y, Hisamatsu T, Shibahara J. Shibayama T, et al. Among authors: iacobuzio donahue ca. Sci Rep. 2024 Jul 6;14(1):15598. doi: 10.1038/s41598-024-65900-w. Sci Rep. 2024. PMID: 38971768 Free PMC article.
Multi-parametric atlas of the pre-metastatic liver for prediction of metastatic outcome in early-stage pancreatic cancer.
Bojmar L, Zambirinis CP, Hernandez JM, Chakraborty J, Shaashua L, Kim J, Johnson KE, Hanna S, Askan G, Burman J, Ravichandran H, Zheng J, Jolissaint JS, Srouji R, Song Y, Choubey A, Kim HS, Cioffi M, van Beek E, Sigel C, Jessurun J, Velasco Riestra P, Blomstrand H, Jönsson C, Jönsson A, Lauritzen P, Buehring W, Ararso Y, Hernandez D, Vinagolu-Baur JP, Friedman M, Glidden C, Firmenich L, Lieberman G, Mejia DL, Nasar N, Mutvei AP, Paul DM, Bram Y, Costa-Silva B, Basturk O, Boudreau N, Zhang H, Matei IR, Hoshino A, Kelsen D, Sagi I, Scherz A, Scherz-Shouval R, Yarden Y, Oren M, Egeblad M, Lewis JS, Keshari K, Grandgenett PM, Hollingsworth MA, Rajasekhar VK, Healey JH, Björnsson B, Simeone DM, Tuveson DA, Iacobuzio-Donahue CA, Bromberg J, Vincent CT, O'Reilly EM, DeMatteo RP, Balachandran VP, D'Angelica MI, Kingham TP, Allen PJ, Simpson AL, Elemento O, Sandström P, Schwartz RE, Jarnagin WR, Lyden D. Bojmar L, et al. Among authors: iacobuzio donahue ca. Nat Med. 2024 Aug;30(8):2170-2180. doi: 10.1038/s41591-024-03075-7. Epub 2024 Jun 28. Nat Med. 2024. PMID: 38942992 Free PMC article.
Metastatic site influences driver gene function in pancreatic cancer.
Tsanov KM, Barriga FM, Ho YJ, Alonso-Curbelo D, Livshits G, Koche RP, Baslan T, Simon J, Tian S, Wuest AN, Luan W, Wilkinson JE, Masilionis I, Dimitrova N, Iacobuzio-Donahue CA, Chaligné R, Pe'er D, Massagué J, Lowe SW. Tsanov KM, et al. Among authors: iacobuzio donahue ca. bioRxiv [Preprint]. 2024 Mar 18:2024.03.17.585402. doi: 10.1101/2024.03.17.585402. bioRxiv. 2024. PMID: 38562717 Free PMC article. Preprint.
282 results