Volkman BF - Search Results

1

Discovery of Selective Cyclic d-Sulfopeptide Ligands of the Chemokine CCL22 via Mirror-Image mRNA Display with Genetic Reprogramming.

Zhang BB, Harrison K, Zhong Y, Maxwell JWC, Ford DJ, Calvey LP, So SS, Peterson FC, Volkman BF, Stone MJ, Bhusal RP, Kulkarni SS, Payne RJ. Zhang BB, et al. Among authors: volkman bf. J Am Chem Soc. 2024 Dec 18;146(50):34253-34259. doi: 10.1021/jacs.4c12057. Epub 2024 Dec 4. J Am Chem Soc. 2024. PMID: 39629944

2

Constitutive activity of an atypical chemokine receptor revealed by inverse agonistic nanobodies.

Perez Almeria CV, Otun O, Schlimgen R, Lamme TD, Crudden C, Youssef N, Musli L, Jenjak S, Bobkov V, Drube J, Hoffmann C, Volkman BF, Granier S, Bechara C, Siderius M, Heukers R, Schafer CT, Smit MJ. Perez Almeria CV, et al. Among authors: volkman bf. bioRxiv [Preprint]. 2024 Nov 4:2024.11.04.621790. doi: 10.1101/2024.11.04.621790. bioRxiv. 2024. PMID: 39574661 Free PMC article. Preprint.

3

Molecular basis for chemokine recognition and activation of XCR1.

Zhang X, Schlimgen RR, Singh S, Tomani MP, Volkman BF, Zhang C. Zhang X, et al. Among authors: volkman bf. Proc Natl Acad Sci U S A. 2024 Nov 26;121(48):e2405732121. doi: 10.1073/pnas.2405732121. Epub 2024 Nov 20. Proc Natl Acad Sci U S A. 2024. PMID: 39565315

4

Chemokine Receptor N-Terminus Charge Dictates Reliance on Post-Translational Modifications for Effective Ligand Capture and Following Boosting by Defense Peptides.

Xu T, Schou AS, Lackman JJ, Barrio-Calvo M, Verhallen L, Goth CK, Jensen BAH, Veldkamp CT, Volkman BF, Peterson FC, Hjortø GM. Xu T, et al. Among authors: volkman bf. Int J Mol Sci. 2024 Oct 9;25(19):10854. doi: 10.3390/ijms251910854. Int J Mol Sci. 2024. PMID: 39409188 Free PMC article.

5

Chemokines Kill Bacteria by Binding Anionic Phospholipids without Triggering Antimicrobial Resistance.

Pontejo SM, Martinez S, Zhao A, Barnes K, de Anda J, Alimohamadi H, Lee EY, Dishman AF, Volkman BF, Wong GCL, Garboczi DN, Ballesteros A, Murphy PM. Pontejo SM, et al. Among authors: volkman bf. bioRxiv [Preprint]. 2024 Jul 25:2024.07.25.604863. doi: 10.1101/2024.07.25.604863. bioRxiv. 2024. PMID: 39091850 Free PMC article. Preprint.

6

Structural basis for selectivity and antagonism in extracellular GPCR-nanobodies.

Schlimgen RR, Peterson FC, Heukers R, Smit MJ, McCorvy JD, Volkman BF. Schlimgen RR, et al. Among authors: volkman bf. Nat Commun. 2024 May 30;15(1):4611. doi: 10.1038/s41467-024-49000-x. Nat Commun. 2024. PMID: 38816420 Free PMC article.

7

Deep computational phenotyping of genomic variants impacting the SET domain of KMT2C reveal molecular mechanisms for their dysfunction.

Jorge SD, Chi YI, Mazaba JL, Haque N, Wagenknecht J, Smith BC, Volkman BF, Mathison AJ, Lomberk G, Zimmermann MT, Urrutia R. Jorge SD, et al. Among authors: volkman bf. Front Genet. 2023 Nov 28;14:1291307. doi: 10.3389/fgene.2023.1291307. eCollection 2023. Front Genet. 2023. PMID: 38090150 Free PMC article.

8

A multi-layered computational structural genomics approach enhances domain-specific interpretation of Kleefstra syndrome variants in EHMT1.

Chi YI, Jorge SD, Jensen DR, Smith BC, Volkman BF, Mathison AJ, Lomberk G, Zimmermann MT, Urrutia R. Chi YI, et al. Among authors: volkman bf. Comput Struct Biotechnol J. 2023 Oct 13;21:5249-5258. doi: 10.1016/j.csbj.2023.10.022. eCollection 2023. Comput Struct Biotechnol J. 2023. PMID: 37954151 Free PMC article.

9

An orthogonalized PYR1-based CID module with reprogrammable ligand-binding specificity.

Park SY, Qiu J, Wei S, Peterson FC, Beltrán J, Medina-Cucurella AV, Vaidya AS, Xing Z, Volkman BF, Nusinow DA, Whitehead TA, Wheeldon I, Cutler SR. Park SY, et al. Among authors: volkman bf. Nat Chem Biol. 2024 Jan;20(1):103-110. doi: 10.1038/s41589-023-01447-7. Epub 2023 Oct 23. Nat Chem Biol. 2024. PMID: 37872402 Free PMC article.

10

Fragment-based screening by protein-detected NMR spectroscopy.

Kerber PJ, Nuñez R, Jensen DR, Zhou AL, Peterson FC, Hill RB, Volkman BF, Smith BC. Kerber PJ, et al. Among authors: volkman bf. Methods Enzymol. 2023;690:285-310. doi: 10.1016/bs.mie.2023.06.018. Epub 2023 Jul 29. Methods Enzymol. 2023. PMID: 37858532 Free PMC article.

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