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Page 1
Deeper response predicts better outcomes in high-risk-smoldering-myeloma: results of the I-PRISM phase II clinical trial.
Nadeem O, Aranha MP, Redd R, Timonian M, Magidson S, Lightbody ED, Alberge JB, Bertamini L, Dutta AK, El-Khoury H, Bustoros M, Laubach JP, Bianchi G, O'Donnell E, Wu T, Tsuji J, Anderson KC, Getz G, Trippa L, Richardson PG, Sklavenitis-Pistofidis R, Ghobrial IM. Nadeem O, et al. Among authors: alberge jb. Nat Commun. 2025 Jan 3;16(1):358. doi: 10.1038/s41467-024-55308-5. Nat Commun. 2025. PMID: 39753553 Free PMC article. Clinical Trial.
Serum free light chains in a racially diverse population including African Americans and populations from South Africa.
Bertamini L, Alberge JB, Lee DJ, El-Khoury H, Kim S, Fleming G, Murphy CSM, Colchie J, Davis MI, Perry J, Lightbody ED, Allam S, Goqwana LN, Philip V, Smyth NA NA, Sakrikar D, Perkins MC, Harding S, Troske D, Getz G, Karlson EW, Munshi NC, Anderson KC, Trippa L, Marinac CR, Chen WC, Joffe M, Ghobrial IM. Bertamini L, et al. Among authors: alberge jb. Blood. 2024 Nov 21:blood.2024026078. doi: 10.1182/blood.2024026078. Online ahead of print. Blood. 2024. PMID: 39571144
Selective Enhancer Gain-of-Function Deregulates MYC Expression in Multiple Myeloma.
Rahmat M, Clement K, Alberge JB, Sklavenitis-Pistofidis R, Kodgule R, Fulco CP, Heilpern-Mallory D, Nilsson K, Dorfman D, Engreitz JM, Getz G, Pinello L, Ryan RJH, Ghobrial IM. Rahmat M, et al. Among authors: alberge jb. Cancer Res. 2024 Dec 16;84(24):4173-4183. doi: 10.1158/0008-5472.CAN-24-1440. Cancer Res. 2024. PMID: 39312195
Inhibition of MICA and MICB shedding enhances memory-like NK-cell-mediated cytotoxicity against multiple myeloma.
Tahri S, Piccinelli S, Su NK, Lampe L, Dong H, Vergara Cadavid J, Boiarsky R, Papazian N, Lightbody ED, Cao A, Alberge JB, Ferrari de Andrade L, Rahmat M, Shen Y, Blanco Fernández L, Zabaleta A, Günther A, Getz G, Sonneveld P, Cupedo T, Wucherpfennig KW, Ghobrial IM, Romee R. Tahri S, et al. Among authors: alberge jb. Blood Adv. 2024 Oct 22;8(20):5365-5370. doi: 10.1182/bloodadvances.2023010869. Blood Adv. 2024. PMID: 39106432 Free PMC article. No abstract available.
A systematic review and meta-analysis of nonrelapse mortality after CAR T cell therapy.
Cordas Dos Santos DM, Tix T, Shouval R, Gafter-Gvili A, Alberge JB, Cliff ERS, Theurich S, von Bergwelt-Baildon M, Ghobrial IM, Subklewe M, Perales MA, Rejeski K. Cordas Dos Santos DM, et al. Among authors: alberge jb. Nat Med. 2024 Sep;30(9):2667-2678. doi: 10.1038/s41591-024-03084-6. Epub 2024 Jul 8. Nat Med. 2024. PMID: 38977912 Free PMC article.
Long-Term Follow-Up Defines the Population That Benefits from Early Interception in a High-Risk Smoldering Multiple Myeloma Clinical Trial Using the Combination of Ixazomib, Lenalidomide, and Dexamethasone.
Nadeem O, Aranha MP, Redd R, Timonian M, Magidson S, Lightbody ED, Alberge JB, Bertamini L, Dutta AK, El-Khoury H, Bustoros M, Laubach JP, Bianchi G, O'Donnell E, Wu T, Tsuji J, Anderson K, Getz G, Trippa L, Richardson PG, Sklavenitis-Pistofidis R, Ghobrial IM. Nadeem O, et al. Among authors: alberge jb. medRxiv [Preprint]. 2024 Apr 19:2024.04.19.24306082. doi: 10.1101/2024.04.19.24306082. medRxiv. 2024. PMID: 38699307 Free PMC article. Preprint.
Mass spectrometry-detected MGUS is associated with obesity and other novel modifiable risk factors in a high-risk population.
Lee DJ, El-Khoury H, Tramontano AC, Alberge JB, Perry J, Davis MI, Horowitz E, Redd R, Sakrikar D, Barnidge D, Perkins MC, Harding S, Mucci L, Rebbeck TR, Ghobrial IM, Marinac CR. Lee DJ, et al. Among authors: alberge jb. Blood Adv. 2024 Apr 9;8(7):1737-1746. doi: 10.1182/bloodadvances.2023010843. Blood Adv. 2024. PMID: 38212245 Free PMC article. Clinical Trial.
A p53 score derived from TP53 CRISPR/Cas9 HMCLs predicts survival and reveals a major role of BAX in the response to BH3 mimetics.
Durand R, Descamps G, Bellanger C, Dousset C, Maïga S, Alberge JB, Derrien J, Cruard J, Minvielle S, Lilli NL, Godon C, Le Bris Y, Tessoulin B, Amiot M, Gomez-Bougie P, Touzeau C, Moreau P, Chiron D, Moreau-Aubry A, Pellat-Deceunynck C. Durand R, et al. Among authors: alberge jb. Blood. 2024 Mar 28;143(13):1242-1258. doi: 10.1182/blood.2023021581. Blood. 2024. PMID: 38096363
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