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Page 1
Lewy pathology formation in patient-derived GBA1 Parkinson's disease midbrain organoids.
Frattini E, Faustini G, Lopez G, Carsana EV, Tosi M, Trezzi I, Magni M, Soldà G, Straniero L, Facchi D, Samarani M, Martá-Ariza M, De Luca CMG, Vezzoli E, Pittaro A, Stepanyan A, Silipigni R, Rosety I, Schwamborn JC, Sardi SP, Moda F, Corti S, Comi GP, Blandini F, Tritsch NX, Bortolozzi M, Ferrero S, Cribiù FM, Wisniewski T, Asselta R, Aureli M, Bellucci A, Di Fonzo A. Frattini E, et al. Among authors: samarani m. Brain. 2024 Nov 21:awae365. doi: 10.1093/brain/awae365. Online ahead of print. Brain. 2024. PMID: 39570889
β-Glucocerebrosidase Deficiency Activates an Aberrant Lysosome-Plasma Membrane Axis Responsible for the Onset of Neurodegeneration.
Lunghi G, Carsana EV, Loberto N, Cioccarelli L, Prioni S, Mauri L, Bassi R, Duga S, Straniero L, Asselta R, Soldà G, Di Fonzo A, Frattini E, Magni M, Liessi N, Armirotti A, Ferrari E, Samarani M, Aureli M. Lunghi G, et al. Among authors: samarani m. Cells. 2022 Jul 29;11(15):2343. doi: 10.3390/cells11152343. Cells. 2022. PMID: 35954187 Free PMC article.
Massive Accumulation of Sphingomyelin Affects the Lysosomal and Mitochondria Compartments and Promotes Apoptosis in Niemann-Pick Disease Type A.
Carsana EV, Lunghi G, Prioni S, Mauri L, Loberto N, Prinetti A, Zucca FA, Bassi R, Sonnino S, Chiricozzi E, Duga S, Straniero L, Asselta R, Soldà G, Samarani M, Aureli M. Carsana EV, et al. Among authors: samarani m. J Mol Neurosci. 2022 Jul;72(7):1482-1499. doi: 10.1007/s12031-022-02036-4. Epub 2022 Jun 21. J Mol Neurosci. 2022. PMID: 35727525 Free PMC article.
Transcriptomic characterization of tissues from patients and subsequent pathway analyses reveal biological pathways that are implicated in spastic ataxia.
Kakouri AC, Votsi C, Oulas A, Nicolaou P, Aureli M, Lunghi G, Samarani M, Compagnoni GM, Salani S, Di Fonzo A, Christophides T, Tanteles GA, Zamba-Papanicolaou E, Pantzaris M, Spyrou GM, Christodoulou K. Kakouri AC, et al. Among authors: samarani m. Cell Biosci. 2022 Mar 11;12(1):29. doi: 10.1186/s13578-022-00754-1. Cell Biosci. 2022. PMID: 35277195 Free PMC article.
α-Synuclein fibrils subvert lysosome structure and function for the propagation of protein misfolding between cells through tunneling nanotubes.
Dilsizoglu Senol A, Samarani M, Syan S, Guardia CM, Nonaka T, Liv N, Latour-Lambert P, Hasegawa M, Klumperman J, Bonifacino JS, Zurzolo C. Dilsizoglu Senol A, et al. Among authors: samarani m. PLoS Biol. 2021 Jul 20;19(7):e3001287. doi: 10.1371/journal.pbio.3001287. eCollection 2021 Jul. PLoS Biol. 2021. PMID: 34283825 Free PMC article.
Mitochondrial Dysregulation and Impaired Autophagy in iPSC-Derived Dopaminergic Neurons of Multiple System Atrophy.
Monzio Compagnoni G, Kleiner G, Samarani M, Aureli M, Faustini G, Bellucci A, Ronchi D, Bordoni A, Garbellini M, Salani S, Fortunato F, Frattini E, Abati E, Bergamini C, Fato R, Tabano S, Miozzo M, Serratto G, Passafaro M, Deleidi M, Silipigni R, Nizzardo M, Bresolin N, Comi GP, Corti S, Quinzii CM, Di Fonzo A. Monzio Compagnoni G, et al. Among authors: samarani m. Stem Cell Reports. 2018 Nov 13;11(5):1185-1198. doi: 10.1016/j.stemcr.2018.09.007. Epub 2018 Oct 18. Stem Cell Reports. 2018. PMID: 30344007 Free PMC article.
22 results