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Sepsis pathogenesis and outcome are shaped by the balance between the transcriptional states of systemic inflammation and antimicrobial response.
Brandes-Leibovitz R, Riza A, Yankovitz G, Pirvu A, Dorobantu S, Dragos A, Streata I, Ricaño-Ponce I, de Nooijer A, Dumitrescu F, Antonakos N, Antoniadou E, Dimopoulos G, Koutsodimitropoulos I, Kontopoulou T, Markopoulou D, Aimoniotou E, Komnos A, Dalekos GN, Ioana M, Giamarellos-Bourboulis EJ, Gat-Viks I, Netea MG. Brandes-Leibovitz R, et al. Among authors: de nooijer a. Cell Rep Med. 2024 Nov 19;5(11):101829. doi: 10.1016/j.xcrm.2024.101829. Cell Rep Med. 2024. PMID: 39566468 Free PMC article.
Regulation of plasma soluble receptors of TNF and IL-1 in patients with COVID-19 differs from that observed in sepsis.
Aksu MD, van der Ent T, Zhang Z, Riza AL, de Nooijer AH, Ricaño-Ponce I, Janssen N, Engel JJ, Streata I, Dijkstra H, Lemmers H, Grondman I, Koeken VACM, Antoniadou E, Antonakos N, van de Veerdonk FL, Li Y, Giamarellos-Bourboulis EJ, Netea MG, Ziogas A. Aksu MD, et al. Among authors: de nooijer ah. J Infect. 2024 Dec;89(6):106300. doi: 10.1016/j.jinf.2024.106300. Epub 2024 Sep 30. J Infect. 2024. PMID: 39357572 Free PMC article.
ImmunoSep (Personalised Immunotherapy in Sepsis) international double-blind, double-dummy, placebo-controlled randomised clinical trial: study protocol.
Kotsaki A, Pickkers P, Bauer M, Calandra T, Lupse M, Wiersinga WJ, Meylan S, Bloos F, van der Poll T, Slim MA, van Mourik N, Müller MCA, van Vught L, Vlaar APJ, de Nooijer A, Bakkerus L, Weis S, Antonakos N, Netea MG, Giamarellos-Bourboulis EJ. Kotsaki A, et al. Among authors: de nooijer a. BMJ Open. 2022 Dec 20;12(12):e067251. doi: 10.1136/bmjopen-2022-067251. BMJ Open. 2022. PMID: 36600424 Free PMC article.
Adipocytokine plasma concentrations reflect influence of inflammation but not body mass index (BMI) on clinical outcomes of COVID-19 patients: A prospective observational study from the Netherlands.
de Nooijer AH, Kooistra EJ, Grondman I, Janssen NAF, Joosten LAB, van de Veerdonk FL, Kox M, Pickkers P, Netea MG; RCI-COVID-19 study group. de Nooijer AH, et al. Clin Obes. 2023 Apr;13(2):e12568. doi: 10.1111/cob.12568. Epub 2022 Nov 25. Clin Obes. 2023. PMID: 36426776
Targeted proteomics identifies circulating biomarkers associated with active COVID-19 and post-COVID-19.
Zoodsma M, de Nooijer AH, Grondman I, Gupta MK, Bonifacius A, Koeken VACM, Kooistra E, Kilic G, Bulut O, Gödecke N, Janssen N, Kox M, Domínguez-Andrés J, van Gammeren AJ, Ermens AAM, van der Ven AJAM, Pickkers P, Blasczyk R, Behrens GMN, van de Veerdonk FL, Joosten LAB, Xu CJ, Eiz-Vesper B, Netea MG, Li Y. Zoodsma M, et al. Among authors: de nooijer ah. Front Immunol. 2022 Nov 3;13:1027122. doi: 10.3389/fimmu.2022.1027122. eCollection 2022. Front Immunol. 2022. PMID: 36405747 Free PMC article.
Exploratory analysis of interleukin-38 in hospitalized COVID-19 patients.
de Graaf DM, Teufel LU, de Nooijer AH, van Gammeren AJ, Ermens AAM, Gaál IO, Crișan TO, van de Veerdonk FL, Netea MG, Dinarello CA, Joosten LAB, Arts RJW; Radboudumc Center for Infectious Diseases COVID-19 Study Group. de Graaf DM, et al. Among authors: de nooijer ah. Immun Inflamm Dis. 2022 Nov;10(11):e712. doi: 10.1002/iid3.712. Immun Inflamm Dis. 2022. PMID: 36301025 Free PMC article.
28 results