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Lipoxins Protect Against Inflammation in Diabetes-Associated Atherosclerosis.
Brennan EP, Mohan M, McClelland A, de Gaetano M, Tikellis C, Marai M, Crean D, Dai A, Beuscart O, Derouiche S, Gray SP, Pickering R, Tan SM, Godson-Treacy M, Sheehan S, Dowdall JF, Barry M, Belton O, Ali-Shah ST, Guiry PJ, Jandeleit-Dahm K, Cooper ME, Godson C, Kantharidis P. Brennan EP, et al. Diabetes. 2018 Dec;67(12):2657-2667. doi: 10.2337/db17-1317. Epub 2018 Sep 13. Diabetes. 2018. PMID: 30213823
Asymmetric Synthesis and Biological Screening of Quinoxaline-Containing Synthetic Lipoxin A4 Mimetics (QNX-sLXms).
de Gaetano M, Tighe C, Gahan K, Zanetti A, Chen J, Newson J, Cacace A, Marai M, Gaffney A, Brennan E, Kantharidis P, Cooper ME, Leroy X, Perretti M, Gilroy D, Godson C, Guiry PJ. de Gaetano M, et al. J Med Chem. 2021 Jul 8;64(13):9193-9216. doi: 10.1021/acs.jmedchem.1c00403. Epub 2021 Jun 17. J Med Chem. 2021. PMID: 34138563 Free PMC article.
RAGE Deletion Confers Renoprotection by Reducing Responsiveness to Transforming Growth Factor-β and Increasing Resistance to Apoptosis.
Hagiwara S, Sourris K, Ziemann M, Tieqiao W, Mohan M, McClelland AD, Brennan E, Forbes J, Coughlan M, Harcourt B, Penfold S, Wang B, Higgins G, Pickering R, El-Osta A, Thomas MC, Cooper ME, Kantharidis P. Hagiwara S, et al. Diabetes. 2018 May;67(5):960-973. doi: 10.2337/db17-0538. Epub 2018 Feb 15. Diabetes. 2018. PMID: 29449307
Treatment with lipoxin A4 improves influenza A infection outcome, induces macrophage reprogramming, anti-inflammatory and pro-resolutive responses.
Rago F, Melo EM, Miller LM, Duray AM, Batista Felix F, Vago JP, de Faria Gonçalves AP, Angelo ALPM, Cassali GD, de Gaetano M, Brennan E, Owen B, Guiry P, Godson C, Alcorn JF, Teixeira MM. Rago F, et al. Inflamm Res. 2024 Nov;73(11):1903-1918. doi: 10.1007/s00011-024-01939-9. Epub 2024 Aug 30. Inflamm Res. 2024. PMID: 39214890
68 results