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Page 1
Plant-produced SARS-CoV-2 antibody engineered towards enhanced potency and in vivo efficacy.
de Taeye SW, Faye L, Morel B, Schriek AI, Umotoy JC, Yuan M, Kuzmina NA, Turner HL, Zhu X, Grünwald-Gruber C, Poniman M, Burger JA, Caniels TG, Fitchette AC, Desgagnés R, Stordeur V, Mirande L, Beauverger G, de Bree G, Ozorowski G, Ward AB, Wilson IA, Bukreyev A, Sanders RW, Vezina LP, Beaumont T, van Gils MJ, Gomord V. de Taeye SW, et al. Among authors: desgagnes r. Plant Biotechnol J. 2025 Jan;23(1):4-16. doi: 10.1111/pbi.14458. Epub 2024 Nov 19. Plant Biotechnol J. 2025. PMID: 39563066 Free PMC article.
Plant-produced Der p 2-bearing bioparticles activate Th1/Treg-related activation patterns in dendritic cells irrespective of the allergic background.
Busold S, Aglas L, Menage C, Desgagnés R, Faye L, Fitchette AC, de Jong EC, Martel C, Stigler M, Catala-Stordeur V, Tropper G, Auger L, Morel B, Versteeg SA, Vézina LP, Gomord V, Layhadi JA, Shamji M, Geijtenbeek TBH, van Ree R. Busold S, et al. Among authors: desgagnes r. Clin Exp Allergy. 2024 Apr;54(4):300-303. doi: 10.1111/cea.14456. Epub 2024 Jan 27. Clin Exp Allergy. 2024. PMID: 38279775 No abstract available.
A novel peanut allergy immunotherapy: Plant-based enveloped Ara h 2 Bioparticles activate dendritic cells and polarize T cell responses to Th1.
Castenmiller C, Nagy NA, Kroon PZ, Auger L, Desgagnés R, Martel C, Mirande L, Morel B, Roberge J, Stordeur V, Tropper G, Vézina LP, van Ree R, Gomord V, de Jong EC. Castenmiller C, et al. Among authors: desgagnes r. World Allergy Organ J. 2023 Nov 10;16(11):100839. doi: 10.1016/j.waojou.2023.100839. eCollection 2023 Nov. World Allergy Organ J. 2023. PMID: 38020282 Free PMC article.
Plant-based enveloped Ara h 2 bioparticles display exceptional hypo-allergenicity.
Castenmiller C, Stigler M, Kirpas ME, Versteeg S, Akkerdaas JH, Pena-Castellanos G, Blokhuis BR, Dreskin SC, Auger L, Desgagnés R, Martel C, Mirande L, Morel B, Roberge J, Stordeur V, Tropper G, Vézina LP, Gomord V, de Jong EC, Redegeld F, Shreffler WG, Aglas L, van Ree R. Castenmiller C, et al. Among authors: desgagnes r. Clin Exp Allergy. 2023 May;53(5):577-581. doi: 10.1111/cea.14294. Epub 2023 Feb 13. Clin Exp Allergy. 2023. PMID: 36779573 Free PMC article. No abstract available.
Fel d 1 surface expression on plant-made eBioparticles combines potent immune activation and hypoallergenicity.
Busold S, Aglas L, Menage C, Auger L, Desgagnés R, Faye L, Fitchette AC, de Jong EC, Martel C, Stigler M, Catala-Stordeur V, Tropper G, Vézina LP, Gomord V, Geijtenbeek TBH, van Ree R. Busold S, et al. Among authors: desgagnes r. Allergy. 2022 Oct;77(10):3124-3126. doi: 10.1111/all.15464. Epub 2022 Aug 8. Allergy. 2022. PMID: 35916123 Free PMC article. No abstract available.
Design, production and immunomodulatory potency of a novel allergen bioparticle.
Gomord V, Stordeur V, Fitchette AC, Fixman ED, Tropper G, Garnier L, Desgagnes R, Viel S, Couillard J, Beauverger G, Trepout S, Ward BJ, van Ree R, Faye L, Vézina LP. Gomord V, et al. Among authors: desgagnes r. PLoS One. 2020 Dec 1;15(12):e0242867. doi: 10.1371/journal.pone.0242867. eCollection 2020. PLoS One. 2020. PMID: 33259521 Free PMC article.