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Dominant negative variants in ITPR3 impair T cell Ca2+ dynamics causing combined immunodeficiency.
Blanco E, Camps C, Bahal S, Kerai MD, Ferla MP, Rochussen AM, Handel AE, Golwala ZM, Spiridou Goncalves H, Kricke S, Klein F, Zhang F, Zinghirino F, Evans G, Keane TM, Lizot S, Kusters MAA, Iro MA, Patel SV, Morris EC, Burns SO, Radcliffe R, Vasudevan P, Price A, Gillham O, Valdebenito GE, Stewart GS, Worth A, Adams SP, Duchen M, André I, Adams DJ, Santili G, Gilmour KC, Holländer GA, Davies EG, Taylor JC, Griffiths GM, Thrasher AJ, Dhalla F, Kreins AY. Blanco E, et al. Among authors: rochussen am. J Exp Med. 2025 Jan 6;222(1):e20220979. doi: 10.1084/jem.20220979. Epub 2024 Nov 19. J Exp Med. 2025. PMID: 39560673 Free PMC article.
NFIL3 contributes to cytotoxic T lymphocyte-mediated killing.
Douanne T, Strege K, Del Castillo Velasco-Herrera M, Rochussen AM, Adams DJ, Griffiths GM. Douanne T, et al. Among authors: rochussen am. Open Biol. 2024 Feb;14(2):230456. doi: 10.1098/rsob.230456. Epub 2024 Feb 28. Open Biol. 2024. PMID: 38412963 Free PMC article.
Imaging the T-cell receptor: new approaches, new insights.
Rochussen AM, Lippert AH, Griffiths GM. Rochussen AM, et al. Curr Opin Immunol. 2023 Jun;82:102309. doi: 10.1016/j.coi.2023.102309. Epub 2023 Apr 1. Curr Opin Immunol. 2023. PMID: 37011462 Free article. Review.