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The tyrosine kinase Yes1 is a druggable host factor of HEV.
Haase JA, Baheerathan A, Zhang X, Fu RM, Nocke MK, Decker C, Dao Thi VL, Todt D, Neyts J, Kaptein SJF, Steinmann E, Kinast V. Haase JA, et al. Among authors: kaptein sjf. Hepatol Commun. 2024 Oct 17;8(11):e0553. doi: 10.1097/HC9.0000000000000553. eCollection 2024 Nov 1. Hepatol Commun. 2024. PMID: 39560373 Free PMC article.
The rat cytomegalovirus homologue of parvoviral rep genes, r127, encodes a nuclear protein with single- and double-stranded DNA-binding activity that is dispensable for virus replication.
van Cleef KWR, Scaf WMA, Maes K, Kaptein SJF, Beuken E, Beisser PS, Stassen FRM, Grauls GELM, Bruggeman CA, Vink C. van Cleef KWR, et al. Among authors: kaptein sjf. J Gen Virol. 2004 Jul;85(Pt 7):2001-2013. doi: 10.1099/vir.0.79864-0. J Gen Virol. 2004. PMID: 15218186
Debio 025, a cyclophilin binding molecule, is highly efficient in clearing hepatitis C virus (HCV) replicon-containing cells when used alone or in combination with specifically targeted antiviral therapy for HCV (STAT-C) inhibitors.
Coelmont L, Kaptein S, Paeshuyse J, Vliegen I, Dumont JM, Vuagniaux G, Neyts J. Coelmont L, et al. Antimicrob Agents Chemother. 2009 Mar;53(3):967-76. doi: 10.1128/AAC.00939-08. Epub 2008 Dec 22. Antimicrob Agents Chemother. 2009. PMID: 19104013 Free PMC article.
A derivate of the antibiotic doxorubicin is a selective inhibitor of dengue and yellow fever virus replication in vitro.
Kaptein SJ, De Burghgraeve T, Froeyen M, Pastorino B, Alen MM, Mondotte JA, Herdewijn P, Jacobs M, de Lamballerie X, Schols D, Gamarnik AV, Sztaricskai F, Neyts J. Kaptein SJ, et al. Antimicrob Agents Chemother. 2010 Dec;54(12):5269-80. doi: 10.1128/AAC.00686-10. Epub 2010 Sep 13. Antimicrob Agents Chemother. 2010. PMID: 20837762 Free PMC article.
An analogue of the antibiotic teicoplanin prevents flavivirus entry in vitro.
De Burghgraeve T, Kaptein SJ, Ayala-Nunez NV, Mondotte JA, Pastorino B, Printsevskaya SS, de Lamballerie X, Jacobs M, Preobrazhenskaya M, Gamarnik AV, Smit JM, Neyts J. De Burghgraeve T, et al. PLoS One. 2012;7(5):e37244. doi: 10.1371/journal.pone.0037244. Epub 2012 May 18. PLoS One. 2012. PMID: 22624001 Free PMC article.
68 results