Toth K - Search Results

1

Synthesis of USC-093 and comparison with its promoiety enantiomer USC-093D against adenovirus in vitro and in a Syrian hamster model.

Yang J, Riemann SB, Lyu J, Feng S, Bi Y, Lentini NA, Kang I, Kashemirov BA, Hartline CB, James SH, Tollefson AE, Cline-Smith A, Toth K, McKenna CE. Yang J, et al. Among authors: toth k. bioRxiv [Preprint]. 2024 Nov 1:2024.11.01.621456. doi: 10.1101/2024.11.01.621456. bioRxiv. 2024. PMID: 39554161 Free PMC article. Preprint.

2

Oral USC-093, a novel homoserinamide analogue of the tyrosinamide (S)-HPMPA prodrug USC-087 has decreased nephrotoxicity while maintaining antiviral efficacy against human adenovirus infection of Syrian hamsters.

Tollefson AE, Riemann SB, Ying B, Spencer JF, Overhulse JM, Kashemirov BA, Wold WSM, McKenna CE, Toth K. Tollefson AE, et al. Among authors: toth k. Antiviral Res. 2024 Feb;222:105799. doi: 10.1016/j.antiviral.2024.105799. Epub 2024 Jan 6. Antiviral Res. 2024. PMID: 38190973

3

USC-087 protects Syrian hamsters against lethal challenge with human species C adenoviruses.

Toth K, Spencer JF, Ying B, Tollefson AE, Hartline CB, Richard ET, Fan J, Lyu J, Kashemirov BA, Harteg C, Reyna D, Lipka E, Prichard MN, McKenna CE, Wold WSM. Toth K, et al. Antiviral Res. 2018 May;153:1-9. doi: 10.1016/j.antiviral.2018.03.001. Epub 2018 Mar 3. Antiviral Res. 2018. PMID: 29510156 Free PMC article.

4

NPP-669, a prodrug of cidofovir, is highly efficacious against human adenovirus infection in the permissive Syrian hamster model.

Tollefson AE, Cline-Smith AB, Spencer JF, Reyna DM, Lipka E, Toth K. Tollefson AE, et al. Among authors: toth k. Antimicrob Agents Chemother. 2024 Jul 9;68(7):e0048924. doi: 10.1128/aac.00489-24. Epub 2024 May 22. Antimicrob Agents Chemother. 2024. PMID: 38775484 Free PMC article.

5

Combination therapy with brincidofovir and valganciclovir against species C adenovirus infection in the immunosuppressed Syrian hamster model allows for substantial reduction of dose for both compounds.

Toth K, Tollefson AE, Spencer JF, Ying B, Wold WSM. Toth K, et al. Antiviral Res. 2017 Oct;146:121-129. doi: 10.1016/j.antiviral.2017.08.002. Epub 2017 Aug 4. Antiviral Res. 2017. PMID: 28827083

6

Longitudinal Monitoring of the Effects of Anti-Adenoviral Treatment Regimens in a Permissive In Vivo Model.

Tollefson AE, Cline-Smith A, Spencer JF, Ying B, Reyna DM, Lipka E, James SH, Toth K. Tollefson AE, et al. Among authors: toth k. Viruses. 2024 Jul 26;16(8):1200. doi: 10.3390/v16081200. Viruses. 2024. PMID: 39205174 Free PMC article.

7

HAdV-C6 Is a More Relevant Challenge Virus than HAdV-C5 for Testing Antiviral Drugs with the Immunosuppressed Syrian Hamster Model.

Toth K, Spencer JF, Ying B, Tollefson AE, Wold WSM. Toth K, et al. Viruses. 2017 Jun 13;9(6):147. doi: 10.3390/v9060147. Viruses. 2017. PMID: 28608847 Free PMC article.

8

Drug development against human adenoviruses and its advancement by Syrian hamster models.

Wold WSM, Tollefson AE, Ying B, Spencer JF, Toth K. Wold WSM, et al. Among authors: toth k. FEMS Microbiol Rev. 2019 Jul 1;43(4):380-388. doi: 10.1093/femsre/fuz008. FEMS Microbiol Rev. 2019. PMID: 30916746 Review.

9

Filociclovir is a potent inhibitor of human adenovirus F41.

Tollefson AE, Hussein ITM, Toth K, Bowlin TL. Tollefson AE, et al. Among authors: toth k. Antiviral Res. 2022 Dec;208:105431. doi: 10.1016/j.antiviral.2022.105431. Epub 2022 Oct 7. Antiviral Res. 2022. PMID: 36209985

10

Cidofovir and brincidofovir reduce the pathology caused by systemic infection with human type 5 adenovirus in immunosuppressed Syrian hamsters, while ribavirin is largely ineffective in this model.

Tollefson AE, Spencer JF, Ying B, Buller RM, Wold WS, Toth K. Tollefson AE, et al. Among authors: toth k. Antiviral Res. 2014 Dec;112:38-46. doi: 10.1016/j.antiviral.2014.10.005. Epub 2014 Oct 15. Antiviral Res. 2014. PMID: 25453340

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

1,183 results

Search Page

Filters