McKenna CE - Search Results

1

Synthesis of USC-093 and comparison with its promoiety enantiomer USC-093D against adenovirus in vitro and in a Syrian hamster model.

Yang J, Riemann SB, Lyu J, Feng S, Bi Y, Lentini NA, Kang I, Kashemirov BA, Hartline CB, James SH, Tollefson AE, Cline-Smith A, Toth K, McKenna CE. Yang J, et al. Among authors: mckenna ce. bioRxiv [Preprint]. 2024 Nov 1:2024.11.01.621456. doi: 10.1101/2024.11.01.621456. bioRxiv. 2024. PMID: 39554161 Free PMC article. Preprint.

2

USC-087 protects Syrian hamsters against lethal challenge with human species C adenoviruses.

Toth K, Spencer JF, Ying B, Tollefson AE, Hartline CB, Richard ET, Fan J, Lyu J, Kashemirov BA, Harteg C, Reyna D, Lipka E, Prichard MN, McKenna CE, Wold WSM. Toth K, et al. Among authors: mckenna ce. Antiviral Res. 2018 May;153:1-9. doi: 10.1016/j.antiviral.2018.03.001. Epub 2018 Mar 3. Antiviral Res. 2018. PMID: 29510156 Free PMC article.

3

Uridine Bisphosphonates Differentiate Phosphoglycosyl Transferase Superfamilies.

Seebald LM, Haratipour P, Jacobs MR, Bernstein HM, Kashemirov BA, McKenna CE, Imperiali B. Seebald LM, et al. Among authors: mckenna ce. bioRxiv [Preprint]. 2023 Sep 19:2023.09.19.558431. doi: 10.1101/2023.09.19.558431. bioRxiv. 2023. Update in: J Am Chem Soc. 2024 Feb 7;146(5):3220-3229. doi: 10.1021/jacs.3c11402 PMID: 37786673 Free PMC article. Updated. Preprint.

4

Evolution of an amino acid based prodrug approach: stay tuned.

Krylov IS, Kashemirov BA, Hilfinger JM, McKenna CE. Krylov IS, et al. Among authors: mckenna ce. Mol Pharm. 2013 Feb 4;10(2):445-58. doi: 10.1021/mp300663j. Epub 2013 Jan 22. Mol Pharm. 2013. PMID: 23339402 Free PMC article.

5

Approaches to tyrosine-linked peptidomimetic prodrugs of (S)-HPMP-based acyclic nucleoside phosphonates.

Zakharova VM, Krylov IS, Serpi M, Kashemirov BA, McKenna CE. Zakharova VM, et al. Among authors: mckenna ce. Phosphorus Sulfur Silicon Relat Elem. 2011;186(4):968-969. doi: 10.1080/10426507.2010.526676. Phosphorus Sulfur Silicon Relat Elem. 2011. PMID: 21566698 Free PMC article.

6

On the observation of discrete fluorine NMR spectra for uridine 5'-β,γ-fluoromethylenetriphosphate diastereomers at basic pH.

Hwang CS, Kashemirov BA, McKenna CE. Hwang CS, et al. Among authors: mckenna ce. J Org Chem. 2014 Jun 6;79(11):5315-9. doi: 10.1021/jo500452b. Epub 2014 May 12. J Org Chem. 2014. PMID: 24819695 Free PMC article.

7

An acyclic phosphonate prodrug of HPMPC is effective against VZV in skin organ culture and mice.

Lloyd MG, Liu D, Lyu J, Fan J, Overhulse JM, Kashemirov BA, Prichard MN, McKenna CE, Moffat JF. Lloyd MG, et al. Among authors: mckenna ce. Antiviral Res. 2022 Mar;199:105275. doi: 10.1016/j.antiviral.2022.105275. Epub 2022 Mar 3. Antiviral Res. 2022. PMID: 35248614 Free article.

8

Carbonylbisphosphonate and (diazomethylene)bisphosphonate analogues of AZT 5(')-diphosphate.

McKenna CE, Kashemirov BA, Rozé CN. McKenna CE, et al. Bioorg Chem. 2002 Dec;30(6):383-95. doi: 10.1016/s0045-2068(02)00521-7. Bioorg Chem. 2002. PMID: 12642124

9

Synthesis and stability studies of phosphonoformate-amino acid conjugates: a new class of slowly releasing foscarnet prodrugs.

Marma MS, Kashemirov BA, McKenna CE. Marma MS, et al. Among authors: mckenna ce. Bioorg Med Chem Lett. 2004 Apr 5;14(7):1787-90. doi: 10.1016/j.bmcl.2004.01.016. Bioorg Med Chem Lett. 2004. PMID: 15026072

10

Serine side chain-linked peptidomimetic conjugates of cyclic HPMPC and HPMPA: synthesis and interaction with hPEPT1.

Peterson LW, Sala-Rabanal M, Krylov IS, Serpi M, Kashemirov BA, McKenna CE. Peterson LW, et al. Among authors: mckenna ce. Mol Pharm. 2010 Dec 6;7(6):2349-61. doi: 10.1021/mp100186b. Epub 2010 Oct 7. Mol Pharm. 2010. PMID: 20929265 Free PMC article.

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