Bracher F - Search Results

1

Sirtuin2 blockade inhibits replication of Human Immunodeficiency Virus-1 and Mycobacterium tuberculosis in macrophages and humanized mice.

Singh VK, Mishra A, Truong K, Bohorquez JA, Sharma S, Khan A, Bracher F, Zhang K, Endsley J, Endsley M, Rice AP, Kimata JT, Yi G, Jagannath C. Singh VK, et al. Among authors: bracher f. bioRxiv [Preprint]. 2024 Oct 29:2024.10.27.620499. doi: 10.1101/2024.10.27.620499. bioRxiv. 2024. PMID: 39553987 Free PMC article. Preprint.

2

Aromatic Amino Acid Hydroxylases as Off-Targets of Histone Deacetylase Inhibitors.

Baumann A, Papenkordt N, Robaa D, Szigetvari PD, Vogelmann A, Bracher F, Sippl W, Jung M, Haavik J. Baumann A, et al. Among authors: bracher f. ACS Chem Neurosci. 2024 Nov 20;15(22):4143-4155. doi: 10.1021/acschemneuro.4c00346. Epub 2024 Nov 10. ACS Chem Neurosci. 2024. PMID: 39523540 Free PMC article.

3

Structural basis for inhibition of the lysosomal two-pore channel TPC2 by a small molecule antagonist.

Chi G, Jaślan D, Kudrina V, Böck J, Li H, Pike ACW, Rautenberg S, Krogsaeter E, Bohstedt T, Wang D, McKinley G, Fernandez-Cid A, Mukhopadhyay SMM, Burgess-Brown NA, Keller M, Bracher F, Grimm C, Dürr KL. Chi G, et al. Among authors: bracher f. Structure. 2024 Aug 8;32(8):1137-1149.e4. doi: 10.1016/j.str.2024.05.005. Epub 2024 May 29. Structure. 2024. PMID: 38815576 Free PMC article.

4

Synthesis of a Side Chain Alkyne Analogue of Sitosterol as a Chemical Probe for Imaging in Plant Cells.

Hollweck M, Jordan D, Bracher F. Hollweck M, et al. Among authors: bracher f. Biomolecules. 2024 Apr 30;14(5):542. doi: 10.3390/biom14050542. Biomolecules. 2024. PMID: 38785949 Free PMC article.

5

DHCR24 inhibitor SH42 increases desmosterol without preventing atherosclerosis development in mice.

Ge X, Slütter B, Lambooij JM, Zhou E, Ying Z, Agirman C, Heijink M, Rimbert A, Guigas B, Kuiper J, Müller C, Bracher F, Giera M, Kooijman S, Rensen PCN, Wang Y, Schönke M. Ge X, et al. Among authors: bracher f. iScience. 2024 Apr 26;27(6):109830. doi: 10.1016/j.isci.2024.109830. eCollection 2024 Jun 21. iScience. 2024. PMID: 38770137 Free PMC article.

6

Coordinating activation of endo-lysosomal two-pore channels and TRP mucolipins.

Yuan Y, Jaślan D, Rahman T, Bracher F, Grimm C, Patel S. Yuan Y, et al. Among authors: bracher f. J Physiol. 2024 Apr;602(8):1623-1636. doi: 10.1113/JP283829. Epub 2024 Apr 10. J Physiol. 2024. PMID: 38598430

7

Potent hydroxamate-derived compounds arrest endodyogeny of Toxoplasma gondii tachyzoites.

Araujo-Silva CA, Vögerl K, Breu F, Jung M, Costa ALO, De Souza W, Bracher F, Martins-Duarte ES, Vommaro RC. Araujo-Silva CA, et al. Among authors: bracher f. Exp Parasitol. 2024 Apr;259:108727. doi: 10.1016/j.exppara.2024.108727. Epub 2024 Mar 1. Exp Parasitol. 2024. PMID: 38431113

8

2-Desaza-annomontine (C81) impedes angiogenesis through reduced VEGFR2 expression derived from inhibition of CDC2-like kinases.

Zech TJ, Wolf A, Hector M, Bischoff-Kont I, Krishnathas GM, Kuntschar S, Schmid T, Bracher F, Langmann T, Fürst R. Zech TJ, et al. Among authors: bracher f. Angiogenesis. 2024 May;27(2):245-272. doi: 10.1007/s10456-024-09906-y. Epub 2024 Feb 26. Angiogenesis. 2024. PMID: 38403816 Free PMC article.

9

Correction: Synthesis of highly substituted fluorenones via metal-free TBHP-promoted oxidative cyclization of 2-(aminomethyl)biphenyls. Application to the total synthesis of nobilone.

Jourjine IAP, Zeisel L, Krauß J, Bracher F. Jourjine IAP, et al. Among authors: bracher f. Beilstein J Org Chem. 2024 Jan 30;20:170-172. doi: 10.3762/bjoc.20.16. eCollection 2024. Beilstein J Org Chem. 2024. PMID: 38318461 Free PMC article.

10

Two-pore channel-2 and inositol trisphosphate receptors coordinate Ca²⁺ signals between lysosomes and the endoplasmic reticulum.

Yuan Y, Arige V, Saito R, Mu Q, Brailoiu GC, Pereira GJS, Bolsover SR, Keller M, Bracher F, Grimm C, Brailoiu E, Marchant JS, Yule DI, Patel S. Yuan Y, et al. Among authors: bracher f. Cell Rep. 2024 Jan 23;43(1):113628. doi: 10.1016/j.celrep.2023.113628. Epub 2023 Dec 30. Cell Rep. 2024. PMID: 38160394 Free PMC article.

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