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The glycosyltransferase ST3GAL4 drives immune evasion in acute myeloid leukemia by synthesizing ligands for the glyco-immune checkpoint receptor Siglec-9.
Krishnamoorthy V, Daly J, Kim J, Piatnitca L, Yuen KA, Kumar B, Taherzadeh Ghahfarrokhi M, Bui TQT, Azadi P, Vu LP, Wisnovsky S. Krishnamoorthy V, et al. Among authors: taherzadeh ghahfarrokhi m. Leukemia. 2024 Nov 17. doi: 10.1038/s41375-024-02454-w. Online ahead of print. Leukemia. 2024. PMID: 39551873
Fucosylation of glycoproteins and glycolipids: opposing roles in cholera intoxication.
Ghorashi AC, Boucher A, Archer-Hartmann SA, Zalem D, Taherzadeh Ghahfarrokhi M, Murray NB, Konada RSR, Zhang X, Xing C, Teneberg S, Azadi P, Yrlid U, Kohler JJ. Ghorashi AC, et al. Among authors: taherzadeh ghahfarrokhi m. Nat Chem Biol. 2024 Oct 16. doi: 10.1038/s41589-024-01748-5. Online ahead of print. Nat Chem Biol. 2024. PMID: 39414978