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Page 1
Inhibition of Cbl-b restores effector functions of human intratumoral NK cells.
Tundo S, Trefny M, Rodić A, Grueninger O, Brodmann N, Börsch A, Serger C, Fürst J, Buchi M, Buczak K, Müller AT, Sach-Peltason L, Don L, Herzig P, Lardinois D, Heinzelmann-Schwarz V, Mertz KD, Hojski A, Schaeuble K, Laubli H, Natoli M, Toso A, Luu TT, Zippelius A, Romagnani A. Tundo S, et al. Among authors: trefny m. J Immunother Cancer. 2024 Nov 17;12(11):e009860. doi: 10.1136/jitc-2024-009860. J Immunother Cancer. 2024. PMID: 39551607 Free PMC article.
13C tracer analysis reveals the landscape of metabolic checkpoints in human CD8+ T cell differentiation and exhaustion.
Kirchmair A, Nemati N, Lamberti G, Trefny M, Krogsdam A, Siller A, Hörtnagl P, Schumacher P, Sopper S, Sandbichler A, Zippelius A, Ghesquière B, Trajanoski Z. Kirchmair A, et al. Among authors: trefny m. Front Immunol. 2023 Oct 19;14:1267816. doi: 10.3389/fimmu.2023.1267816. eCollection 2023. Front Immunol. 2023. PMID: 37928527 Free PMC article.
Tumor-derived prostaglandin E2 programs cDC1 dysfunction to impair intratumoral orchestration of anti-cancer T cell responses.
Bayerl F, Meiser P, Donakonda S, Hirschberger A, Lacher SB, Pedde AM, Hermann CD, Elewaut A, Knolle M, Ramsauer L, Rudolph TJ, Grassmann S, Öllinger R, Kirchhammer N, Trefny M, Anton M, Wohlleber D, Höchst B, Zaremba A, Krüger A, Rad R, Obenauf AC, Schadendorf D, Zippelius A, Buchholz VR, Schraml BU, Böttcher JP. Bayerl F, et al. Among authors: trefny m. Immunity. 2023 Jun 13;56(6):1341-1358.e11. doi: 10.1016/j.immuni.2023.05.011. Immunity. 2023. PMID: 37315536 Free article.
Dual TLR9 and PD-L1 targeting unleashes dendritic cells to induce durable antitumor immunity.
Fernandez-Rodriguez L, Cianciaruso C, Bill R, Trefny MP, Klar R, Kirchhammer N, Buchi M, Festag J, Michel S, Kohler RH, Jones E, Maaske A, Vom Berg J, Kobold S, Kashyap AS, Jaschinski F, Dixon KO, Pittet MJ, Zippelius A. Fernandez-Rodriguez L, et al. Among authors: trefny mp. J Immunother Cancer. 2023 May;11(5):e006714. doi: 10.1136/jitc-2023-006714. J Immunother Cancer. 2023. PMID: 37208130 Free PMC article.
N-acetylcysteine overcomes NF1 loss-driven resistance to PI3Kα inhibition in breast cancer.
Auf der Maur P, Trefny MP, Baumann Z, Vulin M, Correia AL, Diepenbruck M, Kramer N, Volkmann K, Preca BT, Ramos P, Leroy C, Eichlisberger T, Buczak K, Zilli F, Okamoto R, Rad R, Jensen MR, Fritsch C, Zippelius A, Stadler MB, Bentires-Alj M. Auf der Maur P, et al. Among authors: trefny mp. Cell Rep Med. 2023 Apr 18;4(4):101002. doi: 10.1016/j.xcrm.2023.101002. Epub 2023 Apr 11. Cell Rep Med. 2023. PMID: 37044095 Free PMC article.
Deletion of SNX9 alleviates CD8 T cell exhaustion for effective cellular cancer immunotherapy.
Trefny MP, Kirchhammer N, Auf der Maur P, Natoli M, Schmid D, Germann M, Fernandez Rodriguez L, Herzig P, Lötscher J, Akrami M, Stinchcombe JC, Stanczak MA, Zingg A, Buchi M, Roux J, Marone R, Don L, Lardinois D, Wiese M, Jeker LT, Bentires-Alj M, Rossy J, Thommen DS, Griffiths GM, Läubli H, Hess C, Zippelius A. Trefny MP, et al. Nat Commun. 2023 Feb 2;14(1):86. doi: 10.1038/s41467-022-35583-w. Nat Commun. 2023. PMID: 36732507 Free PMC article.
Analysis of Antibiotic Exposure and Early-Onset Neonatal Sepsis in Europe, North America, and Australia.
Giannoni E, Dimopoulou V, Klingenberg C, Navér L, Nordberg V, Berardi A, El Helou S, Fusch G, Bliss JM, Lehnick D, Guerina N, Seliga-Siwecka J, Maton P, Lagae D, Mari J, Janota J, Agyeman PKA, Pfister R, Latorre G, Maffei G, Laforgia N, Mózes E, Størdal K, Strunk T, Stocker M; AENEAS Study Group. Giannoni E, et al. JAMA Netw Open. 2022 Nov 1;5(11):e2243691. doi: 10.1001/jamanetworkopen.2022.43691. JAMA Netw Open. 2022. PMID: 36416819 Free PMC article.
33 results